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How to get fromKarlsruhe to Sicilyby train, plane, car, car ferry, night train, or bus

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There are 10 ways to get from Karlsruhe to Sicily by train, plane, car, car ferry, night train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Stuttgart Airport, fly to Catania–Fontanarossa Airport

    best
    1. Take the train from Karlsruhe Hbf to Stuttgart Hbftrain train
    2. Fly from Stuttgart Airport (STR) to Catania–Fontanarossa Airport (CTA)plane plane STR - CTA
    5h 51m
    €91–338

  2. Train, train to Allgäu Airport, Memmingen, fly to Catania–Fontanarossa Airport

    cheapest
    1. Take the train from Karlsruhe Hbf to Stuttgart Hbftrain train
    2. Take the train from Hauptbahnhof to Ulm Hauptbahnhoftrain train
    3. Take the train from Ulm Hauptbahnhof to Memmingen, Bahnhof ZOBtrain train
    4. Fly from Allgäu Airport, Memmingen (FMM) to Catania–Fontanarossa Airport (CTA)plane plane FMM - CTA
    7h 40m
    €70–430

  3. Drive, car ferry

    1. Drive from Karlsruhe to Port of Genoacar car
    2. Take the carferry from Port of Genoa to Port of Palermocarferry car ferry
    26h 17m
    €226–333

  4. Train, night train

    1. Take the train from Karlsruhe Hbf to Stuttgart Hbftrain train Ice / ...
    2. Take the nighttrain from Stuttgart Hbf to Venezia Mestrenighttrain night train Nj
    3. Take the train from Venezia Mestre to Roma Terminitrain train
    4. Take the train from Roma Termini to Palermo Centraletrain train Ic
    30h 51m
    €204–497

  5. Bus via Milan

    1. Take the bus from Karlsruhe central train station to Milano, Autostazione Lampugnanobus bus N77
    2. Take the bus from Milano, Autostazione Lampugnano to Palermobus bus N597
    32h 21m
    €195–289

  6. Train to Frankfurt, fly to Catania–Fontanarossa Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Catania–Fontanarossa Airport (CTA)plane plane FRA - CTA
    5h 56m
    €106–271

  7. Train to Frankfurt, fly to Palermo Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Palermo Airport (PMO)plane plane FRA - PMO
    6h 31m
    €105–272

  8. Train, train to Zurich Airport, fly to Palermo Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train
    2. Take the train from Basel SBB to Zürich HBtrain train
    3. Fly from Zurich Airport (ZRH) to Palermo Airport (PMO)plane plane ZRH - PMO
    8h 23m
    €136–435

  9. Train, car ferry

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train 12 / ...
    2. Take the train from Basel SBB to Zürich HBtrain train Tgv / ...
    3. Take the train from Zürich HB to Chiassotrain train Ec / ...
    4. Take the train from Chiasso to Genova P. Principetrain train Ec
    5. Take the carferry from Port of Genoa to Port of Palermocarferry car ferry
    31h 33m
    €277–593

  10. Bus

    1. Take the bus from Karlsruhe Central Bus Station to Palermo Piazza Cairolibus bus
    33h 35m
    €269–364

Karlsruhe to Sicily by train and night train

Calendar9Weekly Services
Duration30h 51mAverage Duration
Ticket€204Cheapest Price
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Comparing Your Travel Options

Map of how to get from Karlsruhe to Sicily.ExpandLaunch map view
  • Distance: 1,435.6 km
  • Duration: 5h 51m

What companies run services between Karlsruhe, Germany and Sicily, Italy?

You can take a bus from Karlsruhe central train station to Piazza Boiardo via Milano, Autostazione Lampugnano, Palermo, and Stazione Centrale Pensilina Esterna in around 32h 21m.

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