There are 12 ways to get from Karlsruhe to Santander by train, plane, bus, car, or train (TGV, Renfe)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Stuttgart Airport, fly to Santander Airport
best- Take the train from Karlsruhe Hbf to Stuttgart Hbftrain
- Fly from Stuttgart Airport (STR) to Santander Airport (SDR)plane STR - SDR
8h 23m€76–412Fly Karlsruhe/Baden-Baden Airport to Santander Airport
cheapest- Fly from Karlsruhe/Baden-Baden Airport (FKB) to Santander Airport (SDR)plane FKB - SDR
7h 46m€65–270Train, bus via Antony
- Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain 83 / ...
- Take the train from Strasbourg to Massy Tgvtrain Tgv
- Take the train from Massy Tgv to Hendayetrain Tgv
- Take the bus from Irun to Estación de autobuses de Santanderbus
14h 53m€259–432Bus
- Take the bus from Karlsruhe central train station to Strasbourgbus 091 / ...
- Take the bus from Strasbourg - L'Étoile Park Bus Station to Paris - Bercy-Seine Bus Stationbus
- Take the bus from Paris to Estación de autobuses de Santanderbus
21h 54m€115–200Drive 1,415.4 km
- Drive from Karlsruhe to Santandercar 1,415.4 km
13h 53m€231–333Train to Strasbourg International Airport, fly to Santander Airport
- Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain
- Fly from Strasbourg International Airport (SXB) to Santander Airport (SDR)plane SXB - SDR
8h 9m€116–353Train to Stuttgart Airport, fly to Bilbao Airport, bus
- Take the train from Karlsruhe Hbf to Stuttgart Hbftrain
- Fly from Stuttgart Airport (STR) to Bilbao Airport (BIO)plane STR - BIO
- Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus
8h 16m€100–308Train, train to Frankfurt, fly to Bilbao Airport, bus
- Take the train from Karlsruhe Hauptbahnhof to Mannheim, Hauptbahnhoftrain
- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Bilbao Airport (BIO)plane FRA - BIO
- Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus
8h 18m€116–317Train, train to Zurich Airport, fly to Bilbao Airport, bus
- Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain
- Take the train from Basel SBB to Zürich HBtrain
- Fly from Zurich Airport (ZRH) to Bilbao Airport (BIO)plane ZRH - BIO
- Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus
10h 9m€134–356Train, bus
- Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain 83 / ...
- Take the train from Strasbourg to Bordeaux St Jeantrain Tgv
- Take the bus from Bordeaux to Estación de autobuses de Santanderbus
14h 56m€250–385Train
- Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain 83 / ...
- Take the train from Strasbourg to Bordeaux St Jeantrain Tgv
- Take the train from Bordeaux St Jean to Hendayetrain Ter
- Take the train from Amara-Donostia to Zazpikaleak/Casco Viejo-Bilbaotrain E1
- Take the train from Bilbao to Santandertrain
19h 21m€270–436Train, bus #2
- Take the train from Karlsruhe Hauptbahnhof to Neustadt, Hauptbahnhoftrain Re6
- Take the train from Neustadt, Hauptbahnhof to Saarbrücken Hbftrain Re1
- Take the train from Saarbrücken Hbf to Paris Gare de Lyontrain 82
- Take the bus from Aéroport Orly 4 to Bilbao Intermodalbus
- Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus
22h 45m€150–344
Karlsruhe to Santander by train and bus
Comparing Your Travel Options
The cheapest way to get from Karlsruhe to Santander is to fly which costs €65 - €270 and takes 7h 46m.
The fastest way to get from Karlsruhe to Santander is to fly which takes 7h 46m and costs €65 - €270.
No, there is no direct bus from Karlsruhe station to Santander. However, there are services departing from Karlsruhe central train station and arriving at Estación de autobuses de Santander via Strasbourg - L'Étoile Park Bus Station and Paris. The journey, including transfers, takes approximately 21h 54m.
No, there is no direct train from Karlsruhe to Santander. However, there are services departing from Karlsruhe Hauptbahnhof and arriving at Santander via Strasbourg, Bordeaux St Jean, Hendaia, Amara-Donostia and Bilbao. The journey, including transfers, takes approximately 19h 21m.
The distance between Karlsruhe and Santander is 1257 km. The road distance is 1415.4 km.
The best way to get from Karlsruhe to Santander without a car is to train and bus via Antony which takes 14h 53m and costs €250 - €440.
It takes approximately 8h 23m to get from Karlsruhe to Santander, including transfers.
Karlsruhe to Santander bus services, operated by FlixBus, depart from Karlsruhe central train station.
Karlsruhe to Santander train services, operated by Deutsche Bahn Intercity (DB IC), depart from Karlsruhe Hauptbahnhof station.
The best way to get from Karlsruhe to Santander is to bus which takes 21h 54m and costs €110 - €200. Alternatively, you can fly, which costs €65 - €270 and takes 7h 46m, you could also train, which costs €270 - €440 and takes 19h 21m.
What companies run services between Karlsruhe, Germany and Santander, Spain?
You can take a bus from Karlsruhe central train station to Estación de autobuses de Santander via Strasbourg - L'Étoile Park Bus Station, Paris - Bercy-Seine Bus Station, and Paris in around 21h 54m. Alternatively, Ryanair, Volotea, and Vueling Airlines fly from Karlsruhe/Baden-Baden Airport (FKB) to Santander Airport (SDR) 6 times a week.
- Website
- vueling.com
Flights from Stuttgart Airport to Santander Airport via Barcelona
- Ave. Duration
- 8h 7m
- When
- Friday to Saturday
- Estimated price
- €85–440
Flights from Stuttgart Airport to Santander Airport via Alicante–Elche
- Ave. Duration
- 5h
- When
- Monday, Thursday, and Saturday
- Estimated price
- €110–450
Flights from Stuttgart Airport to Santander Airport via Palma Mallorca
- Ave. Duration
- 6h 15m
- When
- Friday
- Estimated price
- €110–450
Flights from Strasbourg International Airport to Santander Airport via Madrid
- Ave. Duration
- 8h 6m
- When
- Monday to Friday
- Estimated price
- €100–500
Flights from Strasbourg International Airport to Santander Airport via Barcelona
- Ave. Duration
- 5h 10m
- When
- Monday and Thursday
- Estimated price
- €120–300
Flights from Karlsruhe/Baden-Baden Airport to Santander Airport via Alicante–Elche
- Ave. Duration
- 5h 35m
- When
- Monday, Thursday, and Saturday
- Estimated price
- €80–270
Flights from Karlsruhe/Baden-Baden Airport to Santander Airport via Palma Mallorca
- Ave. Duration
- 6h 20m
- When
- Monday
- Estimated price
- €80–270
Flights from Stuttgart Airport to Bilbao Airport via Barcelona
- Ave. Duration
- 4h 31m
- When
- Friday, Thursday, Monday, and Wednesday
- Estimated price
- €80–210
Flights from Zurich Airport to Bilbao Airport via Barcelona
- Ave. Duration
- 4h 35m
- When
- Friday
- Estimated price
- €70–210
- Website
- iberia.com
Flights from Stuttgart Airport to Santander Airport via Barcelona
- Ave. Duration
- 8h 7m
- When
- Friday to Saturday
- Estimated price
- €85–440
Flights from Stuttgart Airport to Santander Airport via Alicante–Elche
- Ave. Duration
- 5h
- When
- Monday, Thursday, and Saturday
- Estimated price
- €110–450
Flights from Stuttgart Airport to Santander Airport via Palma Mallorca
- Ave. Duration
- 6h 15m
- When
- Friday
- Estimated price
- €110–450
Flights from Strasbourg International Airport to Santander Airport via Madrid
- Ave. Duration
- 8h 6m
- When
- Monday to Friday
- Estimated price
- €100–500
Flights from Strasbourg International Airport to Santander Airport via Barcelona
- Ave. Duration
- 5h 10m
- When
- Monday and Thursday
- Estimated price
- €120–300
Flights from Karlsruhe/Baden-Baden Airport to Santander Airport via Alicante–Elche
- Ave. Duration
- 5h 35m
- When
- Monday, Thursday, and Saturday
- Estimated price
- €80–270
Flights from Karlsruhe/Baden-Baden Airport to Santander Airport via Palma Mallorca
- Ave. Duration
- 6h 20m
- When
- Monday
- Estimated price
- €80–270
Flights from Stuttgart Airport to Bilbao Airport via Barcelona
- Ave. Duration
- 4h 31m
- When
- Friday, Thursday, Monday, and Wednesday
- Estimated price
- €80–210
Flights from Zurich Airport to Bilbao Airport via Barcelona
- Ave. Duration
- 4h 35m
- When
- Friday
- Estimated price
- €70–210
- Website
- lufthansa.com
Flights from Stuttgart Airport to Bilbao Airport via Munich
- Ave. Duration
- 4h 45m
- When
- Every day
- Estimated price
- €100–370
Flights from Frankfurt to Bilbao Airport
- Ave. Duration
- 2h 10m
- When
- Every day
- Estimated price
- €55–320
Flights from Zurich Airport to Bilbao Airport via Frankfurt
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- €95–330
- Website
- volotea.com
Flights from Stuttgart Airport to Santander Airport via Malaga
- Ave. Duration
- 5h 20m
- When
- Tuesday
- Estimated price
- €110–470
Flights from Karlsruhe/Baden-Baden Airport to Santander Airport via Malaga
- Ave. Duration
- 5h 20m
- When
- Thursday
- Estimated price
- €80–270
- Website
- flyulendo.com
Flights from Stuttgart Airport to Santander Airport via Valencia
- Ave. Duration
- 6h 50m
- When
- Tuesday and Saturday
- Estimated price
- €110–450
Flights from Stuttgart Airport to Santander Airport via Milan Malpensa
- Ave. Duration
- 7h 25m
- When
- Tuesday
- Estimated price
- €60–340
- Website
- ryanair.com
Flights from Karlsruhe/Baden-Baden Airport to Santander Airport via London Stansted
- Ave. Duration
- 4h 30m
- When
- Sunday
- Estimated price
- €80–270
- Website
- eurowings.com
Flights from Stuttgart Airport to Bilbao Airport
- Ave. Duration
- 2h
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €60–210
- Website
- klm.com
Flights from Stuttgart Airport to Bilbao Airport via Amsterdam Schiphol
- Ave. Duration
- 4h 15m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €75–390
- Website
- lufthansa-city.com
Flights from Frankfurt to Bilbao Airport
- Ave. Duration
- 2h 10m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €55–310
- Website
- brusselsairlines.com
Flights from Frankfurt to Bilbao Airport via Brussels
- Ave. Duration
- 4h 30m
- When
- Monday and Sunday
- Estimated price
- €65–260
- Website
- luxair.lu
Flights from Frankfurt to Bilbao Airport via Luxembourg
- Ave. Duration
- 5h 5m
- When
- Thursday and Sunday
- Estimated price
- €90–370
- Website
- flyedelweiss.com
Flights from Zurich Airport to Bilbao Airport
- Ave. Duration
- 1h 50m
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- €50–290
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 47 min
- Frequency
- Hourly
- Estimated price
- €14–29
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhof
- Ave. Duration
- 43 min
- Frequency
- Every 4 hours
- Estimated price
- €15–35
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhof
- Ave. Duration
- 43 min
- Frequency
- Every 4 hours
- Estimated price
- €15–35
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 47 min
- Frequency
- Hourly
- Estimated price
- €14–29
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 23 min
- Frequency
- Hourly
- Estimated price
- €11–22
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Hourly
- Estimated price
- €13–27
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Basel SBB
- Ave. Duration
- 1h 48m
- Frequency
- Hourly
- Estimated price
- €35–75
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhof
- Ave. Duration
- 43 min
- Frequency
- Every 4 hours
- Estimated price
- €15–35
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhof
- Ave. Duration
- 43 min
- Frequency
- Every 4 hours
- Estimated price
- €15–35
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Neustadt, Hauptbahnhof to Saarbrücken Hbf
- Ave. Duration
- 1h 5m
- Frequency
- 4 times a day
- Estimated price
- €18–40
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +49 711 400 534 44
- [email protected]
- Website
- Arverio Baden-Württemberg GmbH
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €13–19
- Schedules at
- Arverio Baden-Württemberg GmbH
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €13–19
- Schedules at
- Arverio Baden-Württemberg GmbH
- Phone
- +49 711 400 534 44
- [email protected]
- Website
- Arverio Baden-Württemberg
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 55 min
- Frequency
- Every 30 minutes
- Estimated price
- €14–26
- Schedules at
- Arverio Baden-Württemberg
- 2nd Class Ticket
- €14–17
- 1st Class Ticket
- €18–26
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 55 min
- Frequency
- Every 30 minutes
- Estimated price
- €14–26
- Schedules at
- Arverio Baden-Württemberg
- 2nd Class Ticket
- €14–17
- 1st Class Ticket
- €18–26
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 47 min
- Frequency
- Every 4 hours
- Estimated price
- €15–23
- Website
- TGV inOui
Train from Strasbourg to Massy Tgv
- Ave. Duration
- 3h 3m
- Frequency
- Every 3 hours
- Estimated price
- €95–150
- Website
- TGV inOui
Train from Massy Tgv to Hendaye
- Ave. Duration
- 4h 40m
- Frequency
- 6 times a week
- Estimated price
- €140–220
- Website
- TGV inOui
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 47 min
- Frequency
- Every 4 hours
- Estimated price
- €15–23
- Website
- TGV inOui
Train from Strasbourg to Bordeaux St Jean
- Ave. Duration
- 6h 1m
- Frequency
- Twice daily
- Estimated price
- €200–300
- Website
- TGV inOui
Train from Strasbourg to Bordeaux St Jean
- Ave. Duration
- 6h 1m
- Frequency
- Twice daily
- Estimated price
- €200–300
- Website
- TGV inOui
Train from Bordeaux St Jean to Hendaye
- Ave. Duration
- 2h 27m
- Frequency
- Every 3 hours
- Estimated price
- €45–70
- Website
- TGV inOui
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 1h 36m
- Frequency
- 5 times a week
- Estimated price
- €13–60
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 1h 36m
- Frequency
- 5 times a week
- Estimated price
- €13–60
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Karlsruhe Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 54 min
- Frequency
- Hourly
- Estimated price
- €10–45
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Karlsruhe Hauptbahnhof to Neustadt, Hauptbahnhof
- Ave. Duration
- 1h 9m
- Frequency
- Hourly
- Estimated price
- €9–45
- Website
- Deutsche Bahn Regio (DB Regional)
Rome2Rio's guide to Société Nationale des Chemins de fer Français (SNCF)
Contact DetailsContact Details
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Strasbourg to Massy Tgv
- Ave. Duration
- 3h 1m
- Frequency
- 3 times a day
- Estimated price
- €85–150
- Website
- Oui.SNCF
Train from Bordeaux St Jean to Hendaye
- Ave. Duration
- 2h 39m
- Frequency
- Every 2 hours
- Estimated price
- €40–70
- Website
- Oui.SNCF
Train from Saarbrücken Hbf to Paris Gare de Lyon
- Ave. Duration
- 2h 38m
- Frequency
- Once a week
- Estimated price
- €65–120
- Website
- Oui.SNCF
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Once daily
- Estimated price
- €7–16
- Website
- Nederlandse Spoorwegen (NS)
Train from Karlsruhe Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 18m
- Frequency
- Twice daily
- Estimated price
- €21–45
- Website
- Nederlandse Spoorwegen (NS)
- Phone
- +43 5 1717
- Website
- Österreichische Bundesbahnen
Train from Karlsruhe Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 17m
- Frequency
- Twice daily
- Estimated price
- €40–65
- Website
- Österreichische Bundesbahnen
Train from Basel SBB to Zürich HB
- Ave. Duration
- 1h 13m
- Frequency
- Every 20 minutes
- Estimated price
- €26–40
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +34 944 333 333
- [email protected]
- Website
- Euskotren
Train from Amara-Donostia to Zazpikaleak/Casco Viejo-Bilbao
- Ave. Duration
- 2h 31m
- Frequency
- Hourly
- Estimated price
- €5–10
- Website
- Euskotren
- Phone
- +34 91 232 03 20
- Website
- Renfe Viajeros
Train from Bilbao to Santander
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- €8–22
- Website
- Renfe Viajeros
- Phone
- +49 621 830 1200
- Website
- Süwex
Train from Neustadt, Hauptbahnhof to Saarbrücken Hbf
- Ave. Duration
- 1h 13m
- Frequency
- Every 2 hours
- Estimated price
- €18–25
- Schedules at
- Süwex
- Phone
- +34 910 207 007
- Website
- ALSA
Bus from Irun to Estación de autobuses de Santander
- Ave. Duration
- 3h 15m
- Frequency
- 5 times a day
- Estimated price
- €18–29
- Website
- ALSA
Bus from Bilbao Intermodal to Estación de autobuses de Santander
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €8–13
- Website
- ALSA
Bus from Bilbao Intermodal to Estación de autobuses de Santander
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €8–13
- Website
- ALSA
Bus from Bilbao Intermodal to Estación de autobuses de Santander
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €8–13
- Website
- ALSA
Bus from Aéroport Orly 4 to Bilbao Intermodal
- Ave. Duration
- 12h 15m
- Frequency
- Once daily
- Estimated price
- €40–120
- Schedules at
- alsa.es
Bus from Bilbao Intermodal to Estación de autobuses de Santander
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €8–13
- Website
- ALSA
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Karlsruhe central train station to Strasbourg
- Ave. Duration
- 1h 20m
- Frequency
- Hourly
- Estimated price
- €6–10
- Website
- Flixbus
Bus from Strasbourg - L'Étoile Park Bus Station to Paris - Bercy-Seine Bus Station
- Ave. Duration
- 6h 5m
- Frequency
- Twice daily
- Estimated price
- €40–60
- Website
- Flixbus
Bus from Paris to Estación de autobuses de Santander
- Ave. Duration
- 12h 50m
- Frequency
- Once daily
- Estimated price
- €80–130
- Website
- Flixbus
Bus from Bordeaux to Estación de autobuses de Santander
- Ave. Duration
- 6h 5m
- Frequency
- Once daily
- Estimated price
- €35–55
- Website
- Flixbus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Karlsruhe central train station to Strasbourg
- Ave. Duration
- 1h 5m
- Frequency
- Every 3 hours
- Estimated price
- €5–9
- Website
- BlaBlaCar Bus
Bus from Strasbourg - L'Étoile Park Bus Station to Paris - Bercy-Seine Bus Station
- Ave. Duration
- 6h
- Frequency
- Hourly
- Estimated price
- €30–55
- Website
- BlaBlaCar Bus
Want to know more about travelling around Spain
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Karlsruhe to Santander bus services, operated by FlixBus, arrive at Strasbourg station.
Karlsruhe to Santander train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Strasbourg Bahnhof station.
Yes, the driving distance between Karlsruhe to Santander is 1415 km. It takes approximately 13h 53m to drive from Karlsruhe to Santander.
Book your Karlsruhe to Santander bus tickets online with Omio and FlixBus.
There are 2003+ hotels available in Santander.
























































