Rome2Rio

How to get fromKentucky to Winston-Salemby plane, bus, bus (Amtrak, Greyhound, Flixbus), train, car, or bus (Amtrak, Greyhound)

Find Transport to Winston-Salem

See all options

There are 8 ways to get from Kentucky to Winston-Salem by plane, bus, bus (Amtrak, Greyhound, Flixbus), train, car, or bus (Amtrak, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Blue Grass Airport, bus

    best
    1. Fly from Blue Grass Airport (LEX) to Charlotte Douglas International Airport (CLT)plane plane LEX - CLT
    2. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    4h 56m
    $118–533

  2. Drive  420.1 mi

    cheapest
    1. Drive from Louisville to Winston-Salemcar car 420.1 mi
    8h 10m
    $77–111

  3. Bus via Atlanta

    1. Take the bus from Louisville, KY to Nashvillebus bus
    2. Take the bus from Nashville Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Winston Salem(Trans Center)bus bus
    15h 45m
    $123–196

  4. Bus, train

    1. Take the bus from Louisville, KY to Indianapolis Union Stationbus bus
    2. Take the train from Indianapolis to Charlottesvilletrain train
    3. Take the train from Charlottesville to Greensborotrain train
    4. Take the bus from Greensboro Bus Stop to Winston Salem(Trans Center)bus bus
    24h 48m
    $452–751

  5. Fly from Tri-State Airport, bus

    1. Fly from Tri-State Airport (HTS) to Charlotte Douglas International Airport (CLT)plane plane HTS - CLT
    2. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    4h 52m
    $109–518

  6. Fly from Louisville International Airport, bus

    1. Fly from Louisville International Airport (SDF) to Charlotte Douglas International Airport (CLT)plane plane SDF - CLT
    2. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    6h 12m
    $109–629

  7. Fly from Covington, bus

    1. Fly from Covington (CVG) to Charlotte Douglas International Airport (CLT)plane plane CVG - CLT
    2. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    6h 22m
    $128–778

  8. Bus

    1. Take the bus from Louisville, KY to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Wilson & Ferrell Shell Station - Columbusbus bus
    3. Take the bus from Columbus to Charlestonbus bus
    4. Take the bus from Charleston Bus Station to Winston Salem(Trans Center)bus bus
    19h 25m
    $113–214

Kentucky to Winston-Salem by bus

Calendar14Weekly Buses
Duration15h 45mAverage Duration
Ticket$123Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Kentucky to Winston-Salem.ExpandLaunch map view
  • Distance: 375.1 mi
  • Duration: 4h 56m

What companies run services between Kentucky, USA and Winston-Salem, NC, USA?

You can take a bus from Louisville, KY to Winston Salem(Trans Center) via Nashville Bus Station and Atlanta Bus Station in around 15h 45m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There