There are 10 ways to get from Karlsruhe to Santander by train, plane, bus, car, or train (TGV, Renfe)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Stuttgart Airport, fly to Santander Airport
best- Take the train from Karlsruhe Hbf to Stuttgart Hbftrain
- Fly from Stuttgart Airport (STR) to Santander Airport (SDR)plane STR - SDR
8h 21m€101–432Train to Stuttgart Airport, fly to Bilbao Airport, bus
cheapest- Take the train from Karlsruhe Hbf to Stuttgart Hbftrain
- Fly from Stuttgart Airport (STR) to Bilbao Airport (BIO)plane STR - BIO
- Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus
8h 24m€95–298Train, bus
- Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain 83 / ...
- Take the train from Strasbourg to Bordeaux St Jeantrain Tgv
- Take the bus from Bordeaux to Estación de autobuses de Santanderbus
14h 56m€250–400Bus
- Take the bus from Karlsruhe - Central Station South Side to Paris - Bercy-Seine Bus Stationbus BlaBlaCar Bus
- Take the bus from Paris to Estación de autobuses de Santanderbus FlixBus 783
21h 40m€126–197Drive 1,415.4 km
- Drive from Karlsruhe to Santandercar 1,415.4 km
13h 53m€231–334Train to Frankfurt, fly to Bilbao Airport, bus
- Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Bilbao Airport (BIO)plane FRA - BIO
- Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus
8h 12m€118–294Train, train to Zurich Airport, fly to Bilbao Airport, bus
- Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain
- Take the train from Basel SBB to Zürich HBtrain
- Fly from Zurich Airport (ZRH) to Bilbao Airport (BIO)plane ZRH - BIO
- Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus
10h 14m€137–371Train, bus via Antony
- Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain 83 / ...
- Take the train from Strasbourg to Massy Tgvtrain Tgv
- Take the train from Massy Tgv to St Jean De Luz Cibouretrain Tgv
- Take the bus from Saint-Jean-de-Luz to Bilbao Intermodalbus
- Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus
15h 18m€257–429Train
- Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain 83 / ...
- Take the train from Strasbourg to Bordeaux St Jeantrain Tgv
- Take the train from Bordeaux St Jean to Hendayetrain Ter
- Take the train from Amara-Donostia to Zazpikaleak/Casco Viejo-Bilbaotrain E1
- Take the train from Bilbao to Santandertrain
19h 20m€270–446Train, bus via Paris Orly Airport (ORY)
- Take the train from Karlsruhe Hauptbahnhof to Neustadt, Hauptbahnhoftrain Re6
- Take the train from Neustadt, Hauptbahnhof to Saarbrücken Hbftrain Re1
- Take the train from Saarbrücken Hbf to Paris Gare de Lyontrain 82
- Take the bus from Aéroport Orly 4 to Bilbao Intermodalbus
- Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus
22h 45m€149–338
Karlsruhe to Santander by train, foot, and bus
Comparing Your Travel Options
The cheapest way to get from Karlsruhe to Santander is to bus which costs €120 - €200 and takes 21h 40m.
The fastest way to get from Karlsruhe to Santander is to train and fly and bus which takes 8h 12m and costs €110 - €300.
No, there is no direct bus from Karlsruhe station to Santander. However, there are services departing from Karlsruhe - Central Station South Side and arriving at Estación de autobuses de Santander via Paris. The journey, including transfers, takes approximately 21h 40m.
No, there is no direct train from Karlsruhe to Santander. However, there are services departing from Karlsruhe Hauptbahnhof and arriving at Santander via Strasbourg, Bordeaux St Jean, Hendaia, Amara-Donostia and Bilbao. The journey, including transfers, takes approximately 19h 20m.
The distance between Karlsruhe and Santander is 1260 km. The road distance is 1415.4 km.
The best way to get from Karlsruhe to Santander without a car is to train and bus which takes 14h 56m and costs €250 - €400.
It takes approximately 8h 21m to get from Karlsruhe to Santander, including transfers.
Karlsruhe to Santander bus services, operated by BlaBlaCar Bus, depart from Karlsruhe - Central Station South Side.
Karlsruhe to Santander train services, operated by Deutsche Bahn Intercity (DB IC), depart from Karlsruhe Hauptbahnhof station.
The best way to get from Karlsruhe to Santander is to bus which takes 21h 40m and costs €120 - €200. Alternatively, you can train, which costs €270 - €450 and takes 19h 20m.
What companies run services between Karlsruhe, Germany and Santander, Spain?
You can take a bus from Karlsruhe - Central Station South Side to Estación de autobuses de Santander via Paris - Bercy-Seine Bus Station and Paris in around 21h 40m. Alternatively, you can take a train from Karlsruhe Hauptbahnhof to Santander via Strasbourg Bahnhof, Strasbourg, Bordeaux St Jean, Hendaye, Hendaia, Amara-Donostia, Zazpikaleak/Casco Viejo-Bilbao, and Bilbao in around 19h 20m.
- Website
- vueling.com
Flights from Stuttgart Airport to Santander Airport via Barcelona
- Ave. Duration
- 4h 52m
- When
- Tuesday, Thursday, Friday, and Saturday
- Estimated price
- €85–430
Flights from Stuttgart Airport to Santander Airport via Alicante–Elche
- Ave. Duration
- 5h
- When
- Thursday and Saturday
- Estimated price
- €110–450
Flights from Stuttgart Airport to Santander Airport via Palma Mallorca
- Ave. Duration
- 6h 15m
- When
- Friday
- Estimated price
- €110–440
Flights from Stuttgart Airport to Bilbao Airport via Barcelona
- Ave. Duration
- 4h 36m
- When
- Friday, Wednesday, Thursday, and Sunday
- Estimated price
- €80–200
Flights from Zurich Airport to Bilbao Airport via Barcelona
- Ave. Duration
- 4h 27m
- When
- Sunday and Friday
- Estimated price
- €70–210
- Website
- lufthansa.com
Flights from Stuttgart Airport to Bilbao Airport via Munich
- Ave. Duration
- 4h 45m
- When
- Every day
- Estimated price
- €100–370
Flights from Frankfurt to Bilbao Airport
- Ave. Duration
- 2h 10m
- When
- Every day
- Estimated price
- €55–320
Flights from Zurich Airport to Bilbao Airport via Frankfurt
- Ave. Duration
- 4h 27m
- When
- Monday, Wednesday, Thursday, and Sunday
- Estimated price
- €90–320
- Website
- swiss.com
Flights from Frankfurt to Bilbao Airport
- Ave. Duration
- 2h 10m
- When
- Every day
- Estimated price
- €90–320
Flights from Frankfurt to Bilbao Airport via Zurich Airport
- Ave. Duration
- 4h 32m
- When
- Tuesday, Thursday, Friday, and Sunday
- Estimated price
- €60–320
Flights from Zurich Airport to Bilbao Airport
- Ave. Duration
- 1h 55m
- When
- Tuesday, Thursday, Friday, and Sunday
- Estimated price
- €50–280
Flights from Zurich Airport to Bilbao Airport via Frankfurt
- Ave. Duration
- 4h 40m
- When
- Monday
- Estimated price
- €90–320
- Website
- brusselsairlines.com
Flights from Frankfurt to Bilbao Airport via Brussels
- Ave. Duration
- 4h 55m
- When
- Wednesday, Sunday, Monday, Tuesday, Thursday, and Friday
- Estimated price
- €65–250
- Website
- volotea.com
Flights from Stuttgart Airport to Santander Airport via Malaga
- Ave. Duration
- 5h 20m
- When
- Tuesday
- Estimated price
- €110–460
- Website
- flyulendo.com
Flights from Stuttgart Airport to Santander Airport via Valencia
- Ave. Duration
- 6h 50m
- When
- Tuesday and Saturday
- Estimated price
- €110–440
- Website
- eurowings.com
Flights from Stuttgart Airport to Bilbao Airport
- Ave. Duration
- 2h
- When
- Wednesday to Friday
- Estimated price
- €60–210
- Website
- lufthansa-city.com
Flights from Frankfurt to Bilbao Airport
- Ave. Duration
- 2h 10m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €55–300
- Website
- luxair.lu
Flights from Frankfurt to Bilbao Airport via Luxembourg
- Ave. Duration
- 5h 5m
- When
- Thursday and Sunday
- Estimated price
- €90–370
- Website
- flyedelweiss.com
Flights from Zurich Airport to Bilbao Airport
- Ave. Duration
- 1h 55m
- When
- Tuesday, Thursday, Friday, and Sunday
- Estimated price
- €50–280
- Phone
- +49 711 400 534 44
- [email protected]
- Website
- Arverio Baden-Württemberg
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €14–27
- Schedules at
- Arverio Baden-Württemberg
- 2nd Class Ticket
- €14–18
- 1st Class Ticket
- €18–27
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €14–27
- Schedules at
- Arverio Baden-Württemberg
- 2nd Class Ticket
- €14–18
- 1st Class Ticket
- €18–27
- Phone
- +49 711 400 534 44
- [email protected]
- Website
- Arverio Baden-Württemberg GmbH
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €14–20
- Schedules at
- Arverio Baden-Württemberg GmbH
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €14–20
- Schedules at
- Arverio Baden-Württemberg GmbH
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 47 min
- Frequency
- Every 3 hours
- Estimated price
- €14–30
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhof
- Ave. Duration
- 43 min
- Frequency
- Every 4 hours
- Estimated price
- €15–30
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 47 min
- Frequency
- Every 3 hours
- Estimated price
- €14–30
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Frankfurt
- Ave. Duration
- 1h 9m
- Frequency
- Every 4 hours
- Estimated price
- €23–50
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Basel SBB
- Ave. Duration
- 1h 48m
- Frequency
- Hourly
- Estimated price
- €35–75
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhof
- Ave. Duration
- 43 min
- Frequency
- Every 4 hours
- Estimated price
- €15–30
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhof
- Ave. Duration
- 43 min
- Frequency
- Every 4 hours
- Estimated price
- €15–30
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Neustadt, Hauptbahnhof to Saarbrücken Hbf
- Ave. Duration
- 1h 5m
- Frequency
- 4 times a day
- Estimated price
- €18–40
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 37 min
- Frequency
- 3 times a day
- Estimated price
- €16–24
- Website
- TGV inOui
Train from Strasbourg to Bordeaux St Jean
- Ave. Duration
- 6h 1m
- Frequency
- Twice daily
- Estimated price
- €200–310
- Website
- TGV inOui
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 37 min
- Frequency
- 3 times a day
- Estimated price
- €16–24
- Website
- TGV inOui
Train from Strasbourg to Massy Tgv
- Ave. Duration
- 3h 3m
- Frequency
- Every 3 hours
- Estimated price
- €95–150
- Website
- TGV inOui
Train from Massy Tgv to St Jean De Luz Ciboure
- Ave. Duration
- 4h 24m
- Frequency
- 6 times a week
- Estimated price
- €140–220
- Website
- TGV inOui
Train from Strasbourg to Bordeaux St Jean
- Ave. Duration
- 6h 1m
- Frequency
- Twice daily
- Estimated price
- €200–310
- Website
- TGV inOui
Train from Bordeaux St Jean to Hendaye
- Ave. Duration
- 2h 27m
- Frequency
- Every 3 hours
- Estimated price
- €45–70
- Website
- TGV inOui
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 1h 36m
- Frequency
- 5 times a week
- Estimated price
- €12–55
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 1h 36m
- Frequency
- 5 times a week
- Estimated price
- €12–55
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Karlsruhe Hauptbahnhof to Neustadt, Hauptbahnhof
- Ave. Duration
- 1h 9m
- Frequency
- Hourly
- Estimated price
- €9–40
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Karlsruhe Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 18m
- Frequency
- Twice daily
- Estimated price
- €21–45
- Website
- Nederlandse Spoorwegen (NS)
- Phone
- +43 5 1717
- Website
- Österreichische Bundesbahnen
Train from Karlsruhe Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 17m
- Frequency
- Twice daily
- Estimated price
- €40–65
- Website
- Österreichische Bundesbahnen
Train from Basel SBB to Zürich HB
- Ave. Duration
- 1h 13m
- Frequency
- Every 20 minutes
- Estimated price
- €29–45
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Strasbourg to Massy Tgv
- Ave. Duration
- 3h 1m
- Frequency
- 3 times a day
- Estimated price
- €85–150
- Website
- Oui.SNCF
Train from Bordeaux St Jean to Hendaye
- Ave. Duration
- 2h 39m
- Frequency
- Every 2 hours
- Estimated price
- €40–70
- Website
- Oui.SNCF
Train from Saarbrücken Hbf to Paris Gare de Lyon
- Ave. Duration
- 2h 38m
- Frequency
- Once a week
- Estimated price
- €65–120
- Website
- Oui.SNCF
- Phone
- +34 944 333 333
- [email protected]
- Website
- Euskotren
Train from Amara-Donostia to Zazpikaleak/Casco Viejo-Bilbao
- Ave. Duration
- 2h 31m
- Frequency
- Hourly
- Estimated price
- €5–10
- Website
- Euskotren
- Phone
- +34 91 232 03 20
- Website
- Renfe Viajeros
Train from Bilbao to Santander
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- €8–22
- Website
- Renfe Viajeros
- Phone
- +49 621 830 1200
- Website
- Süwex
Train from Neustadt, Hauptbahnhof to Saarbrücken Hbf
- Ave. Duration
- 1h 13m
- Frequency
- Every 2 hours
- Estimated price
- €18–25
- Schedules at
- Süwex
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Bordeaux to Estación de autobuses de Santander
- Ave. Duration
- 6h 5m
- Frequency
- Once daily
- Estimated price
- €35–60
- Website
- Flixbus
Bus from Paris to Estación de autobuses de Santander
- Ave. Duration
- 12h 50m
- Frequency
- Once daily
- Estimated price
- €85–130
- Website
- Flixbus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Karlsruhe - Central Station South Side to Paris - Bercy-Seine Bus Station
- Ave. Duration
- 7h 50m
- Frequency
- Twice daily
- Estimated price
- €40–70
- Website
- BlaBlaCar Bus
Bus from Saint-Jean-de-Luz to Bilbao Intermodal
- Ave. Duration
- 2h
- Frequency
- Every 4 hours
- Estimated price
- €9–16
- Website
- BlaBlaCar Bus
- Phone
- +34 910 207 007
- Website
- ALSA
Bus from Bilbao Intermodal to Estación de autobuses de Santander
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €8–13
- Website
- ALSA
Bus from Bilbao Intermodal to Estación de autobuses de Santander
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €8–13
- Website
- ALSA
Bus from Bilbao Intermodal to Estación de autobuses de Santander
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €8–13
- Website
- ALSA
Bus from Bilbao Intermodal to Estación de autobuses de Santander
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €8–13
- Website
- ALSA
Bus from Aéroport Orly 4 to Bilbao Intermodal
- Ave. Duration
- 12h 15m
- Frequency
- Once daily
- Estimated price
- €40–120
- Schedules at
- alsa.es
Bus from Bilbao Intermodal to Estación de autobuses de Santander
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €8–13
- Website
- ALSA
Want to know more about travelling around Spain
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Booking & Getting There
Karlsruhe to Santander bus services, operated by BlaBlaCar Bus, arrive at Paris - Bercy-Seine Bus Station.
Karlsruhe to Santander train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Strasbourg Bahnhof station.
Yes, the driving distance between Karlsruhe to Santander is 1415 km. It takes approximately 13h 53m to drive from Karlsruhe to Santander.
Book your Karlsruhe to Santander bus tickets online with Omio.
There are 1980+ hotels available in Santander.
























































