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How to get fromKey Largo to Columbiaby shuttle, plane, train, bus, bus (Greyhound, Flixbus), or car

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There are 7 ways to get from Key Largo to Columbia by shuttle, plane, train, bus, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Shuttle to Miami International Airport, fly to Savannah, train

    best
    1. Take a shuttle bus from Key Largo, FL to Miami, FL - International Airportshuttle bus
    2. Fly from Miami International Airport (MIA) to Savannah (SAV)plane plane MIA - SAV
    3. Take the train from Savannah Station to Columbia Stationtrain train
    7h 42m
    $265–676

  2. Drive 693.7 mi

    cheapest
    1. Drive from Key Largo to Columbiacar car 693.7 mi
    11h 32m
    $127–183

  3. Bus, train

    1. Take the bus from Key Largo Bus Stop to Miami Airport Stationbus bus Greyhound US0720s
    2. Take the train from Hollywood Amtrak Station to Columbia Stationtrain train Floridian
    20h 5m
    $268–540

  4. Bus

    1. Take the bus from Key Largo Bus Stop to Miami Airport Stationbus bus
    2. Take the bus from Miami Airport Station to Ft Lauderdale Broward Park & Ridebus bus
    3. Take the bus from Ft Lauderdale Broward Park & Ride to Savannah Bus Stationbus bus
    4. Take the bus from Savannah Bus Station to Sumter Bus Stopbus bus
    5. Take the bus from James E Clyburn Intermodal Transportation Center to Assembly Senate Northbus bus 44
    21h 19m
    $133–230

  5. Shuttle to Miami International Airport, fly to Charlotte Douglas International Airport, bus

    1. Take a shuttle bus from Key Largo, FL to Miami, FL - International Airportshuttle bus
    2. Fly from Miami International Airport (MIA) to Charlotte Douglas International Airport (CLT)plane plane MIA - CLT
    3. Take the bus from Charlotte Bus Station to Camdenbus bus
    4. Take the bus from Camden to Columbia, SCbus bus
    10h 15m
    $286–578

  6. Shuttle to Fort Lauderdale–Hollywood International Airport, fly to Charlotte Douglas International Airport, bus

    1. Take a shuttle bus from Key Largo, FL to Fort Lauderdale, FL - International Airportshuttle bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Charlotte Douglas International Airport (CLT)plane plane FLL - CLT
    3. Take the bus from Charlotte Bus Station to Camdenbus bus
    4. Take the bus from Camden to Columbia, SCbus bus
    10h 40m
    $248–547

  7. Shuttle to Miami International Airport, fly to Charleston International Airport, bus

    1. Take a shuttle bus from Key Largo, FL to Miami, FL - International Airportshuttle bus
    2. Fly from Miami International Airport (MIA) to Charleston International Airport (CHS)plane plane MIA - CHS
    3. Take the bus from Charleston Bus Station to Sumter Bus Stopbus bus
    4. Take the bus from James E Clyburn Intermodal Transportation Center to Assembly Senate Northbus bus
    13h 55m
    $641–1,182

Key Largo to Columbia by bus and train

Calendar7Weekly Services
Duration20h 5mAverage Duration
Ticket$268Cheapest Price
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Questions & Answers

Map of how to get from Key Largo to Columbia.ExpandLaunch map view
  • Distance: 647.2 mi
  • Duration: 7h 42m

What companies run services between Key Largo, FL, USA and Columbia, SC, USA?

You can take a bus from Key Largo Bus Stop to Assembly Senate North via Miami Airport Station, Ft Lauderdale Broward Park & Ride, Savannah Bus Station, Sumter Bus Stop, and James E Clyburn Intermodal Transportation Center in around 21h 19m.

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Train operators
Bus operators

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