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How to get fromKarlsruhe to Sicilyby train, plane, bus, car, car ferry, or night train

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There are 13 ways to get from Karlsruhe to Sicily by train, plane, bus, car, car ferry, or night train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Stuttgart Airport, fly to Catania–Fontanarossa Airport

    best
    1. Take the train from Karlsruhe Hbf to Stuttgart Hbftrain train
    2. Fly from Stuttgart Airport (STR) to Catania–Fontanarossa Airport (CTA)plane plane STR - CTA
    6h
    €90–316

  2. Fly Karlsruhe/Baden-Baden Airport to Trapani Airport

    cheapest
    1. Fly from Karlsruhe/Baden-Baden Airport (FKB) to Trapani Airport (TPS)plane plane FKB - TPS
    6h 56m
    €76–244

  3. Train, bus

    1. Take the train from Karlsruhe Hauptbahnhof to Heilbronn Hauptbahnhoftrain train
    2. Take the bus from Heilbronn ZOB - Fernbusbahnhof - Bahnhofstrasse 41 to Verona Porta Nuova Stationbus bus
    3. Take the train from Verona Porta Nuova to Roma Terminitrain train Fr
    4. Take the train from Roma Termini to Palermo Centraletrain train Ic
    25h 46m
    €243–445

  4. Drive, car ferry

    1. Drive from Karlsruhe to Port of Genoacar car
    2. Take the carferry from Port of Genoa to Port of Palermocarferry car ferry
    27h 32m
    €208–306

  5. Bus via Milan

    1. Take the bus from Karlsruhe central train station to Milano, Autostazione Lampugnanobus bus N77
    2. Take the bus from Milano, Autostazione Lampugnano to Palermobus bus N597
    32h 21m
    €180–274

  6. Train to Stuttgart Airport, fly to Palermo Airport

    1. Take the train from Karlsruhe Hbf to Stuttgart Hbftrain train
    2. Fly from Stuttgart Airport (STR) to Palermo Airport (PMO)plane plane STR - PMO
    6h 21m
    €94–327

  7. Train, train to Frankfurt, fly to Catania–Fontanarossa Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Mannheim, Hauptbahnhoftrain train
    2. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    3. Fly from Frankfurt (FRA) to Catania–Fontanarossa Airport (CTA)plane plane FRA - CTA
    6h 6m
    €96–294

  8. Train, train to Frankfurt, fly to Palermo Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Mannheim, Hauptbahnhoftrain train
    2. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    3. Fly from Frankfurt (FRA) to Palermo Airport (PMO)plane plane FRA - PMO
    6h 27m
    €95–285

  9. Train, train to Zurich Airport, fly to Palermo Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train
    2. Take the train from Basel SBB to Zürich HBtrain train
    3. Fly from Zurich Airport (ZRH) to Palermo Airport (PMO)plane plane ZRH - PMO
    8h 14m
    €129–343

  10. Train, train to Allgäu Airport, Memmingen, fly to Palermo Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Ulm Hauptbahnhoftrain train
    2. Take the train from Ulm Hauptbahnhof to Memmingen, Bahnhof ZOBtrain train
    3. Fly from Allgäu Airport, Memmingen (FMM) to Palermo Airport (PMO)plane plane FMM - PMO
    7h 57m
    €83–346

  11. Line 85569 train to Karlsruhe/Baden-Baden Airport, fly to Palermo Airport

    1. Take the train from Karlsruhe Marktplatz to Rastatttrain train
    2. Fly from Karlsruhe/Baden-Baden Airport (FKB) to Palermo Airport (PMO)plane plane FKB - PMO
    6h 14m

  12. Train, night train

    1. Take the train from Karlsruhe Hbf to Stuttgart Hbftrain train Ice / ...
    2. Take the nighttrain from Stuttgart Hbf to Verona Porta Nuovanighttrain night train Nj
    3. Take the train from Verona Porta Nuova to Roma Terminitrain train Fr
    4. Take the train from Roma Termini to Palermo Centraletrain train Ic
    31h 41m
    €214–470

  13. Bus

    1. Take the bus from Karlsruhe Central Bus Station to Palermo Piazza Cairolibus bus
    33h 25m
    €268–364

Karlsruhe to Sicily by bus

Calendar7Weekly Buses
Duration32h 21mAverage Duration
Ticket€180Cheapest Price
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Comparing Your Travel Options

Map of how to get from Karlsruhe to Sicily.ExpandLaunch map view
  • Distance: 1,435.6 km
  • Duration: 6h

What companies run services between Karlsruhe, Germany and Sicily, Italy?

You can take a bus from Karlsruhe central train station to Piazza Boiardo via Milano, Autostazione Lampugnano, Palermo, and Stazione Centrale Pensilina Esterna in around 32h 21m. Alternatively, Ryanair flies from Karlsruhe/Baden-Baden Airport (FKB) to Trapani Airport (TPS) 3 times a week.

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