There are 12 ways to get from Karlsruhe to Santander by train, bus, car, plane, or train (TGV, Renfe)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain 83 / ...
- Take the train from Strasbourg to Bordeaux St Jeantrain Tgv
- Take the bus from Bordeaux to Estación de autobuses de Santanderbus
14h 56m€249–401Fly Karlsruhe/Baden-Baden Airport to Santander Airport
cheapest- Fly from Karlsruhe/Baden-Baden Airport (FKB) to Santander Airport (SDR)plane FKB - SDR
9h 21m€65–270Bus
- Take the bus from Karlsruhe - Central Station South Side to Paris - Bercy-Seine Bus Stationbus BlaBlaCar Bus
- Take the bus from Paris to Estación de autobuses de Santanderbus FlixBus 783
21h 40m€128–200Drive 1,415.4 km
- Drive from Karlsruhe to Santandercar 1,415.4 km
13h 53m€231–334Train, bus via Antony
- Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain 83 / ...
- Take the train from Strasbourg to Massy Tgvtrain Tgv
- Take the train from Massy Tgv to St Jean De Luz Cibouretrain Tgv
- Take the bus from Saint-Jean-de-Luz to Bilbao Intermodalbus
- Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus
15h 18m€267–431Train
- Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain 83 / ...
- Take the train from Strasbourg to Bordeaux St Jeantrain Tgv
- Take the train from Bordeaux St Jean to Hendayetrain Ter
- Take the train from Amara-Donostia to Zazpikaleak/Casco Viejo-Bilbaotrain E1
- Take the train from Bilbao to Santandertrain
19h 20m€269–447Train, bus via Paris Orly Airport (ORY)
- Take the train from Karlsruhe Hauptbahnhof to Neustadt, Hauptbahnhoftrain Re6
- Take the train from Neustadt, Hauptbahnhof to Saarbrücken Hbftrain Re1
- Take the train from Saarbrücken Hbf to Paris Gare de Lyontrain 82
- Take the bus from Aéroport Orly 4 to Bilbao Intermodalbus
- Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus
22h 45m€150–346Train to Stuttgart Airport, fly to Bilbao Airport, bus
- Take the train from Karlsruhe Hbf to Stuttgart Hbftrain
- Fly from Stuttgart Airport (STR) to Bilbao Airport (BIO)plane STR - BIO
- Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus
8h 24m€96–312Train to Frankfurt, fly to Bilbao Airport, bus
- Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Bilbao Airport (BIO)plane FRA - BIO
- Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus
8h 12m€122–295Train to Stuttgart Airport, fly to Santander Airport
- Take the train from Karlsruhe Hbf to Stuttgart Hbftrain
- Fly from Stuttgart Airport (STR) to Santander Airport (SDR)plane STR - SDR
8h 51m€102–446Train to Basel, fly to Bilbao Airport, bus
- Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain
- Fly from Basel (BSL) to Bilbao Airport (BIO)plane BSL - BIO
- Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus
8h 59m€101–310Train, train to Zurich Airport, fly to Bilbao Airport, bus
- Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain
- Take the train from Basel SBB to Zürich HBtrain
- Fly from Zurich Airport (ZRH) to Bilbao Airport (BIO)plane ZRH - BIO
- Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus
10h 9m€138–383
Karlsruhe to Santander by train, foot, and bus
Comparing Your Travel Options
The cheapest way to get from Karlsruhe to Santander is to fly which costs €65 - €270 and takes 9h 21m.
The fastest way to get from Karlsruhe to Santander is to train and fly and bus which takes 8h 12m and costs €120 - €300.
No, there is no direct bus from Karlsruhe station to Santander. However, there are services departing from Karlsruhe - Central Station South Side and arriving at Estación de autobuses de Santander via Paris. The journey, including transfers, takes approximately 21h 40m.
No, there is no direct train from Karlsruhe to Santander. However, there are services departing from Karlsruhe Hauptbahnhof and arriving at Santander via Strasbourg, Bordeaux St Jean, Hendaia, Amara-Donostia and Bilbao. The journey, including transfers, takes approximately 19h 20m.
The distance between Karlsruhe and Santander is 1546 km. The road distance is 1415.4 km.
The best way to get from Karlsruhe to Santander without a car is to train and bus which takes 14h 56m and costs €240 - €410.
It takes approximately 14h 56m to get from Karlsruhe to Santander, including transfers.
Karlsruhe to Santander bus services, operated by BlaBlaCar Bus, depart from Karlsruhe - Central Station South Side.
Karlsruhe to Santander train services, operated by Deutsche Bahn Intercity (DB IC), depart from Karlsruhe Hauptbahnhof station.
The best way to get from Karlsruhe to Santander is to bus which takes 21h 40m and costs €120 - €200. Alternatively, you can fly, which costs €65 - €270 and takes 9h 21m, you could also train, which costs €260 - €450 and takes 19h 20m.
What companies run services between Karlsruhe, Germany and Santander, Spain?
You can take a bus from Karlsruhe - Central Station South Side to Estación de autobuses de Santander via Paris - Bercy-Seine Bus Station and Paris in around 21h 40m. Alternatively, Ryanair, Volotea, and two other airlines fly from Karlsruhe/Baden-Baden Airport (FKB) to Santander Airport (SDR) once daily.
- Website
- lufthansa.com
Flights from Stuttgart Airport to Bilbao Airport via Munich
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- €100–370
Flights from Frankfurt to Bilbao Airport
- Ave. Duration
- 2h 10m
- When
- Every day
- Estimated price
- €55–320
Flights from Basel to Bilbao Airport via Munich
- Ave. Duration
- 4h 45m
- When
- Monday, Friday, and Sunday
- Estimated price
- €100–370
Flights from Zurich Airport to Bilbao Airport via Frankfurt
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- €90–320
- Website
- vueling.com
Flights from Karlsruhe/Baden-Baden Airport to Santander Airport via Alicante–Elche
- Ave. Duration
- 12h 20m
- When
- Saturday
- Estimated price
- €80–270
Flights from Stuttgart Airport to Bilbao Airport via Barcelona
- Ave. Duration
- 4h 38m
- When
- Saturday, Friday, Monday, and Sunday
- Estimated price
- €80–210
Flights from Stuttgart Airport to Santander Airport via Barcelona
- Ave. Duration
- 6h 30m
- When
- Tuesday
- Estimated price
- €85–370
Flights from Zurich Airport to Bilbao Airport via Barcelona
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- €70–210
- Website
- ryanair.com
Flights from Karlsruhe/Baden-Baden Airport to Santander Airport via London Stansted
- Ave. Duration
- 12h 25m
- When
- Monday, Sunday, Saturday, and Friday
- Estimated price
- €80–270
- Website
- volotea.com
Flights from Karlsruhe/Baden-Baden Airport to Santander Airport via Valencia
- Ave. Duration
- 6h 5m
- When
- Tuesday
- Estimated price
- €80–270
Flights from Stuttgart Airport to Santander Airport via Malaga
- Ave. Duration
- 5h 22m
- When
- Tuesday and Saturday
- Estimated price
- €110–460
- Website
- klm.com
Flights from Stuttgart Airport to Bilbao Airport via Amsterdam Schiphol
- Ave. Duration
- 4h 35m
- When
- Every day
- Estimated price
- €75–390
- Website
- ryanair.com
Flights from Karlsruhe/Baden-Baden Airport to Santander Airport via London Stansted
- Ave. Duration
- 11h 25m
- When
- Monday
- Estimated price
- €85–350
- Website
- eurowings.com
Flights from Stuttgart Airport to Bilbao Airport
- Ave. Duration
- 2h
- When
- Friday
- Estimated price
- €60–210
- Website
- lufthansa-city.com
Flights from Frankfurt to Bilbao Airport
- Ave. Duration
- 2h 10m
- When
- Monday, Friday, and Saturday
- Estimated price
- €55–300
- Website
- luxair.lu
Flights from Frankfurt to Bilbao Airport via Luxembourg
- Ave. Duration
- 5h 15m
- When
- Thursday and Sunday
- Estimated price
- €90–370
- Website
- easyjet.com
Flights from Basel to Bilbao Airport
- Ave. Duration
- 1h 55m
- When
- Monday and Friday
- Estimated price
- €70–210
- Website
- flyedelweiss.com
Flights from Zurich Airport to Bilbao Airport
- Ave. Duration
- 1h 50m
- When
- Tuesday, Thursday, and Sunday
- Estimated price
- €50–280
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhof
- Ave. Duration
- 43 min
- Frequency
- Every 4 hours
- Estimated price
- €14–35
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhof
- Ave. Duration
- 43 min
- Frequency
- Every 4 hours
- Estimated price
- €14–35
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhof
- Ave. Duration
- 43 min
- Frequency
- Every 4 hours
- Estimated price
- €14–35
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Neustadt, Hauptbahnhof to Saarbrücken Hbf
- Ave. Duration
- 1h 5m
- Frequency
- 4 times a day
- Estimated price
- €17–40
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 47 min
- Frequency
- Every 3 hours
- Estimated price
- €14–30
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Frankfurt
- Ave. Duration
- 1h 9m
- Frequency
- Every 4 hours
- Estimated price
- €23–50
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 47 min
- Frequency
- Every 3 hours
- Estimated price
- €14–30
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Basel SBB
- Ave. Duration
- 1h 48m
- Frequency
- Hourly
- Estimated price
- €30–75
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Basel SBB
- Ave. Duration
- 1h 48m
- Frequency
- Hourly
- Estimated price
- €30–75
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Strasbourg to Bordeaux St Jean
- Ave. Duration
- 6h 1m
- Frequency
- Twice daily
- Estimated price
- €200–310
- Website
- TGV inOui
Train from Strasbourg to Massy Tgv
- Ave. Duration
- 3h 3m
- Frequency
- Every 3 hours
- Estimated price
- €100–150
- Website
- TGV inOui
Train from Massy Tgv to St Jean De Luz Ciboure
- Ave. Duration
- 4h 24m
- Frequency
- 6 times a week
- Estimated price
- €150–220
- Website
- TGV inOui
Train from Strasbourg to Bordeaux St Jean
- Ave. Duration
- 6h 1m
- Frequency
- Twice daily
- Estimated price
- €200–310
- Website
- TGV inOui
Train from Bordeaux St Jean to Hendaye
- Ave. Duration
- 2h 27m
- Frequency
- Every 3 hours
- Estimated price
- €45–70
- Website
- TGV inOui
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 37 min
- Frequency
- 3 times a day
- Estimated price
- €16–24
- Website
- TGV inOui
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 37 min
- Frequency
- 3 times a day
- Estimated price
- €16–24
- Website
- TGV inOui
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Strasbourg to Massy Tgv
- Ave. Duration
- 3h 1m
- Frequency
- 3 times a day
- Estimated price
- €85–150
- Website
- Oui.SNCF
Train from Bordeaux St Jean to Hendaye
- Ave. Duration
- 2h 39m
- Frequency
- Every 2 hours
- Estimated price
- €40–70
- Website
- Oui.SNCF
Train from Saarbrücken Hbf to Paris Gare de Lyon
- Ave. Duration
- 2h 38m
- Frequency
- Once a week
- Estimated price
- €65–120
- Website
- Oui.SNCF
- Phone
- +34 944 333 333
- [email protected]
- Website
- Euskotren
Train from Amara-Donostia to Zazpikaleak/Casco Viejo-Bilbao
- Ave. Duration
- 2h 31m
- Frequency
- Hourly
- Estimated price
- €5–10
- Website
- Euskotren
- Phone
- +34 91 232 03 20
- Website
- Renfe Viajeros
Train from Bilbao to Santander
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- €8–22
- Website
- Renfe Viajeros
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Karlsruhe Hauptbahnhof to Neustadt, Hauptbahnhof
- Ave. Duration
- 1h 9m
- Frequency
- Hourly
- Estimated price
- €10–45
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 1h 36m
- Frequency
- 5 times a week
- Estimated price
- €15–65
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 1h 36m
- Frequency
- 5 times a week
- Estimated price
- €15–65
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +49 621 830 1200
- Website
- Süwex
Train from Neustadt, Hauptbahnhof to Saarbrücken Hbf
- Ave. Duration
- 1h 13m
- Frequency
- Every 2 hours
- Estimated price
- €18–25
- Schedules at
- Süwex
- Phone
- +49 711 400 534 44
- [email protected]
- Website
- Arverio Baden-Württemberg
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €14–27
- Schedules at
- Arverio Baden-Württemberg
- 2nd Class Ticket
- €14–18
- 1st Class Ticket
- €18–27
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €14–27
- Schedules at
- Arverio Baden-Württemberg
- 2nd Class Ticket
- €14–18
- 1st Class Ticket
- €18–27
- Phone
- +49 711 400 534 44
- [email protected]
- Website
- Arverio Baden-Württemberg GmbH
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €14–20
- Schedules at
- Arverio Baden-Württemberg GmbH
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €14–20
- Schedules at
- Arverio Baden-Württemberg GmbH
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Karlsruhe Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 18m
- Frequency
- Twice daily
- Estimated price
- €21–45
- Website
- Nederlandse Spoorwegen (NS)
Train from Karlsruhe Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 18m
- Frequency
- Twice daily
- Estimated price
- €21–45
- Website
- Nederlandse Spoorwegen (NS)
- Phone
- +43 5 1717
- Website
- Österreichische Bundesbahnen
Train from Karlsruhe Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 17m
- Frequency
- Twice daily
- Estimated price
- €40–65
- Website
- Österreichische Bundesbahnen
Train from Karlsruhe Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 17m
- Frequency
- Twice daily
- Estimated price
- €40–65
- Website
- Österreichische Bundesbahnen
Train from Basel SBB to Zürich HB
- Ave. Duration
- 1h 13m
- Frequency
- Every 20 minutes
- Estimated price
- €30–55
- Website
- Swiss Federal Railways (SBB CFF FFS)
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Bordeaux to Estación de autobuses de Santander
- Ave. Duration
- 6h 5m
- Frequency
- Once daily
- Estimated price
- €35–60
- Website
- Flixbus
Bus from Paris to Estación de autobuses de Santander
- Ave. Duration
- 12h 50m
- Frequency
- Once daily
- Estimated price
- €85–130
- Website
- Flixbus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Karlsruhe - Central Station South Side to Paris - Bercy-Seine Bus Station
- Ave. Duration
- 7h 50m
- Frequency
- Twice daily
- Estimated price
- €40–70
- Website
- BlaBlaCar Bus
Bus from Saint-Jean-de-Luz to Bilbao Intermodal
- Ave. Duration
- 2h
- Frequency
- Every 4 hours
- Estimated price
- €10–17
- Website
- BlaBlaCar Bus
- Phone
- +34 910 207 007
- Website
- ALSA
Bus from Bilbao Intermodal to Estación de autobuses de Santander
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €8–13
- Website
- ALSA
Bus from Aéroport Orly 4 to Bilbao Intermodal
- Ave. Duration
- 12h 15m
- Frequency
- Once daily
- Estimated price
- €40–120
- Schedules at
- alsa.es
Bus from Bilbao Intermodal to Estación de autobuses de Santander
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €8–13
- Website
- ALSA
Bus from Bilbao Intermodal to Estación de autobuses de Santander
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €8–13
- Website
- ALSA
Bus from Bilbao Intermodal to Estación de autobuses de Santander
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €8–13
- Website
- ALSA
Bus from Bilbao Intermodal to Estación de autobuses de Santander
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €8–13
- Website
- ALSA
Bus from Bilbao Intermodal to Estación de autobuses de Santander
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €8–13
- Website
- ALSA
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Booking & Getting There
Karlsruhe to Santander bus services, operated by BlaBlaCar Bus, arrive at Paris - Bercy-Seine Bus Station.
Karlsruhe to Santander train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Strasbourg Bahnhof station.
Yes, the driving distance between Karlsruhe to Santander is 1415 km. It takes approximately 13h 53m to drive from Karlsruhe to Santander.
Book your Karlsruhe to Santander bus tickets online with Omio.
There are 1923+ hotels available in Santander.

























































