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How to get fromKey Largo to Panama City Beachby shuttle, plane, car, bus (Greyhound), bus, or train

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There are 9 ways to get from Key Largo to Panama City Beach by shuttle, plane, car, bus (Greyhound), bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Shuttle to Miami International Airport, fly to Destin–Fort Walton Beach Airport, drive

    best
    1. Take a shuttle bus from Key Largo, FL to Miami, FL - International Airportshuttle bus
    2. Fly from Miami International Airport (MIA) to Destin–Fort Walton Beach Airport (VPS)plane plane MIA - VPS
    3. Drive from Destin–Fort Walton Beach Airport (VPS) to Panama City Beachcar car
    5h 23m
    $175–482

  2. Drive  610 mi

    cheapest
    1. Drive from Key Largo to Panama City Beachcar car 610 mi
    11h 45m
    $112–161

  3. Bus via Miami Airport (MIA)

    1. Take the bus from Key Largo Bus Stop to Miami Airport Stationbus bus
    2. Take the bus from Miami Airport to Tallahassee - FSU - Old St Augustine at Intramural Fieldbus bus
    3. Take the bus from Tallahassee to Panama City Beach Bus Stationbus bus
    15h 39m
    $156–224

  4. Bus, train

    1. Take the bus from Key Largo Bus Stop to Miami Airport Stationbus bus
    2. Take the train from Hollywood Amtrak Station to Jacksonvilletrain train
    3. Take the bus from Jacksonville to Tallahasseebus bus
    4. Take the bus from Tallahassee to Panama City Beach Bus Stationbus bus
    19h 19m
    $170–349

  5. Shuttle to Miami International Airport, fly to Northwest Florida Beaches International Airport

    1. Take a shuttle bus from Key Largo, FL to Miami, FL - International Airportshuttle bus
    2. Fly from Miami International Airport (MIA) to Northwest Florida Beaches International Airport (ECP)plane plane MIA - ECP
    6h 50m
    $235–601

  6. Shuttle to Fort Lauderdale–Hollywood International Airport, fly to Northwest Florida Beaches International Airport

    1. Take a shuttle bus from Key Largo, FL to Fort Lauderdale, FL - International Airportshuttle bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Northwest Florida Beaches International Airport (ECP)plane plane FLL - ECP
    7h 13m
    $262–660

  7. Shuttle to Miami International Airport, fly to Tallahassee, bus

    1. Take a shuttle bus from Key Largo, FL to Miami, FL - International Airportshuttle bus
    2. Fly from Miami International Airport (MIA) to Tallahassee (TLH)plane plane MIA - TLH
    3. Take the bus from Tallahassee to Panama City Beach Bus Stationbus bus
    7h 7m
    $223–612

  8. Shuttle to Miami International Airport, fly to Pensacola International Airport, bus

    1. Take a shuttle bus from Key Largo, FL to Miami, FL - International Airportshuttle bus
    2. Fly from Miami International Airport (MIA) to Pensacola International Airport (PNS)plane plane MIA - PNS
    3. Take the bus from Pensacola Airport to Panama City Beach Bus Stationbus bus
    7h 31m
    $179–443

  9. Bus (Greyhound)

    1. Take the bus from Key Largo Bus Stop to Miami Airport Stationbus bus
    2. Take the bus from Miami Airport Station to Tallahasseebus bus
    3. Take the bus from Tallahassee to Panama City Beach Bus Stationbus bus
    19h 29m
    $119–192

Miami International Airport (MIA) to Destin–Fort Walton Beach Airport (VPS) flights

Calendar14Weekly Planes
Duration2h 57mAverage Duration
Ticket$57Cheapest Price
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Comparing Your Travel Options

Map of how to get from Key Largo to Panama City Beach.ExpandLaunch map view
  • Distance: 619 mi
  • Duration: 5h 23m

What companies run services between Key Largo, FL, USA and Panama City Beach, FL, USA?

You can take a bus from Key Largo Bus Stop to Panama City Beach via Miami, Airport Intermodal Station, Miami Airport Station, Miami International Airport, Miami Airport, Old St Augustine at Intramural Field, Tallahassee, and Panama City Beach Bus Station in around 15h 39m.

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