There are 12 ways to get from Karlsruhe to Santander by train, bus, car, plane, or train (TGV, Renfe)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain 83 / ...
- Take the train from Strasbourg to Bordeaux St Jeantrain Tgv
- Take the bus from Bordeaux to Estación de autobuses de Santanderbus
14h 56m€248–398Fly Karlsruhe/Baden-Baden Airport to Santander Airport
cheapest- Fly from Karlsruhe/Baden-Baden Airport (FKB) to Santander Airport (SDR)plane FKB - SDR
15h 3m€80–270Bus via Paris
- Take the bus from Karlsruhe central train station to Paris, Quai de Bercy (Bercy Seine)bus N91 / ...
- Take the bus from Paris to Estación de autobuses de Santanderbus FlixBus 783
21h 5m€136–204Drive 1,415.4 km
- Drive from Karlsruhe to Santandercar 1,415.4 km
13h 53m€263–380Train to Stuttgart Airport, fly to Santander Airport
- Take the train from Karlsruhe Hbf to Stuttgart Hbftrain
- Fly from Stuttgart Airport (STR) to Santander Airport (SDR)plane STR - SDR
11h 14m€91–389Train, bus via Antony
- Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain 83 / ...
- Take the train from Strasbourg to Massy Tgvtrain Tgv
- Take the train from Massy Tgv to St Jean De Luz Cibouretrain Tgv
- Take the bus from Saint-Jean-de-Luz to Bilbao Intermodalbus
- Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus
15h 12m€271–439Train
- Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain 83 / ...
- Take the train from Strasbourg to Bordeaux St Jeantrain Tgv
- Take the train from Bordeaux St Jean to Hendayetrain Ter
- Take the train from Amara-Donostia to Zazpikaleak/Casco Viejo-Bilbaotrain E1 / ...
- Take the train from Bilbao to Santandertrain
20h 18m€268–443Bus
- Take the bus from Karlsruhe central train station to Metzbus
- Take the bus from Metz - Bus Station to Bilbao Intermodalbus
- Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus
24h 28m€128–205Train to Strasbourg International Airport, fly to Santander Airport
- Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain
- Fly from Strasbourg International Airport (SXB) to Santander Airport (SDR)plane SXB - SDR
8h 15m€104–361Train to Stuttgart Airport, fly to Bilbao Airport, bus
- Take the train from Karlsruhe Hbf to Stuttgart Hbftrain
- Fly from Stuttgart Airport (STR) to Bilbao Airport (BIO)plane STR - BIO
- Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus
8h 8m€90–275Train to Frankfurt, fly to Bilbao Airport, bus
- Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Bilbao Airport (BIO)plane FRA - BIO
- Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus
8h 8m€111–300Train, train to Zurich Airport, fly to Bilbao Airport, bus
- Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain
- Take the train from Basel SBB to Zürich HBtrain
- Fly from Zurich Airport (ZRH) to Bilbao Airport (BIO)plane ZRH - BIO
- Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus
10h 5m€138–399
Karlsruhe to Santander by train, foot, and bus
Comparing Your Travel Options
The cheapest way to get from Karlsruhe to Santander is to fly which costs €80 - €270 and takes 15h 3m.
The fastest way to get from Karlsruhe to Santander is to train and fly and bus which takes 8h 8m and costs €110 - €300.
No, there is no direct bus from Karlsruhe station to Santander. However, there are services departing from Karlsruhe central train station and arriving at Estación de autobuses de Santander via Paris. The journey, including transfers, takes approximately 21h 5m.
No, there is no direct train from Karlsruhe to Santander. However, there are services departing from Karlsruhe Hauptbahnhof and arriving at Santander via Strasbourg, Bordeaux St Jean, Hendaia, Amara-Donostia and Bilbao. The journey, including transfers, takes approximately 20h 18m.
The distance between Karlsruhe and Santander is 1546 km. The road distance is 1415.4 km.
The best way to get from Karlsruhe to Santander without a car is to train and bus which takes 14h 56m and costs €240 - €400.
It takes approximately 14h 56m to get from Karlsruhe to Santander, including transfers.
Karlsruhe to Santander bus services, operated by FlixBus, depart from Karlsruhe central train station.
Karlsruhe to Santander train services, operated by Deutsche Bahn Intercity (DB IC), depart from Karlsruhe Hauptbahnhof station.
The best way to get from Karlsruhe to Santander is to bus via Paris which takes 21h 5m and costs €130 - €210. Alternatively, you can train, which costs €260 - €450 and takes 20h 18m, you could also fly, which costs €80 - €270 and takes 15h 3m.
What companies run services between Karlsruhe, Germany and Santander, Spain?
You can take a bus from Karlsruhe central train station to Estación de autobuses de Santander via Paris, Quai de Bercy (Bercy Seine) and Paris in around 21h 5m. Alternatively, you can take a train from Karlsruhe Hauptbahnhof to Santander via Strasbourg Bahnhof, Strasbourg, Bordeaux St Jean, Hendaye, Hendaia, Amara-Donostia, Zazpikaleak/Casco Viejo-Bilbao, and Bilbao in around 20h 18m.
- Website
- vueling.com
Flights from Stuttgart Airport to Santander Airport via Barcelona
- Ave. Duration
- 12h 50m
- When
- Monday, Wednesday, Friday, and Sunday
- Estimated price
- €80–410
Flights from Stuttgart Airport to Santander Airport via Madrid
- Ave. Duration
- 13h
- When
- Monday
- Estimated price
- €100–410
Flights from Stuttgart Airport to Santander Airport via Palma Mallorca
- Ave. Duration
- 14h 15m
- When
- Thursday
- Estimated price
- €100–420
Flights from Strasbourg International Airport to Santander Airport via Madrid
- Ave. Duration
- 7h 10m
- When
- Monday to Friday
- Estimated price
- €90–480
Flights from Karlsruhe/Baden-Baden Airport to Santander Airport via Alicante–Elche
- Ave. Duration
- 12h 5m
- When
- Thursday
- Estimated price
- €90–270
Flights from Stuttgart Airport to Bilbao Airport via Barcelona
- Ave. Duration
- 4h 50m
- When
- Monday and Sunday
- Estimated price
- €80–210
Flights from Zurich Airport to Bilbao Airport via Barcelona
- Ave. Duration
- 4h 10m
- When
- Tuesday, Wednesday, Saturday, Monday, Friday, and Sunday
- Estimated price
- €70–200
- Website
- iberia.com
Flights from Stuttgart Airport to Santander Airport via Barcelona
- Ave. Duration
- 12h 50m
- When
- Monday, Wednesday, Friday, and Sunday
- Estimated price
- €80–410
Flights from Stuttgart Airport to Santander Airport via Madrid
- Ave. Duration
- 13h
- When
- Monday
- Estimated price
- €100–410
Flights from Stuttgart Airport to Santander Airport via Palma Mallorca
- Ave. Duration
- 14h 15m
- When
- Thursday
- Estimated price
- €100–420
Flights from Strasbourg International Airport to Santander Airport via Madrid
- Ave. Duration
- 7h 10m
- When
- Monday to Friday
- Estimated price
- €90–480
Flights from Karlsruhe/Baden-Baden Airport to Santander Airport via Alicante–Elche
- Ave. Duration
- 12h 5m
- When
- Thursday
- Estimated price
- €90–270
Flights from Stuttgart Airport to Bilbao Airport via Barcelona
- Ave. Duration
- 4h 50m
- When
- Monday and Sunday
- Estimated price
- €80–210
Flights from Zurich Airport to Bilbao Airport via Barcelona
- Ave. Duration
- 4h 10m
- When
- Tuesday, Wednesday, Saturday, Monday, Friday, and Sunday
- Estimated price
- €70–200
- Website
- lufthansa.com
Flights from Stuttgart Airport to Bilbao Airport via Munich
- Ave. Duration
- 4h 32m
- When
- Every day
- Estimated price
- €100–360
Flights from Frankfurt to Bilbao Airport
- Ave. Duration
- 2h 10m
- When
- Every day
- Estimated price
- €55–310
Flights from Zurich Airport to Bilbao Airport via Frankfurt
- Ave. Duration
- 4h 26m
- When
- Every day
- Estimated price
- €60–300
- Website
- ryanair.com
Flights from Karlsruhe/Baden-Baden Airport to Santander Airport via London Stansted
- Ave. Duration
- 13h 35m
- When
- Sunday, Friday, and Tuesday
- Estimated price
- €90–270
- Website
- klm.com
Flights from Stuttgart Airport to Bilbao Airport via Amsterdam Schiphol
- Ave. Duration
- 4h 35m
- When
- Every day
- Estimated price
- €75–380
- Website
- volotea.com
Flights from Karlsruhe/Baden-Baden Airport to Santander Airport via Sevilla
- Ave. Duration
- 12h 20m
- When
- Thursday and Sunday
- Estimated price
- €90–270
- Website
- eurowings.com
Flights from Stuttgart Airport to Bilbao Airport
- Ave. Duration
- 2h 5m
- When
- Monday and Friday
- Estimated price
- €60–220
- Website
- lufthansa-city.com
Flights from Frankfurt to Bilbao Airport
- Ave. Duration
- 2h 10m
- When
- Every day
- Estimated price
- €55–300
- Website
- flyedelweiss.com
Flights from Zurich Airport to Bilbao Airport
- Ave. Duration
- 1h 50m
- When
- Tuesday, Thursday, and Sunday
- Estimated price
- €45–270
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhof
- Ave. Duration
- 43 min
- Frequency
- Every 3 hours
- Estimated price
- €13–28
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 38 min
- Frequency
- Every 2 hours
- Estimated price
- €12–27
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhof
- Ave. Duration
- 43 min
- Frequency
- Every 3 hours
- Estimated price
- €13–28
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhof
- Ave. Duration
- 43 min
- Frequency
- Every 3 hours
- Estimated price
- €13–28
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhof
- Ave. Duration
- 43 min
- Frequency
- Every 3 hours
- Estimated price
- €13–28
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 38 min
- Frequency
- Every 2 hours
- Estimated price
- €12–27
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Frankfurt
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- €21–45
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Basel SBB
- Ave. Duration
- 1h 48m
- Frequency
- Hourly
- Estimated price
- €30–65
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Strasbourg to Bordeaux St Jean
- Ave. Duration
- 6h 1m
- Frequency
- Once daily
- Estimated price
- €200–310
- Website
- TGV inOui
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 38 min
- Frequency
- 3 times a day
- Estimated price
- €15–24
- Website
- TGV inOui
Train from Strasbourg to Massy Tgv
- Ave. Duration
- 3h 1m
- Frequency
- 4 times a day
- Estimated price
- €100–150
- Website
- TGV inOui
Train from Massy Tgv to St Jean De Luz Ciboure
- Ave. Duration
- 4h 24m
- Frequency
- 3 times a week
- Estimated price
- €150–230
- Website
- TGV inOui
Train from Strasbourg to Bordeaux St Jean
- Ave. Duration
- 6h 1m
- Frequency
- Once daily
- Estimated price
- €200–310
- Website
- TGV inOui
Train from Bordeaux St Jean to Hendaye
- Ave. Duration
- 2h 27m
- Frequency
- 4 times a day
- Estimated price
- €45–70
- Website
- TGV inOui
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 38 min
- Frequency
- 3 times a day
- Estimated price
- €15–24
- Website
- TGV inOui
- Phone
- +49 711 400 534 44
- [email protected]
- Website
- Arverio Baden-Württemberg GmbH
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €13–19
- Schedules at
- Arverio Baden-Württemberg GmbH
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €13–19
- Schedules at
- Arverio Baden-Württemberg GmbH
- Phone
- +49 711 400 534 44
- [email protected]
- Website
- Arverio Baden-Württemberg
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €14–26
- Schedules at
- Arverio Baden-Württemberg
- 2nd Class Ticket
- €14–17
- 1st Class Ticket
- €18–26
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €14–26
- Schedules at
- Arverio Baden-Württemberg
- 2nd Class Ticket
- €14–17
- 1st Class Ticket
- €18–26
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 1h 36m
- Frequency
- 5 times a week
- Estimated price
- €8–13
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Karlsruhe Hbf to Stuttgart Hbf
- Ave. Duration
- 1h 36m
- Frequency
- 5 times a week
- Estimated price
- €8–13
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Karlsruhe Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 43m
- Frequency
- 5 times a week
- Estimated price
- €21–30
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Strasbourg to Massy Tgv
- Ave. Duration
- 3h 1m
- Frequency
- 3 times a day
- Estimated price
- €90–150
- Website
- Oui.SNCF
Train from Bordeaux St Jean to Hendaye
- Ave. Duration
- 2h 39m
- Frequency
- Every 4 hours
- Estimated price
- €40–70
- Website
- Oui.SNCF
- Phone
- +34 944 333 333
- [email protected]
- Website
- Euskotren
Train from Amara-Donostia to Zazpikaleak/Casco Viejo-Bilbao
- Ave. Duration
- 2h 31m
- Frequency
- Hourly
- Estimated price
- €5–10
- Website
- Euskotren
- Phone
- +34 91 232 03 20
- Website
- Renfe Viajeros
Train from Bilbao to Santander
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- €8–21
- Website
- Renfe Viajeros
- Phone
- +43 5 1717
- Website
- Österreichische Bundesbahnen
Train from Karlsruhe Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 17m
- Frequency
- Twice daily
- Estimated price
- €40–65
- Website
- Österreichische Bundesbahnen
Train from Karlsruhe Hauptbahnhof to Basel SBB
- Ave. Duration
- 1h 47m
- Frequency
- 6 times a week
- Estimated price
- €60–100
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Basel SBB to Zürich HB
- Ave. Duration
- 1h 13m
- Frequency
- Every 20 minutes
- Estimated price
- €29–45
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +43 (0) 5 1717
- Website
- ÖBB EuroCity
Train from Karlsruhe Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 12m
- Frequency
- Once a week
- Estimated price
- €50
- Website
- ÖBB EuroCity
- Website
- ÖBB EuroCity
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Bordeaux to Estación de autobuses de Santander
- Ave. Duration
- 6h 5m
- Frequency
- 5 times a week
- Estimated price
- €35–60
- Website
- Flixbus
Bus from Karlsruhe central train station to Paris, Quai de Bercy (Bercy Seine)
- Ave. Duration
- 7h 15m
- Frequency
- Every 3 hours
- Estimated price
- €50–75
- Website
- Flixbus
Bus from Paris to Estación de autobuses de Santander
- Ave. Duration
- 12h 50m
- Frequency
- 5 times a week
- Estimated price
- €85–130
- Website
- Flixbus
Bus from Saint-Jean-de-Luz to Bilbao Intermodal
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- €11–18
- Website
- Flixbus
Bus from Karlsruhe central train station to Metz
- Ave. Duration
- 3h 25m
- Frequency
- Every 4 hours
- Estimated price
- €21–35
- Website
- Flixbus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Saint-Jean-de-Luz to Bilbao Intermodal
- Ave. Duration
- 2h
- Frequency
- 3 times a day
- Estimated price
- €10–18
- Website
- BlaBlaCar Bus
Bus from Karlsruhe central train station to Metz
- Ave. Duration
- 3h 5m
- Frequency
- Twice daily
- Estimated price
- €19–35
- Website
- BlaBlaCar Bus
Bus from Metz - Bus Station to Bilbao Intermodal
- Ave. Duration
- 17h 59m
- Frequency
- Once daily
- Estimated price
- €100–160
- Website
- BlaBlaCar Bus
- Phone
- +34 910 207 007
- Website
- ALSA
Bus from Bilbao Intermodal to Estación de autobuses de Santander
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €8–13
- Website
- ALSA
Bus from Bilbao Intermodal to Estación de autobuses de Santander
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €8–13
- Website
- ALSA
Bus from Bilbao Intermodal to Estación de autobuses de Santander
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €8–13
- Website
- ALSA
Bus from Bilbao Intermodal to Estación de autobuses de Santander
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €8–13
- Website
- ALSA
Bus from Bilbao Intermodal to Estación de autobuses de Santander
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €8–13
- Website
- ALSA
Want to know more about travelling around Spain
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Booking & Getting There
Karlsruhe to Santander bus services, operated by FlixBus, arrive at Paris, Quai de Bercy (Bercy Seine) station.
Karlsruhe to Santander train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Strasbourg Bahnhof station.
Yes, the driving distance between Karlsruhe to Santander is 1415 km. It takes approximately 13h 53m to drive from Karlsruhe to Santander.
Book your Karlsruhe to Santander bus tickets online with Omio, FlixBus and 12go.asia.
There are 1880+ hotels available in Santander.























































