There are 3 ways to get from Kentucky to Cape Girardeau by bus (Greyhound), car, bus, train, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Louisville, KY to Evansville, INbus
- Take the bus from Evansville Bus Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Cape Girardeaubus
9h 49m$95–213Drive 255.4 mi
cheapest- Drive from Louisville to Cape Girardeaucar 255.4 mi
4h 48m$44–64Bus, train, taxi
- Take the bus from Louisville, KY to Indianapolis Union Stationbus
- Take the bus from Indianapolis Union Station to Champaign Intermodal Trans Ctrbus
- Take the train from Champaign-Urbana to Carbondaletrain
- Take the taxi from Carbondale to Cape Girardeautaxi
10h 19m$244–369
Comparing Your Travel Options
The cheapest way to get from Kentucky to Cape Girardeau is to drive which costs $40 - $65 and takes 4h 48m.
The fastest way to get from Kentucky to Cape Girardeau is to drive which takes 4h 48m and costs $40 - $65.
No, there is no direct bus from Kentucky to Cape Girardeau. However, there are services departing from Louisville, KY and arriving at Cape Girardeau via Evansville Bus Station and St Louis Bus Station. The journey, including transfers, takes approximately 9h 49m.
The distance between Kentucky and Cape Girardeau is 405 miles. The road distance is 256.9 miles.
The best way to get from Kentucky to Cape Girardeau without a car is to bus which takes 9h 49m and costs $95 - $220.
It takes approximately 9h 49m to get from Kentucky to Cape Girardeau, including transfers.
Kentucky to Cape Girardeau bus services, operated by Miller Transportation, depart from Louisville, KY station.
Kentucky to Cape Girardeau bus services, operated by Miller Transportation, arrive at Evansville, IN station.
Cape Girardeau is 1h behind Kentucky. It is currently 10:49 PM in Kentucky and 9:49 PM in Cape Girardeau.
Yes, the driving distance between Kentucky to Cape Girardeau is 257 miles. It takes approximately 4h 48m to drive from Kentucky to Cape Girardeau.
What companies run services between Kentucky, USA and Cape Girardeau, MO, USA?
You can take a bus from Louisville, KY to Cape Girardeau via Evansville Bus Station, St Louis Bus Station, and Cape Girardeau in around 9h 49m.
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Champaign-Urbana to Carbondale
- Ave. Duration
- 2h 54m
- Frequency
- 3 times a day
- Estimated price
- $100–160
- Website
- Amtrak
- Phone
- +1 502-368-5644 x 135
- Website
- Miller Transportation
Bus from Louisville, KY to Evansville, IN
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $35–130
- Website
- Miller Transportation
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Evansville Bus Station to St Louis Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- Twice daily
- Estimated price
- $30–45
- Website
- Greyhound
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $20–35
- Website
- Greyhound
Bus from Indianapolis Union Station to Champaign Intermodal Trans Ctr
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $21–35
- Website
- Greyhound
Rome2Rio's guide to Amtrak Thruway
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Louisville, KY to Indianapolis Union Station
- Ave. Duration
- 2h 20m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Amtrak
- Adult
- $22–45
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Booking & Getting There
There are 23+ hotels available in Cape Girardeau.









