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How to get fromKarlsruhe to Syracuseby train, plane, bus, train (Trenitalia), night train, car, or car ferry

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There are 9 ways to get from Karlsruhe to Syracuse by train, plane, bus, train (Trenitalia), night train, car, or car ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Stuttgart Airport, fly, bus

    best
    1. Take the train from Karlsruhe Hbf to Stuttgart Hbftrain train
    2. Fly from Stuttgart Airport (STR) to Catania–Fontanarossa Airport (CTA)plane plane STR - CTA
    3. Take the bus from Catania Airport to Siracusa - v.le Scala Grecabus bus
    6h 55m
    €97–298

  2. Train to Basel, fly, bus

    cheapest
    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train
    2. Fly from Basel (BSL) to Catania–Fontanarossa Airport (CTA)plane plane BSL - CTA
    3. Take the bus from Catania Airport to Siracusa - v.le Scala Grecabus bus
    7h 37m
    €89–406

  3. Train

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train 12 / ...
    2. Take the train from Basel SBB to Luganotrain train Ec
    3. Take the train from Lugano to Milano Centraletrain train
    4. Take the train from Milano Centrale to Roma Terminitrain train
    5. Take the train from Roma Termini to Siracusatrain train Ic
    23h 12m
    €224–848

  4. Bus

    1. Take the bus from Karlsruhe Central Bus Station to Catania Central Bus Stationbus bus
    2. Take the bus from Catania Via Archimede to Siracusa - Von Platenbus bus Catania
    29h 36m

  5. Train, night train

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train 12 / ...
    2. Take the train from Basel SBB to Luganotrain train Ec
    3. Take the train from Lugano to Milano Centraletrain train
    4. Take the night train from Milano Centrale to Siracusanighttrain night train Ini
    29h 45m
    €199–778

  6. Train to Frankfurt, fly, bus

    1. Take the train from Karlsruhe Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Catania–Fontanarossa Airport (CTA)plane plane FRA - CTA
    3. Take the bus from Catania Airport to Siracusa - v.le Scala Grecabus bus
    6h 56m
    €113–322

  7. Train, train to Zurich Airport, fly, bus

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train
    2. Take the train from Basel SBB to Zürich HBtrain train
    3. Fly from Zurich Airport (ZRH) to Catania–Fontanarossa Airport (CTA)plane plane ZRH - CTA
    4. Take the bus from Catania Airport to Siracusa - v.le Scala Grecabus bus
    8h 42m
    €144–482

  8. Bus via Milan

    1. Take the bus from Karlsruhe central train station to Milanbus bus
    2. Take the bus from Milan Lampugnano to Catania Fontanarossa Airport Bus Stopbus bus
    3. Take the bus from Catania Airport to Siracusa - Von Platenbus bus
    29h 56m
    €135–265

  9. Drive, car ferry

    1. Drive from Karlsruhe to Villa S. Giovannicar car
    2. Take the car ferry from Villa S. Giovanni to Tresmestiericarferry car ferry
    3. Drive from Tresmestieri to Syracusecar car
    18h 40m
    €318–468

Karlsruhe to Syracuse by train and night train

Calendar7Weekly Services
Duration29h 45mAverage Duration
Ticket€199Cheapest Price
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Questions & Answers

Map of how to get from Karlsruhe to Syracuse.ExpandLaunch map view
  • Distance: 1,489.9 km
  • Duration: 6h 55m

What companies run services between Karlsruhe, Germany and Syracuse, Italy?

You can take a train from Karlsruhe Hauptbahnhof to Siracusa via Basel SBB, Lugano, Milano Centrale, and Roma Termini in around 23h 12m. Alternatively, you can take a bus from Karlsruhe Central Bus Station to Siracusa - Von Platen via Catania Central Bus Station and Catania Via Archimede in around 29h 36m.

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