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How to get fromKentucky to Panama Cityby plane, car, or bus

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There are 6 ways to get from Kentucky to Panama City by plane, car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Louisville International Airport to Northwest Florida Beaches International Airport

    best
    1. Fly from Louisville International Airport (SDF) to Northwest Florida Beaches International Airport (ECP)plane plane SDF - ECP
    5h 23m
    $147–533

  2. Fly Louisville International Airport to Destin–Fort Walton Beach Airport, drive

    cheapest
    1. Fly from Louisville International Airport (SDF) to Destin–Fort Walton Beach Airport (VPS)plane plane SDF - VPS
    2. Drive from Destin–Fort Walton Beach Airport (VPS) to Panama Citycar car
    4h 51m
    $89–471

  3. Drive 626.1 mi

    1. Drive from Louisville to Panama Citycar car 626.1 mi
    11h 2m
    $115–165

  4. Fly Blue Grass Airport to Destin–Fort Walton Beach Airport, drive

    1. Fly from Blue Grass Airport (LEX) to Destin–Fort Walton Beach Airport (VPS)plane plane LEX - VPS
    2. Drive from Destin–Fort Walton Beach Airport (VPS) to Panama Citycar car
    5h 25m
    $138–655

  5. Fly Covington to Destin–Fort Walton Beach Airport, drive

    1. Fly from Covington (CVG) to Destin–Fort Walton Beach Airport (VPS)plane plane CVG - VPS
    2. Drive from Destin–Fort Walton Beach Airport (VPS) to Panama Citycar car
    5h 1m
    $104–520

  6. Bus to Nashville, fly to Northwest Florida Beaches International Airport

    1. Take the bus from Louisville, KY to Nashvillebus bus
    2. Fly from Nashville (BNA) to Northwest Florida Beaches International Airport (ECP)plane plane BNA - ECP
    6h 33m
    $160–518

Louisville International Airport (SDF) to Northwest Florida Beaches International Airport (ECP) flights

Calendar73Weekly Planes
Duration4h 51mAverage Duration
Ticket$80Cheapest Price
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Questions & Answers

Map of how to get from Kentucky to Panama City.ExpandLaunch map view
  • Distance: 571.5 mi
  • Duration: 5h 23m

What companies run services between Kentucky, USA and Panama City, FL, USA?

Southwest Airlines, Delta, and American Airlines fly from Louisville International Airport (SDF) to Northwest Florida Beaches International Airport (ECP) every 3 hours.

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