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How to get fromKarlsruhe to Santanderby train, bus, car, or plane

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There are 11 ways to get from Karlsruhe to Santander by train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain train 83 / ...
    2. Take the train from Strasbourg to Bordeaux St Jeantrain train Tgv
    3. Take the bus from Bordeaux to Estación de autobuses de Santanderbus bus
    14h 56m
    €248–374

  2. Fly Karlsruhe/Baden-Baden Airport to Santander Airport

    cheapest
    1. Fly from Karlsruhe/Baden-Baden Airport (FKB) to Santander Airport (SDR)plane plane FKB - SDR
    12h 13m
    €80–270

  3. Bus via Paris

    1. Take the bus from Karlsruhe central train station to Paris, Quai de Bercy (Bercy Seine)bus bus N91 / ...
    2. Take the bus from Paris, Quai de Bercy (Bercy Seine) to Santanderbus bus 7783
    20h 50m
    €136–205

  4. Drive  1,415.4 km

    1. Drive from Karlsruhe to Santandercar car 1,415.4 km
    13h 53m
    €255–368

  5. Train to Stuttgart Airport, fly to Santander Airport

    1. Take the train from Karlsruhe Hbf to Stuttgart Hbftrain train
    2. Fly from Stuttgart Airport (STR) to Santander Airport (SDR)plane plane STR - SDR
    11h 14m
    €85–359

  6. Train, bus via Antony

    1. Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain train 83 / ...
    2. Take the train from Strasbourg to Massy Tgvtrain train Tgv
    3. Take the train from Massy Tgv to Hendayetrain train Tgv
    4. Take the bus from Estación de Autobuses Donostia-San Sebastián to Santanderbus bus
    14h 57m
    €267–414

  7. Bus

    1. Take the bus from Karlsruhe central train station to Metzbus bus
    2. Take the bus from Metz - Bus Station to Bilbao Intermodalbus bus
    3. Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus bus
    24h 28m
    €122–215

  8. Train to Strasbourg International Airport, fly to Santander Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain train
    2. Fly from Strasbourg International Airport (SXB) to Santander Airport (SDR)plane plane SXB - SDR
    8h 9m
    €104–357

  9. Train to Stuttgart Airport, fly to Bilbao Airport, bus

    1. Take the train from Karlsruhe Hbf to Stuttgart Hbftrain train
    2. Fly from Stuttgart Airport (STR) to Bilbao Airport (BIO)plane plane STR - BIO
    3. Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus bus
    8h 8m
    €94–275

  10. Train to Frankfurt, fly to Bilbao Airport, bus

    1. Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Bilbao Airport (BIO)plane plane FRA - BIO
    3. Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus bus
    8h 8m
    €110–295

  11. Train, train to Zurich Airport, fly to Bilbao Airport, bus

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train
    2. Take the train from Basel SBB to Zürich HBtrain train
    3. Fly from Zurich Airport (ZRH) to Bilbao Airport (BIO)plane plane ZRH - BIO
    4. Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus bus
    10h 5m
    €147–389

Karlsruhe to Santander by train, foot, and bus

Calendar7Weekly Services
Duration14h 56mAverage Duration
Ticket€248Cheapest Price
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Comparing Your Travel Options

Map of how to get from Karlsruhe to Santander.ExpandLaunch map view
  • Distance: 1,545.5 km
  • Duration: 14h 56m

What companies run services between Karlsruhe, Germany and Santander, Spain?

You can take a bus from Karlsruhe central train station to Santander via Paris, Quai de Bercy (Bercy Seine) in around 20h 50m. Alternatively, Ryanair, Vueling Airlines, and Volotea fly from Karlsruhe/Baden-Baden Airport (FKB) to Santander Airport (SDR) once daily.

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