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How to get fromKey Largo to Knoxvilleby shuttle, plane, bus, train, bus (Greyhound, Flixbus), or car

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There are 10 ways to get from Key Largo to Knoxville by shuttle, plane, bus, train, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Shuttle to Miami International Airport, fly to Mcghee Tyson Airport

    best
    1. Take a shuttle bus from Key Largo, FL to Miami, FL - International Airportshuttle bus
    2. Fly from Miami International Airport (MIA) to Mcghee Tyson Airport (TYS)plane plane MIA - TYS
    4h 41m
    $285–846

  2. Drive 901.4 mi

    cheapest
    1. Drive from Key Largo to Knoxvillecar car 901.4 mi
    15h 55m
    $165–238

  3. Bus, train via Farragut

    1. Take the bus from Key Largo Bus Stop to Miami Airport Stationbus bus
    2. Take the train from Hollywood Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York to Knoxvillebus bus Nyc
    44h 17m
    $645–1,176

  4. Bus via Orlando

    1. Take the bus from Key Largo Bus Stop to Miami Airport Stationbus bus
    2. Take the bus from Miami Airport Station to Orlando Bus Stationbus bus
    3. Take the bus from Orlando Bus Station to New York City Chinatownbus bus
    4. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    46h 23m
    $313–492

  5. Shuttle to Fort Lauderdale–Hollywood International Airport, fly to Mcghee Tyson Airport

    1. Take a shuttle bus from Key Largo, FL to Fort Lauderdale, FL - International Airportshuttle bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Mcghee Tyson Airport (TYS)plane plane FLL - TYS
    5h 7m
    $312–915

  6. Bus to Key West International Airport, fly to Mcghee Tyson Airport

    1. Take the bus from Key Largo Bus Stop to Key West Airportbus bus
    2. Fly from Key West International Airport (EYW) to Mcghee Tyson Airport (TYS)plane plane EYW - TYS
    6h 37m
    $190–748

  7. Shuttle to Miami International Airport, fly to Asheville Regional Airport, drive

    1. Take a shuttle bus from Key Largo, FL to Miami, FL - International Airportshuttle bus
    2. Fly from Miami International Airport (MIA) to Asheville Regional Airport (AVL)plane plane MIA - AVL
    3. Drive from Asheville-Airport-AVL to Knoxvillecar car
    6h 40m
    $197–511

  8. Shuttle to Fort Lauderdale–Hollywood International Airport, fly to Asheville Regional Airport, drive

    1. Take a shuttle bus from Key Largo, FL to Fort Lauderdale, FL - International Airportshuttle bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Asheville Regional Airport (AVL)plane plane FLL - AVL
    3. Drive from Asheville-Airport-AVL to Knoxvillecar car
    6h 58m
    $219–560

  9. Bus, train

    1. Take the bus from Key Largo Bus Stop to Miami Airport Stationbus bus
    2. Take the train from Hollywood Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    44h 21m
    $600–1,086

  10. Bus

    1. Take the bus from Key Largo Bus Stop to Miami Airport Stationbus bus
    2. Take the bus from Miami Airport Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to New York City Chinatownbus bus
    4. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    2d 3h
    $348–572

Miami International Airport (MIA) to Mcghee Tyson Airport (TYS) flights

Calendar43Weekly Planes
Duration4h 2mAverage Duration
Ticket$126Cheapest Price
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Questions & Answers

Map of how to get from Key Largo to Knoxville.ExpandLaunch map view
  • Distance: 796.9 mi
  • Duration: 4h 41m

What companies run services between Key Largo, FL, USA and Knoxville, TN, USA?

You can take a bus from Key Largo Bus Stop to Knoxville Station Hall of Fame via Miami Airport Station, Orlando Bus Station, New York, NY, Knoxville, TN, Walmart, and Charlie Haun WB Aft Washington PK in around 46h 23m.

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