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How to get fromKentucky to Des Moinesby plane, bus (Greyhound, Amtrak), bus, train, car, taxi, or bus (Greyhound)

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There are 8 ways to get from Kentucky to Des Moines by plane, bus (Greyhound, Amtrak), bus, train, car, taxi, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Blue Grass Airport

    best
    1. Fly from Blue Grass Airport (LEX) to Des Moines (DSM)plane plane LEX - DSM
    4h 42m
    $158–708

  2. Bus

    cheapest
    1. Take the bus from Louisville Bus Station to Indianapolis Union Stationbus bus Greyhound US0100 / ...
    2. Take the bus from Indianapolis Union Station to Des Moinesbus bus Greyhound US0157S
    12h 50m
    $93–194

  3. Bus, train

    1. Take the bus from Louisville Bus Station to Indianapolis Union Stationbus bus
    2. Take the train from Indianapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    4. Take the bus from Galesburg to Des Moinesbus bus
    17h 26m
    $143–329

  4. Drive  580.9 mi

    1. Drive from Louisville to Des Moinescar car 580.9 mi
    9h 46m
    $106–154

  5. Fly from Louisville International Airport

    1. Fly from Louisville International Airport (SDF) to Des Moines (DSM)plane plane SDF - DSM
    5h 20m
    $159–874

  6. Fly from Covington

    1. Fly from Covington (CVG) to Des Moines (DSM)plane plane CVG - DSM
    5h 20m
    $158–872

  7. Taxi to Evansville, fly

    1. Take the taxi from Owensboro to Evansville (EVV)taxi taxi
    2. Fly from Evansville (EVV) to Des Moines (DSM)plane plane EVV - DSM
    6h 20m
    $220–781

  8. Bus via Speedway

    1. Take the bus from El Mercadito Grocery - Clarksville, IN to Indianapolisbus bus Memphis
    2. Take the bus from Indianapolis Union Station to Des Moinesbus bus Greyhound US0157S
    15h 35m
    $98–200

Kentucky to Des Moines by bus

Calendar7Weekly Buses
Duration12h 50mAverage Duration
Ticket$93Cheapest Price
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Questions & Answers

Map of how to get from Kentucky to Des Moines.ExpandLaunch map view
  • Distance: 553.2 mi
  • Duration: 4h 42m

What companies run services between Kentucky, USA and Des Moines, IA, USA?

United Airlines, Delta, and American Airlines fly from Blue Grass Airport (LEX) to Des Moines (DSM) hourly. Alternatively, you can take a bus from Louisville Bus Station to Des Moines via Indianapolis Union Station in around 12h 50m.

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