There are 7 ways to get from Kentucky to Sioux Falls by plane, bus (Amtrak, Greyhound), bus, train, car, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Blue Grass Airport
best- Fly from Blue Grass Airport (LEX) to Sioux Falls (FSD)plane LEX - FSD
6h 4m$113–459Fly from Louisville International Airport
cheapest- Fly from Louisville International Airport (SDF) to Sioux Falls (FSD)plane SDF - FSD
7h 6m$99–505Bus
- Take the bus from Louisville, KY to Indianapolis Union Stationbus
- Take the bus from Indianapolis Union Station to Des Moinesbus
- Take the bus from Des Moines to Omaha, NEbus
- Take the bus from Omaha to Sioux Fallsbus
22h 58m$159–291Bus, train
- Take the bus from Louisville, KY to Indianapolis Union Stationbus
- Take the train from Indianapolis to Chicago Union Stationtrain
- Take the train from Chicago Union Station to St. Paul-Minneapolistrain
- Take the bus from Minneapolis to Fairmontbus
- Take the bus from Fairmont to Sioux Fallsbus
25h 6m$273–554Drive 846.5 mi
- Drive from Louisville to Sioux Fallscar 846.5 mi
14h 12m$155–224Fly from Covington
- Fly from Covington (CVG) to Sioux Falls (FSD)plane CVG - FSD
7h 5m$104–554Taxi to Evansville, fly
- Take the taxi from Owensboro to Evansville (EVV)taxi
- Fly from Evansville (EVV) to Sioux Falls (FSD)plane EVV - FSD
8h 19m$170–512
Blue Grass Airport (LEX) to Sioux Falls (FSD) flights
Questions & Answers
The cheapest way to get from Kentucky to Sioux Falls is to drive which costs $150 - $230 and takes 14h 12m.
The fastest way to get from Kentucky to Sioux Falls is to fly which takes 6h 4m and costs $110 - $460.
No, there is no direct bus from Kentucky to Sioux Falls. However, there are services departing from Louisville, KY and arriving at The Bus Stop via Indianapolis Union Station, Des Moines, Omaha and Maple/Career NE corner. The journey, including transfers, takes approximately 22h 58m.
The distance between Kentucky and Sioux Falls is 760 miles. The road distance is 851.5 miles.
The best way to get from Kentucky to Sioux Falls without a car is to bus which takes 22h 58m and costs $150 - $300.
It takes approximately 6h 4m to get from Kentucky to Sioux Falls, including transfers.
Kentucky to Sioux Falls bus services, operated by Amtrak Thruway, depart from Louisville, KY station.
The best way to get from Kentucky to Sioux Falls is to fly which takes 6h 4m and costs $110 - $460. Alternatively, you can bus, which costs $150 - $300 and takes 22h 58m.
Kentucky to Sioux Falls bus services, operated by Amtrak Thruway, arrive at Indianapolis Union Station.
Sioux Falls is 1h behind Kentucky. It is currently 4:21 AM in Kentucky and 3:21 AM in Sioux Falls.
What companies run services between Kentucky, USA and Sioux Falls, SD, USA?
United Airlines, Delta, and two other airlines fly from Blue Grass Airport (LEX) to Sioux Falls (FSD) every 2 hours. Alternatively, you can take a bus from Louisville, KY to The Bus Stop via Indianapolis Union Station, Des Moines, Omaha, Sioux Falls, and Maple/Career NE corner in around 22h 58m.
- Website
- aa.com
Flights from Blue Grass Airport to Sioux Falls via Dallas/Ft.Worth
- Ave. Duration
- 7h 11m
- When
- Every day
- Estimated price
- $130–600
Flights from Blue Grass Airport to Sioux Falls via Chicago O'Hare
- Ave. Duration
- 7h 31m
- When
- Every day
- Estimated price
- $80–420
Flights from Louisville International Airport to Sioux Falls via Chicago O'Hare
- Ave. Duration
- 5h 49m
- When
- Every day
- Estimated price
- $95–500
Flights from Louisville International Airport to Sioux Falls via Dallas/Ft.Worth
- Ave. Duration
- 7h 3m
- When
- Every day
- Estimated price
- $150–700
Flights from Covington to Sioux Falls via Chicago O'Hare
- Ave. Duration
- 5h 26m
- When
- Every day
- Estimated price
- $100–550
Flights from Covington to Sioux Falls via Dallas/Ft.Worth
- Ave. Duration
- 6h 27m
- When
- Every day
- Estimated price
- $170–800
Flights from Evansville to Sioux Falls via Dallas/Ft.Worth
- Ave. Duration
- 8h 17m
- When
- Every day
- Estimated price
- $120–550
Flights from Evansville to Sioux Falls via Chicago O'Hare
- Ave. Duration
- 8h 25m
- When
- Every day
- Estimated price
- $75–400
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Indianapolis to Chicago Union Station
- Ave. Duration
- 5h
- Frequency
- 3 times a week
- Estimated price
- $50–120
- Website
- Amtrak
Train from Chicago Union Station to St. Paul-Minneapolis
- Ave. Duration
- 7h 31m
- Frequency
- 3 times a day
- Estimated price
- $110–250
- Website
- Amtrak
Rome2Rio's guide to Amtrak Thruway
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Louisville, KY to Indianapolis Union Station
- Ave. Duration
- 2h 20m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Amtrak
- Adult
- $22–45
Bus from Louisville, KY to Indianapolis Union Station
- Ave. Duration
- 2h 20m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Amtrak
- Adult
- $22–45
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More Questions & Answers
Yes, the driving distance between Kentucky to Sioux Falls is 851 miles. It takes approximately 14h 12m to drive from Kentucky to Sioux Falls.
There are 80+ hotels available in Sioux Falls.




