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How to get fromKey Largo to Sanibelby bus, taxi, ferry, car, or bus (Greyhound, Flixbus)

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There are 4 ways to get from Key Largo to Sanibel by bus, taxi, ferry, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, taxi

    best
    1. Take the bus from Key Largo Bus Stop to Miami Airport Stationbus bus
    2. Take the bus from Miami Airport to Naples, FLbus bus
    3. Take the taxi from Naples, FL to Sanibeltaxi taxi
    5h 29m
    $179–247

  2. Drive 182.5 mi

    cheapest
    1. Drive from Key Largo to Sanibelcar car 182.5 mi
    3h 56m
    $34–49

  3. Bus, ferry

    1. Take the bus from Key Largo Bus Stop to Big Pine Keybus bus
    2. Take the bus from Big Pine Key - CVS / MM30 to Caroline & Grinnellbus bus Lks
    3. Take the ferry from Key West, FL to Fort Myers Beach, FLferry ferry
    9h 53m
    $178–199

  4. Bus

    1. Take the bus from Key Largo Bus Stop to Miami Airport Stationbus bus Greyhound US0720s
    2. Take the bus from Miami Airport Station to Fort Myers Bus Stopbus bus FlixBus 2421
    7h 36m
    $80–125

Questions & Answers

Map of how to get from Key Largo to Sanibel.ExpandLaunch map view
  • Distance: 233.3 mi
  • Duration: 5h 29m

What companies run services between Key Largo, FL, USA and Sanibel, FL, USA?

You can take a bus from Key Largo Bus Stop to Sanibel via Miami Airport Station, Rosa Parks Transportation Ctr, and Cape Coral Transfer Center in around 7h 36m.

Bus operators
Ferry operators
Other operators

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