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How to get fromKey Largo to Charlestonby shuttle, plane, bus, train, or car

Find Transport to Charleston

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There are 4 ways to get from Key Largo to Charleston by shuttle, plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Shuttle to Miami International Airport, fly

    best
    1. Take a shuttle bus from Key Largo, FL to Miami, FL - International Airportshuttle bus
    2. Fly from Miami International Airport (MIA) to Charleston International Airport (CHS)plane plane MIA - CHS
    5h 37m
    $602–1,128

  2. Drive  643.4 mi

    cheapest
    1. Drive from Key Largo to Charlestoncar car 643.4 mi
    10h 59m
    $118–170

  3. Bus, train

    1. Take the bus from Key Largo Bus Stop to Miami Airport Stationbus bus Greyhound US0720s
    2. Take the train from Hollywood Amtrak Station to Charleston Amtrak Stationtrain train Silver Meteor
    16h 33m
    $212–440

  4. Shuttle to Fort Lauderdale–Hollywood International Airport, fly

    1. Take a shuttle bus from Key Largo, FL to Fort Lauderdale, FL - International Airportshuttle bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Charleston International Airport (CHS)plane plane FLL - CHS
    5h 59m
    $529–1,247

Miami International Airport (MIA) to Charleston International Airport (CHS) flights

Calendar55Weekly Planes
Duration3h 48mAverage Duration
Ticket$68Cheapest Price
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Questions & Answers

Map of how to get from Key Largo to Charleston.ExpandLaunch map view
  • Distance: 562.7 mi
  • Duration: 5h 37m

What companies run services between Key Largo, FL, USA and Charleston, SC, USA?

There is no direct connection from Key Largo to Charleston. However, you can take the shuttle to Miami, FL - International Airport, walk to Miami International Airport (MIA) airport, fly to Charleston International Airport (CHS), walk to Charleston International Airport, then take the line 11 bus to Transit Mall. Alternatively, you can take a bus from Key Largo Bus Stop to Charleston via Miami, Airport Intermodal Station, Miami Airport Station, Hollywood Station, Hollywood Amtrak Station, and Charleston Amtrak Station in around 16h 33m.

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