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How to get fromKey Largo to Columbiaby shuttle, plane, car, bus, train, or bus (Greyhound, Flixbus)

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There are 6 ways to get from Key Largo to Columbia by shuttle, plane, car, bus, train, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Shuttle to Miami International Airport, fly to Charleston International Airport, drive

    best
    1. Take a shuttle bus from Key Largo, FL to Miami, FL - International Airportshuttle bus
    2. Fly from Miami International Airport (MIA) to Charleston International Airport (CHS)plane plane MIA - CHS
    3. Drive from Charleston-Airport-CHS to Columbiacar car
    5h 47m
    $619–1,155

  2. Bus

    cheapest
    1. Take the bus from Key Largo Bus Stop to Miami Airport Stationbus bus
    2. Take the bus from Miami Airport Station to Jacksonvillebus bus
    3. Take the bus from Jacksonville to Sumter Bus Stopbus bus
    4. Take the bus from James E Clyburn Intermodal Transportation Center to Assembly Senate Northbus bus 44
    21h 4m
    $127–212

  3. Bus, train

    1. Take the bus from Key Largo Bus Stop to Miami Airport Stationbus bus Greyhound US0720s
    2. Take the train from Hollywood Amtrak Station to Columbia Stationtrain train Floridian
    20h 5m
    $433–671

  4. Drive  693.7 mi

    1. Drive from Key Largo to Columbiacar car 693.7 mi
    11h 32m
    $127–183

  5. Shuttle to Fort Lauderdale–Hollywood International Airport, fly to Charleston International Airport, drive

    1. Take a shuttle bus from Key Largo, FL to Fort Lauderdale, FL - International Airportshuttle bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Charleston International Airport (CHS)plane plane FLL - CHS
    3. Drive from Charleston-Airport-CHS to Columbiacar car
    6h 18m
    $546–1,274

  6. Shuttle to Miami International Airport, fly to Savannah, train

    1. Take a shuttle bus from Key Largo, FL to Miami, FL - International Airportshuttle bus
    2. Fly from Miami International Airport (MIA) to Savannah (SAV)plane plane MIA - SAV
    3. Take the train from Savannah Station to Columbia Stationtrain train
    7h 31m
    $310–846

Key Largo to Columbia by bus and train

Calendar7Weekly Services
Duration20h 5mAverage Duration
Ticket$433Cheapest Price
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Comparing Your Travel Options

Map of how to get from Key Largo to Columbia.ExpandLaunch map view
  • Distance: 655.9 mi
  • Duration: 5h 47m

What companies run services between Key Largo, FL, USA and Columbia, SC, USA?

You can take a bus from Key Largo Bus Stop to Assembly Senate North via Miami Airport Station, Jacksonville, Sumter Bus Stop, and James E Clyburn Intermodal Transportation Center in around 21h 4m.

Airlines
Train operators
Bus operators

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