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How to get fromKey Largo to Columbiaby shuttle, plane, train, bus, or car

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There are 5 ways to get from Key Largo to Columbia by shuttle, plane, train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Shuttle to Miami International Airport, fly to Savannah, train

    best
    1. Take a shuttle bus from Key Largo, FL to Miami, FL - International Airportshuttle bus
    2. Fly from Miami International Airport (MIA) to Savannah (SAV)plane plane MIA - SAV
    3. Take the train from Savannah Station to Columbia Stationtrain train
    7h 31m
    $265–756

  2. Drive  693.7 mi

    cheapest
    1. Drive from Key Largo to Columbiacar car 693.7 mi
    11h 32m
    $127–183

  3. Bus, train

    1. Take the bus from Key Largo Bus Stop to Miami Airport Stationbus bus Greyhound US0720s
    2. Take the train from Hollywood Amtrak Station to Columbia Stationtrain train Floridian
    20h 5m
    $202–460

  4. Shuttle to Miami International Airport, fly to Charlotte Douglas International Airport, bus

    1. Take a shuttle bus from Key Largo, FL to Miami, FL - International Airportshuttle bus
    2. Fly from Miami International Airport (MIA) to Charlotte Douglas International Airport (CLT)plane plane MIA - CLT
    3. Take the bus from Charlotte Bus Station to Camdenbus bus
    4. Take the bus from Camden to Columbia, SCbus bus
    10h 8m
    $286–574

  5. Shuttle to Fort Lauderdale–Hollywood International Airport, fly to Charlotte Douglas International Airport, bus

    1. Take a shuttle bus from Key Largo, FL to Fort Lauderdale, FL - International Airportshuttle bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Charlotte Douglas International Airport (CLT)plane plane FLL - CLT
    3. Take the bus from Charlotte Bus Station to Camdenbus bus
    4. Take the bus from Camden to Columbia, SCbus bus
    10h 40m
    $253–563

Key Largo to Columbia by bus and train

Calendar7Weekly Services
Duration20h 5mAverage Duration
Ticket$202Cheapest Price
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Comparing Your Travel Options

Map of how to get from Key Largo to Columbia.ExpandLaunch map view
  • Distance: 647.2 mi
  • Duration: 7h 31m

What companies run services between Key Largo, FL, USA and Columbia, SC, USA?

There is no direct connection from Key Largo to Columbia. However, you can take the shuttle to Miami, FL - International Airport, walk to Miami International Airport (MIA) airport, fly to Savannah (SAV), take the taxi to Savannah Station, then take the train to Columbia Station. Alternatively, you can take a bus from Key Largo Bus Stop to Columbia Station via Miami, Airport Intermodal Station, Miami Airport Station, Hollywood Station, and Hollywood Amtrak Station in around 20h 5m.

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