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How to get fromKentucky to Sioux Fallsby plane, bus (Amtrak, Greyhound), bus, train, car, taxi, or bus (Amtrak, Flixbus)

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There are 9 ways to get from Kentucky to Sioux Falls by plane, bus (Amtrak, Greyhound), bus, train, car, taxi, or bus (Amtrak, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Blue Grass Airport

    best
    1. Fly from Blue Grass Airport (LEX) to Sioux Falls (FSD)plane plane LEX - FSD
    6h 31m
    $108–449

  2. Fly from Owensboro–Daviess County Regional Airport

    cheapest
    1. Fly from Owensboro–Daviess County Regional Airport (OWB) to Sioux Falls (FSD)plane plane OWB - FSD
    10h 3m
    $88–425

  3. Bus

    1. Take the bus from Louisville, KY to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Des Moinesbus bus
    3. Take the bus from Des Moines to Omaha, NEbus bus
    4. Take the bus from Omaha to Sioux Fallsbus bus
    22h 53m
    $172–276

  4. Bus, train

    1. Take the bus from Louisville, KY to Indianapolis Union Stationbus bus
    2. Take the train from Indianapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    4. Take the bus from Minneapolis to Sioux Fallsbus bus
    24h 28m
    $423–683

  5. Drive  825 mi

    1. Drive from Louisville to Sioux Fallscar car 825 mi
    15h 3m
    $151–218

  6. Fly from Covington

    1. Fly from Covington (CVG) to Sioux Falls (FSD)plane plane CVG - FSD
    6h 55m
    $104–604

  7. Fly from Louisville International Airport

    1. Fly from Louisville International Airport (SDF) to Sioux Falls (FSD)plane plane SDF - FSD
    7h 12m
    $104–555

  8. Taxi to Evansville, fly

    1. Take the taxi from Owensboro to Evansville (EVV)taxi taxi
    2. Fly from Evansville (EVV) to Sioux Falls (FSD)plane plane EVV - FSD
    7h 29m
    $170–512

  9. Bus via Milwaukee Airport (MKE)

    1. Take the bus from Louisville, KY to Chicago Union Stationbus bus
    2. Take the bus from Chicago Bus Station to Milwaukee Mitchell Airportbus bus
    3. Take the bus from Milwaukee Mitchell Airport to Minneapolis Bus Stationbus bus
    4. Take the bus from Minneapolis to Sioux Fallsbus bus
    25h 22m
    $179–263

Blue Grass Airport (LEX) to Sioux Falls (FSD) flights

Calendar87Weekly Planes
Duration6h 45mAverage Duration
Ticket$78Cheapest Price
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Comparing Your Travel Options

Map of how to get from Kentucky to Sioux Falls.ExpandLaunch map view
  • Distance: 755.2 mi
  • Duration: 6h 31m

What companies run services between Kentucky, USA and Sioux Falls, SD, USA?

United Airlines, Delta, and two other airlines fly from Blue Grass Airport (LEX) to Sioux Falls (FSD) every 2 hours. Alternatively, you can take a bus from Louisville, KY to The Bus Stop via Indianapolis Union Station, Des Moines, Omaha, Sioux Falls, and Maple/Career NE corner in around 22h 53m.

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