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How to get fromKarlsruhe to Pragueby train, bus, night train, car, or plane

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There are 11 ways to get from Karlsruhe to Prague by train, bus, night train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus via Nuremberg

    best
    1. Take the train from Karlsruhe Hauptbahnhof to Nürnberg Hbftrain train 61
    2. Take the bus from Nuremberg central bus station to Praguebus bus N109 / ...
    7h 36m
    Kč 1,722–3,255

  2. Bus

    cheapest
    1. Take the bus from Karlsruhe central train station to Praha, ÚAN Florencbus bus N1315 / ...
    9h
    Kč 1,200–1,800

  3. Train

    1. Take the train from Karlsruhe Hauptbahnhof to Nürnberg Hbftrain train 61
    2. Take the train from Nürnberg Hbf to Schwandorftrain train
    3. Take the train from Schwandorf to Praha Hlavni Nadrazitrain train Re
    9h 26m
    Kč 2,572–4,865

  4. Night train

    1. Take the nighttrain from Karlsruhe Hbf to Praha Hlavni Nadrazinighttrain night train En
    10h 16m
    Kč 3,500–6,000

  5. Drive  522.2 km

    1. Drive from Karlsruhe to Praguecar car 522.2 km
    4h 29m
    Kč 2,376–3,432

  6. Train, bus

    1. Take the train from Wilferdingen-Singen Bahnhof to Hauptbahnhoftrain train Re1
    2. Take the bus from Stuttgart to Praha Hlavní nádražíbus bus Ivano-Frankivsk
    12h 36m
    Kč 1,975–2,646

  7. Train to Frankfurt, fly to Václav Havel Airport Prague

    1. Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Václav Havel Airport Prague (PRG)plane plane FRA - PRG
    4h 40m
    Kč 1,883–3,957

  8. Train to Stuttgart Airport, fly to Václav Havel Airport Prague

    1. Take the train from Karlsruhe Hbf to Stuttgart Hbftrain train
    2. Fly from Stuttgart Airport (STR) to Václav Havel Airport Prague (PRG)plane plane STR - PRG
    6h 20m
    Kč 2,822–7,792

  9. Train to Frankfurt, fly to Dresden Airport, bus

    1. Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Dresden Airport (DRS)plane plane FRA - DRS
    3. Take the bus from Dresden central station to Praha, ÚAN Florencbus bus
    5h 45m
    Kč 3,765–8,597

  10. Train, train to Munich International Airport, fly to Václav Havel Airport Prague

    1. Take the train from Karlsruhe Hauptbahnhof to Pasingtrain train
    2. Take the train from Pasing to Flughafen Münchentrain train
    3. Fly from Munich International Airport (MUC) to Václav Havel Airport Prague (PRG)plane plane MUC - PRG
    5h 58m
    Kč 3,911–8,283

  11. Train, train to Zurich Airport, fly to Václav Havel Airport Prague

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train
    2. Take the train from Basel SBB to Zürich HBtrain train
    3. Fly from Zurich Airport (ZRH) to Václav Havel Airport Prague (PRG)plane plane ZRH - PRG
    7h 18m
    Kč 3,270–8,697

Karlsruhe to Prague by train and bus

Calendar64Weekly Services
Duration7h 36mAverage Duration
TicketKč 1,722Cheapest Price
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Comparing Your Travel Options

Map of how to get from Karlsruhe to Prague.ExpandLaunch map view
  • Distance: 569.2 km
  • Duration: 7h 36m

What companies run services between Karlsruhe, Germany and Prague, Czechia?

You can take a train from Karlsruhe Hauptbahnhof to Praha Hlavni Nadrazi via Nürnberg Hbf, Nürnberg Hbf, and Schwandorf in around 9h 26m. Alternatively, FlixBus operates a bus from Karlsruhe central train station to Praha, ÚAN Florenc every 4 hours. Tickets cost Kč 1,200–1,800 and the journey takes 9h.

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