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How to get fromKentucky to La Crosseby plane, bus (Amtrak, Greyhound), bus, train, or car

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There are 7 ways to get from Kentucky to La Crosse by plane, bus (Amtrak, Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Blue Grass Airport

    best
    1. Fly from Blue Grass Airport (LEX) to La Crosse (LSE)plane plane LEX - LSE
    4h 34m
    $110–430

  2. Fly from Louisville International Airport

    cheapest
    1. Fly from Louisville International Airport (SDF) to La Crosse (LSE)plane plane SDF - LSE
    7h 20m
    $101–506

  3. Bus

    1. Take the bus from Louisville, KY to Chicago Union Stationbus bus
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to La Crossebus bus
    13h 37m
    $108–185

  4. Bus, train via Indianapolis

    1. Take the bus from Louisville Bus Station to Indianapolis Union Stationbus bus
    2. Take the train from Indianapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain train
    13h 54m
    $148–384

  5. Drive  575.8 mi

    1. Drive from Louisville to La Crossecar car 575.8 mi
    9h 43m
    $106–152

  6. Fly from Covington

    1. Fly from Covington (CVG) to La Crosse (LSE)plane plane CVG - LSE
    5h 48m
    $106–574

  7. Bus, train

    1. Take the bus from Louisville Bus Station to Bloomingtonbus bus
    2. Take the bus from Bloomington to Chicago Bus Stationbus bus
    3. Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain train
    14h 8m
    $124–276

Kentucky to La Crosse by bus

Calendar7Weekly Buses
Duration13h 37mAverage Duration
Ticket$108Cheapest Price
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Comparing Your Travel Options

Map of how to get from Kentucky to La Crosse.ExpandLaunch map view
  • Distance: 548.9 mi
  • Duration: 4h 34m

What companies run services between Kentucky, USA and La Crosse, WI, USA?

American Airlines and United Airlines fly from Blue Grass Airport (LEX) to La Crosse (LSE) every 4 hours. Alternatively, you can take a bus from Louisville, KY to La Crosse via Chicago Union Station, W Jackson Blvd, after S Clinton St, 250 N. Lake St - Madison UW Campus, and Madison in around 13h 37m.

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