There are 5 ways to get from Keene to Sanford by bus (Greyhound, Flixbus), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus via Boston
best- Take the bus from Keene to Springfield Union Stationbus
- Take the bus from Springfield Union Station to Bostonbus
- Take the bus from Boston to Wells Transportation Centerbus
7h 13m$76–150Drive 101.5 mi
cheapest- Drive from Keene to Sanfordcar 101.5 mi
2h 24m$19–27Bus, train via Fitchburg
- Take the bus from Keene to Greenfield John Olver Transit Ctrbus
- Take the bus from Greenfield John Olver Transit Ctr to Fitchburg MAbus
- Take the train from Fitchburg to North Stationtrain
- Take the train from Boston to Wellstrain
9h 1m$88–151Bus, train
- Take the bus from Keene to Greenfield John Olver Transit Ctrbus
- Take the bus from Greenfield John Olver Transit Ctr to Robert B Kennedy Bus Transfer Centerbus
- Take the train from Woburn Amtrak Station to Wellstrain
8h 23m$82–147Bus
- Take the bus from Keene to Springfield Union Stationbus Greyhound US0255s
- Take the bus from Springfield Union Station to Portsmouth Bus Stopbus FlixBus N2615
9h 32m$133–186
Questions & Answers
The cheapest way to get from Keene to Sanford is to drive which costs $18 - $27 and takes 2h 24m.
The fastest way to get from Keene to Sanford is to drive which takes 2h 24m and costs $18 - $27.
No, there is no direct bus from Keene to Sanford. However, there are services departing from Keene and arriving at Wells Transportation Center via Springfield Union Station and Boston. The journey, including transfers, takes approximately 7h 13m.
The distance between Keene and Sanford is 259 miles. The road distance is 102.1 miles.
The best way to get from Keene to Sanford without a car is to bus via Boston which takes 7h 13m and costs $75 - $150.
It takes approximately 7h 13m to get from Keene to Sanford, including transfers.
Keene to Sanford bus services, operated by Greyhound USA, depart from Keene station.
Keene to Sanford bus services, operated by Greyhound USA, arrive at Springfield Union Station.
Yes, the driving distance between Keene to Sanford is 102 miles. It takes approximately 2h 24m to drive from Keene to Sanford.
There are 193+ hotels available in Sanford.
What companies run services between Keene, NH, USA and Sanford, ME, USA?
You can take a bus from Keene to Sanford via Springfield Union Station, Boston, and Wells Transportation Center in around 7h 13m.
Train from Fitchburg to North Station
- Ave. Duration
- 1h 28m
- Frequency
- Every 2 hours
- Estimated price
- $9–15
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $9–15
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Boston to Wells
- Ave. Duration
- 1h 48m
- Frequency
- 5 times a day
- Estimated price
- $26–55
- Website
- Amtrak
Train from Woburn Amtrak Station to Wells
- Ave. Duration
- 1h 30m
- Frequency
- 5 times a day
- Estimated price
- $22–50
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Keene to Springfield Union Station
- Ave. Duration
- 2h 5m
- Frequency
- Twice daily
- Estimated price
- $11–22
- Website
- Greyhound
Bus from Springfield Union Station to Boston
- Ave. Duration
- 1h 40m
- Frequency
- Hourly
- Estimated price
- $13–26
- Website
- Greyhound
Bus from Boston to Wells Transportation Center
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $11–23
- Website
- Greyhound
Bus from Keene to Greenfield John Olver Transit Ctr
- Ave. Duration
- 1h
- Frequency
- Twice daily
- Estimated price
- $5–12
- Website
- Greyhound
Bus from Greenfield John Olver Transit Ctr to Fitchburg MA
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $7–15
- Website
- Greyhound
Bus from Keene to Greenfield John Olver Transit Ctr
- Ave. Duration
- 1h
- Frequency
- Twice daily
- Estimated price
- $5–12
- Website
- Greyhound
Bus from Greenfield John Olver Transit Ctr to Robert B Kennedy Bus Transfer Center
- Ave. Duration
- 2h 35m
- Frequency
- Once daily
- Estimated price
- $12–23
- Website
- Greyhound
Bus from Keene to Springfield Union Station
- Ave. Duration
- 2h 5m
- Frequency
- Twice daily
- Estimated price
- $11–22
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Springfield Union Station to Boston
- Ave. Duration
- 2h 10m
- Frequency
- Every 4 hours
- Estimated price
- $13–23
- Schedules at
- Flixbus USA
Bus from Springfield Union Station to Portsmouth Bus Stop
- Ave. Duration
- 3h 10m
- Frequency
- Twice daily
- Estimated price
- $22–40
- Schedules at
- Flixbus USA
- Phone
- 1-800-343-9999
- Website
- Peter Pan
Bus from Springfield Union Station to Boston
- Ave. Duration
- 2h
- Frequency
- 4 times a day
- Estimated price
- $18–50
- Website
- Peter Pan
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide


















