What is the cheapest way to get from Key Largo to Sanibel Island?

The cheapest way to get from Key Largo to Sanibel Island is to drive which costs $30 - $50 and takes 3h 54m.

What is the fastest way to get from Key Largo to Sanibel Island?

The fastest way to get from Key Largo to Sanibel Island is to drive which takes 3h 54m and costs $30 - $50.

Is there a direct bus between Key Largo and Sanibel Island?

No, there is no direct bus from Key Largo to Sanibel Island. However, there are services departing from Key Largo Bus Stop and arriving at Fort Myers via Miami Airport. The journey, including transfers, takes approximately 5h 55m.

How far is it from Key Largo to Sanibel Island?

The distance between Key Largo and Sanibel Island is 251 miles. The road distance is 182.5 miles.

How do I travel from Key Largo to Sanibel Island without a car?

The best way to get from Key Largo to Sanibel Island without a car is to bus which takes 5h 55m and costs $130 - $210.

How long does it take to get from Key Largo to Sanibel Island?

It takes approximately 5h 55m to get from Key Largo to Sanibel Island, including transfers.

Where do I catch the Key Largo to Sanibel Island bus from?

Key Largo to Sanibel Island bus services, operated by Greyhound USA, depart from Key Largo Bus Stop station.

Where does the Key Largo to Sanibel Island bus arrive?

Key Largo to Sanibel Island bus services, operated by Greyhound USA, arrive at Miami Airport Station.

Can I drive from Key Largo to Sanibel Island?

Yes, the driving distance between Key Largo to Sanibel Island is 183 miles. It takes approximately 3h 54m to drive from Key Largo to Sanibel Island.

Where can I stay near Sanibel Island?

There are 4246+ hotels available in Sanibel Island.

Key Largo to Sanibel Island - 6 ways to travel via bus, ferry, car, and shuttle

How to get fromKey Largo to Sanibel Island

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There are 6 ways to get from Key Largo to Sanibel Island by bus (Greyhound), bus, ferry, car, shuttle, plane, taxi, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Bus
best
1. Take the bus from Key Largo Bus Stop to Miami Airport Stationbus Greyhound US0720s
2. Take the bus from Miami Airport to Fort Myersbus Miami–Tampa / ...
5h 55m
$135–204
Drive 181.4 mi
cheapest
1. Drive from Key Largo to Sanibel Islandcar 181.4 mi
3h 54m
$34–48
Bus, ferry
1. Take the bus from Key Largo Bus Stop to Big Pine Keybus
2. Take the bus from Big Pine Key - CVS / MM30 to Caroline & Grinnellbus Lks
3. Take the ferry from Key West, FL to Fort Myers Beach, FLferry
9h 51m
$189–216
Shuttle, fly, bus
1. Take a shuttle bus from Key Largo, FL to Miami, FL - International Airportshuttle
2. Fly from Miami International Airport (MIA) to Tampa (TPA)plane MIA - TPA
3. Take the bus from Tampa Airport to Fort Myersbus
7h 35m
$960–1,376
Bus, taxi
1. Take the bus from Key Largo Bus Stop to Miami Airport Stationbus
2. Take the bus from Fort Lauderdale Airport to Naplesbus
3. Take the taxi from Naples to Sanibel Islandtaxi
6h 18m
$183–260
Bus via Cape Coral Transfer Center
1. Take the bus from Key Largo Bus Stop to Miami Airport Stationbus Greyhound US0720s
2. Take the bus from Miami Airport Station to Fort Myers Bus Stopbus FlixBus 2421
7h 38m
$96–137

Miami International Airport (MIA) to Tampa (TPA) flights

47Weekly Planes

1h 12mAverage Duration

$40Cheapest Price

See schedules

Questions & Answers

Map of how to get from Key Largo to Sanibel Island.

Launch map view

Distance: 249.3 mi
Duration: 5h 55m

What companies run services between Key Largo, FL, USA and Sanibel Island, FL, USA?

You can take a bus from Key Largo Bus Stop to Sanibel Island via Miami, Airport Intermodal Station, Miami Airport Station, Miami International Airport, Miami Airport, and Fort Myers in around 5h 55m.

Airlines

Bus operators

Ferry operators

Other operators

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How to get fromKey Largo to Sanibel Islandby bus (Greyhound), bus, ferry, car, shuttle, plane, taxi, or bus (Greyhound, Flixbus)

There are 6 ways to get from Key Largo to Sanibel Island by bus (Greyhound), bus, ferry, car, shuttle, plane, taxi, or bus (Greyhound, Flixbus)

Bus

Drive 181.4 mi

Bus, ferry

Shuttle, fly, bus

Bus, taxi

Bus via Cape Coral Transfer Center