There are 6 ways to get from Kentucky to Winston-Salem by plane, bus, bus (Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Blue Grass Airport, bus
best- Fly from Blue Grass Airport (LEX) to Charlotte Douglas International Airport (CLT)plane LEX - CLT
- Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus
5h 1m$107–523Drive 420.1 mi
cheapest- Drive from Louisville to Winston-Salemcar 420.1 mi
8h 8m$77–111Bus
- Take the bus from Louisville to Columbusbus Bsb 28 / ...
- Take the bus from Columbus to Winston Salem(Trans Center)bus Greyhound US0140
14h 35m$99–163Fly from Tri-State Airport, bus
- Fly from Tri-State Airport (HTS) to Charlotte Douglas International Airport (CLT)plane HTS - CLT
- Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus
4h 58m$98–508Fly from Louisville International Airport, bus
- Fly from Louisville International Airport (SDF) to Charlotte Douglas International Airport (CLT)plane SDF - CLT
- Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus
6h 16m$103–649Fly from Covington, bus
- Fly from Covington (CVG) to Charlotte Douglas International Airport (CLT)plane CVG - CLT
- Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus
6h 22m$112–698
Kentucky to Winston-Salem by bus
Comparing Your Travel Options
The cheapest way to get from Kentucky to Winston-Salem is to drive which costs $75 - $120 and takes 8h 8m.
The fastest way to get from Kentucky to Winston-Salem is to fly and bus which takes 4h 58m and costs $95 - $550.
No, there is no direct bus from Kentucky to Winston-Salem. However, there are services departing from Louisville and arriving at Winston Salem(Trans Center) via Columbus. The journey, including transfers, takes approximately 14h 35m.
The distance between Kentucky and Winston-Salem is 377 miles. The road distance is 422.6 miles.
The best way to get from Kentucky to Winston-Salem without a car is to bus which takes 14h 35m and costs $95 - $170.
It takes approximately 5h 1m to get from Kentucky to Winston-Salem, including transfers.
Kentucky to Winston-Salem bus services, operated by Barons Bus, depart from Louisville station.
Kentucky to Winston-Salem bus services, operated by Barons Bus, arrive at Columbus station.
Yes, the driving distance between Kentucky to Winston-Salem is 423 miles. It takes approximately 8h 8m to drive from Kentucky to Winston-Salem.
Book your Kentucky to Winston-Salem bus tickets online with Omio and FlixBus.
What companies run services between Kentucky, USA and Winston-Salem, NC, USA?
You can take a bus from Louisville to Winston Salem(Trans Center) via Columbus in around 14h 35m.
- Website
- aa.com
Flights from Blue Grass Airport to Charlotte Douglas International Airport
- Ave. Duration
- 1h 38m
- When
- Every day
- Estimated price
- $65–440
Flights from Tri-State Airport to Charlotte Douglas International Airport
- Ave. Duration
- 1h 26m
- When
- Every day
- Estimated price
- $60–430
Flights from Louisville International Airport to Charlotte Douglas International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $90–600
Flights from Covington to Charlotte Douglas International Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $100–650
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- $12–19
- Website
- Greyhound
Bus from Louisville to Columbus
- Ave. Duration
- 5h 25m
- Frequency
- Once daily
- Estimated price
- $30–55
- Website
- Greyhound
Bus from Columbus to Winston Salem(Trans Center)
- Ave. Duration
- 9h 20m
- Frequency
- Once daily
- Estimated price
- $65–110
- Website
- Greyhound
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- $12–19
- Website
- Greyhound
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- $12–19
- Website
- Greyhound
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- $12–19
- Website
- Greyhound
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Booking & Getting There
There are 145+ hotels available in Winston-Salem.


