There are 6 ways to get from Key Largo to Durham by shuttle, plane, bus (Greyhound, Flixbus), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Shuttle to Miami International Airport, fly to Raleigh-Durham International Airport
best- Take a shuttle bus from Key Largo, FL to Miami, FL - International Airport
- Fly from Miami International Airport (MIA) to Raleigh-Durham International Airport (RDU)plane MIA - RDU
5h 56m$216–632Bus
cheapest- Take the bus from Key Largo Bus Stop to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Orlando Bus Stationbus
- Take the bus from Orlando Bus Station to Raleigh Bus Stationbus
20h 31m$137–243Bus, train
- Take the bus from Key Largo Bus Stop to Miami Airport Stationbus Greyhound US0720s
- Take the train from Hollywood Amtrak Station to Carytrain Floridian
25h 36m$307–684Drive 861.2 mi
- Drive from Key Largo to Durhamcar 861.2 mi
14h 59m$158–227Shuttle to Fort Lauderdale–Hollywood International Airport, fly to Raleigh-Durham International Airport
- Take a shuttle bus from Key Largo, FL to Fort Lauderdale, FL - International Airport
- Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Raleigh-Durham International Airport (RDU)plane FLL - RDU
6h 13m$303–1,001Shuttle to Miami International Airport, fly to Piedmont Triad International Airport, train
- Take a shuttle bus from Key Largo, FL to Miami, FL - International Airport
- Fly from Miami International Airport (MIA) to Piedmont Triad International Airport (GSO)plane MIA - GSO
- Take the train from Greensboro to Durham Amtrak Stationtrain
6h 52m$275–846
Key Largo to Durham by bus
Questions & Answers
The cheapest way to get from Key Largo to Durham is to bus which costs $130 - $250 and takes 20h 31m.
The fastest way to get from Key Largo to Durham is to shuttle and fly which takes 5h 56m and costs $210 - $650.
No, there is no direct bus from Key Largo to Durham. However, there are services departing from Key Largo Bus Stop and arriving at Durham via Miami Airport Station, Orlando Bus Station and Raleigh Bus Station. The journey, including transfers, takes approximately 20h 31m.
The distance between Key Largo and Durham is 782 miles. The road distance is 866.2 miles.
The best way to get from Key Largo to Durham without a car is to bus which takes 20h 31m and costs $130 - $250.
It takes approximately 5h 56m to get from Key Largo to Durham, including transfers.
Key Largo to Durham bus services, operated by Greyhound USA, depart from Key Largo Bus Stop station.
Key Largo to Durham bus services, operated by Greyhound USA, arrive at Miami Airport Station.
Yes, the driving distance between Key Largo to Durham is 866 miles. It takes approximately 14h 59m to drive from Key Largo to Durham.
Book your Key Largo to Durham bus tickets online with Omio and FlixBus.
What companies run services between Key Largo, FL, USA and Durham, NC, USA?
You can take a bus from Key Largo Bus Stop to Durham via Miami Airport Station, Orlando Bus Station, and Raleigh Bus Station in around 20h 31m.
- Website
- aa.com
Flights from Miami International Airport to Raleigh-Durham International Airport
- Ave. Duration
- 2h 20m
- When
- Every day
- Estimated price
- $80–430
Flights from Miami International Airport to Raleigh-Durham International Airport via Charlotte
- Ave. Duration
- 4h 27m
- When
- Every day
- Estimated price
- $85–450
Flights from Fort Lauderdale–Hollywood International Airport to Raleigh-Durham International Airport via Charlotte
- Ave. Duration
- 4h 37m
- When
- Every day
- Estimated price
- $90–470
Flights from Miami International Airport to Piedmont Triad International Airport
- Ave. Duration
- 2h 21m
- When
- Every day
- Estimated price
- $120–650
Flights from Miami International Airport to Piedmont Triad International Airport via Charlotte
- Ave. Duration
- 5h 3m
- When
- Every day
- Estimated price
- $120–650
- Website
- delta.com
Flights from Miami International Airport to Raleigh-Durham International Airport
- Ave. Duration
- 2h 31m
- When
- Every day
- Estimated price
- $80–430
Flights from Fort Lauderdale–Hollywood International Airport to Raleigh-Durham International Airport
- Ave. Duration
- 2h 12m
- When
- Every day
- Estimated price
- $85–450
Flights from Fort Lauderdale–Hollywood International Airport to Raleigh-Durham International Airport via Atlanta
- Ave. Duration
- 4h 29m
- When
- Every day
- Estimated price
- $100–550
Flights from Miami International Airport to Piedmont Triad International Airport via Atlanta
- Ave. Duration
- 5h
- When
- Every day
- Estimated price
- $140–700
- Website
- southwest.com
Flights from Miami International Airport to Raleigh-Durham International Airport via Orlando
- Ave. Duration
- 4h
- When
- Monday, Thursday, Friday, and Saturday
- Estimated price
- $80–430
Flights from Fort Lauderdale–Hollywood International Airport to Raleigh-Durham International Airport
- Ave. Duration
- 2h
- When
- Sunday
- Estimated price
- $85–450
Flights from Fort Lauderdale–Hollywood International Airport to Raleigh-Durham International Airport via Orlando
- Ave. Duration
- 3h 53m
- When
- Monday to Wednesday
- Estimated price
- $85–460
- Website
- jetblue.com
Flights from Fort Lauderdale–Hollywood International Airport to Raleigh-Durham International Airport
- Ave. Duration
- 2h 3m
- When
- Every day
- Estimated price
- $85–450
- Website
- flyfrontier.com
Flights from Miami International Airport to Raleigh-Durham International Airport
- Ave. Duration
- 2h 16m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $100–440
Flights from Fort Lauderdale–Hollywood International Airport to Raleigh-Durham International Airport
- Ave. Duration
- 2h 13m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $130–460
- Website
- united.com
Flights from Miami International Airport to Piedmont Triad International Airport via Washington Dulles
- Ave. Duration
- 4h 50m
- When
- Saturday
- Estimated price
- $170–800
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Hollywood Amtrak Station to Cary
- Ave. Duration
- 20h 55m
- Frequency
- Once daily
- Estimated price
- $290–650
- Website
- Amtrak
Train from Greensboro to Durham Amtrak Station
- Ave. Duration
- 1h 1m
- Frequency
- 5 times a day
- Estimated price
- $16–35
- Website
- Amtrak
- Phone
- +1 (305) 289-9997
- [email protected]
- Website
- Keys Shuttle
Shuttle from Key Largo, FL to Miami, FL - International Airport
- Ave. Duration
- 1h 15m
- Frequency
- 3 times a day
- Estimated price
- $110–130
- Website
- Keys Shuttle
Shuttle from Key Largo, FL to Fort Lauderdale, FL - International Airport
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- $120–150
- Website
- Keys Shuttle
Shuttle from Key Largo, FL to Miami, FL - International Airport
- Ave. Duration
- 1h 15m
- Frequency
- 3 times a day
- Estimated price
- $110–130
- Website
- Keys Shuttle
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Key Largo Bus Stop to Miami Airport Station
- Ave. Duration
- 1h 20m
- Frequency
- 3 times a day
- Estimated price
- $8–17
- Website
- Greyhound
Bus from Miami Airport Station to Orlando Bus Station
- Ave. Duration
- 4h 50m
- Frequency
- 3 times a day
- Estimated price
- $35–70
- Website
- Greyhound
Bus from Key Largo Bus Stop to Miami Airport Station
- Ave. Duration
- 1h 20m
- Frequency
- 3 times a day
- Estimated price
- $8–17
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Miami Airport Station to Orlando Bus Station
- Ave. Duration
- 4h 45m
- Frequency
- Every 2 hours
- Estimated price
- $35–60
- Schedules at
- Flixbus USA
Bus from Orlando Bus Station to Raleigh Bus Station
- Ave. Duration
- 11h 5m
- Frequency
- 5 times a week
- Estimated price
- $90–150
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
There are 354+ hotels available in Durham.







