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How to get fromKarlsruhe to Tuscanyby train (Trenitalia), bus, train, night train, car, or plane

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There are 10 ways to get from Karlsruhe to Tuscany by train (Trenitalia), bus, train, night train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train 12 / ...
    2. Take the train from Basel SBB to Luganotrain train Ec
    3. Take the train from Lugano to Milano Centraletrain train
    4. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    9h 56m
    €100–324

  2. Bus via Fortezza

    cheapest
    1. Take the bus from Karlsruhe central train station to Florence Villa Constanza Bus Stationbus bus N77
    14h 46m
    €78–114

  3. Bus

    1. Take the bus from Karlsruhe Central Bus Station to Florence Villa Constanza Bus Stationbus bus
    11h 38m
    €116–156

  4. Train, night train

    1. Take the train from Karlsruhe Hbf to Stuttgart Hbftrain train Ice / ...
    2. Take the nighttrain from Stuttgart Hbf to Verona Porta Nuovanighttrain night train Nj
    3. Take the train from Verona Porta Nuova to Firenze S.M.N.train train Fr
    16h 52m
    €82–208

  5. Drive  824.1 km

    1. Drive from Karlsruhe to Florencecar car 824.1 km
    8h 1m
    €131–190

  6. Train to Stuttgart Airport, fly to Florence Peretola Airport

    1. Take the train from Karlsruhe Hbf to Stuttgart Hbftrain train
    2. Fly from Stuttgart Airport (STR) to Florence Peretola Airport (FLR)plane plane STR - FLR
    6h 44m
    €113–313

  7. Train, train to Frankfurt, fly to Florence Peretola Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Mannheim, Hauptbahnhoftrain train
    2. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    3. Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane plane FRA - FLR
    5h 15m
    €136–329

  8. Train, train to Frankfurt, fly to Pisa International Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Mannheim, Hauptbahnhoftrain train
    2. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    3. Fly from Frankfurt (FRA) to Pisa International Airport (PSA)plane plane FRA - PSA
    4h 49m
    €114–297

  9. Train, train to Frankfurt, fly to Bologna Guglielmo Marconi Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Mannheim, Hauptbahnhoftrain train
    2. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    3. Fly from Frankfurt (FRA) to Bologna Guglielmo Marconi Airport (BLQ)plane plane FRA - BLQ
    4. Take the train from Bologna Centrale to Firenze S.M.N.train train
    5h 41m
    €123–319

  10. Train, train to Zurich Airport, fly to Florence Peretola Airport

    1. Take the train from Karlsruhe Hauptbahnhof to Basel SBBtrain train
    2. Take the train from Basel SBB to Zürich HBtrain train
    3. Fly from Zurich Airport (ZRH) to Florence Peretola Airport (FLR)plane plane ZRH - FLR
    6h 57m
    €156–400

Karlsruhe to Tuscany by train

Calendar76Weekly Trains
Duration9h 56mAverage Duration
Ticket€100Cheapest Price
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Questions & Answers

Map of how to get from Karlsruhe to Tuscany.ExpandLaunch map view
  • Distance: 826.4 km
  • Duration: 9h 56m

What companies run services between Karlsruhe, Germany and Tuscany, Italy?

You can take a train from Karlsruhe Hauptbahnhof to Firenze S.M.N. via Basel SBB, Lugano, and Milano Centrale in around 9h 56m. Alternatively, Onebus operates a bus from Karlsruhe Central Bus Station to Florence Villa Constanza Bus Station once a week. Tickets cost €110–160 and the journey takes 11h 17m.

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