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How to get fromKentucky to Sioux Fallsby plane, bus (Amtrak, Greyhound), bus, train, car, taxi, or bus (Amtrak, Flixbus)

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There are 8 ways to get from Kentucky to Sioux Falls by plane, bus (Amtrak, Greyhound), bus, train, car, taxi, or bus (Amtrak, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Blue Grass Airport

    best
    1. Fly from Blue Grass Airport (LEX) to Sioux Falls (FSD)plane plane LEX - FSD
    6h 1m
    $153–639

  2. Fly from Louisville International Airport

    cheapest
    1. Fly from Louisville International Airport (SDF) to Sioux Falls (FSD)plane plane SDF - FSD
    7h 5m
    $99–485

  3. Bus via Des Moines

    1. Take the bus from Louisville, KY to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Des Moinesbus bus
    3. Take the bus from Des Moines to Omaha, NEbus bus
    4. Take the bus from Omaha to Sioux Fallsbus bus
    23h 3m
    $172–316

  4. Bus, train

    1. Take the bus from Louisville, KY to Indianapolis Union Stationbus bus
    2. Take the train from Indianapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    4. Take the bus from Burnsville to Sioux Fallsbus bus
    24h 45m
    $295–563

  5. Drive 846.5 mi

    1. Drive from Louisville to Sioux Fallscar car 846.5 mi
    14h 12m
    $155–224

  6. Fly from Covington

    1. Fly from Covington (CVG) to Sioux Falls (FSD)plane plane CVG - FSD
    6h 55m
    $104–554

  7. Taxi to Evansville, fly

    1. Take the taxi from Owensboro to Evansville (EVV)taxi taxi
    2. Fly from Evansville (EVV) to Sioux Falls (FSD)plane plane EVV - FSD
    7h 31m
    $170–502

  8. Bus

    1. Take the bus from Louisville, KY to Chicago Union Stationbus bus
    2. Take the bus from Chicago Bus Station to Saint Cloudbus bus
    3. Take the bus from St. Cloud to Sioux Fallsbus bus
    26h 2m
    $192–289

Blue Grass Airport (LEX) to Sioux Falls (FSD) flights

Calendar79Weekly Planes
Duration6h 18mAverage Duration
Ticket$120Cheapest Price
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Questions & Answers

Map of how to get from Kentucky to Sioux Falls.ExpandLaunch map view
  • Distance: 755.2 mi
  • Duration: 6h 1m

What companies run services between Kentucky, USA and Sioux Falls, SD, USA?

United Airlines, Delta, and two other airlines fly from Blue Grass Airport (LEX) to Sioux Falls (FSD) every 2 hours. Alternatively, you can take a bus from Louisville, KY to The Bus Stop via Indianapolis Union Station, Des Moines, Omaha, Sioux Falls, and Maple/Career NE corner in around 23h 3m.

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