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How to get fromKeokuk to Sioux Fallsby car, plane, train, or bus

Find Transport to Sioux Falls

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There are 4 ways to get from Keokuk to Sioux Falls by car, plane, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive, fly

    best
    1. Drive from Keokuk to Cedar-Rapids-Airport-CIDcar car
    2. Fly from The Eastern Iowa Airport (CID) to Sioux Falls (FSD)plane plane CID - FSD
    7h 2m
    $78–382

  2. Train, bus via Kansas City

    1. Take the train from Fort Madison to Kansas Citytrain train Southwest Chief
    2. Take the bus from Kansas City to Sioux Fallsbus bus Jefferson Lines 705
    14h 40m
    $291–422

  3. Drive  445.4 mi

    1. Drive from Keokuk to Sioux Fallscar car 445.4 mi
    8h 15m
    $82–118

  4. Train, bus

    1. Take the train from Fort Madison to Galesburg Amtrak Stationtrain train
    2. Take the bus from Galesburg to Des Moinesbus bus
    3. Take the bus from Des Moines to Omaha, NEbus bus
    4. Take the bus from Omaha to Sioux Fallsbus bus
    17h 9m
    $204–297

The Eastern Iowa Airport (CID) to Sioux Falls (FSD) flights

Calendar97Weekly Planes
Duration5h 47mAverage Duration
Ticket$56Cheapest Price
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Comparing Your Travel Options

Map of how to get from Keokuk to Sioux Falls.ExpandLaunch map view
  • Distance: 400 mi
  • Duration: 7h 2m

What companies run services between Keokuk, IA, USA and Sioux Falls, SD, USA?

There is no direct connection from Keokuk to Sioux Falls. However, you can drive to Cedar-Rapids-Airport-CID airport, fly to Sioux Falls (FSD), walk to 4th Ave/Wells Fargo crosswalk, then take the line 8 bus to Cliff/3rd NW corner. Alternatively, you can take a vehicle from Keokuk to Sioux Falls via Fort Madison, Kansas City, On Grand At Pershing Farside Northbound, On 12Th At Charlotte Eastbound Nearside, Kansas City, and Sioux Falls in around 14h 40m.

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