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How to get fromKey Largo to St. Petersburgby bus, train, bus (Greyhound, Flixbus), car, shuttle, or plane

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There are 10 ways to get from Key Largo to St. Petersburg by bus, train, bus (Greyhound, Flixbus), car, shuttle, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train

    best
    1. Take the bus from Key Largo Bus Stop to Miami Airport Stationbus bus Greyhound US0720s
    2. Take the train from Hollywood Amtrak Station to Tampatrain train Floridian
    8h 53m
    $141–252

  2. Bus

    cheapest
    1. Take the bus from Key Largo Bus Stop to Miami Airport Stationbus bus
    2. Take the bus from Miami Airport Station to Sarasota Cattlemen Transfer Centerbus bus
    3. Take the bus from Desoto Station Parking For 12 & 203 to 34Th St S Nb/1St Av Sbus bus 203
    11h 32m
    $40–88

  3. Drive 287.1 mi

    1. Drive from Key Largo to St. Petersburgcar car 287.1 mi
    5h 19m
    $53–76

  4. Shuttle to Miami International Airport, fly to Tampa

    1. Take a shuttle bus from Key Largo, FL to Miami, FL - International Airportshuttle bus
    2. Fly from Miami International Airport (MIA) to Tampa (TPA)plane plane MIA - TPA
    6h 15m
    $766–1,232

  5. Bus, train via Fort Lauderdale

    1. Take the bus from Key Largo Bus Stop to Miami Airport Stationbus bus
    2. Take the train from Miami Airport Station to Fort Lauderdale Stationtrain train
    3. Take the bus from Ft Lauderdale Broward Park & Ride to Tampa Bus Stationbus bus
    4. Take the bus from Marion Transit Parking Lot to 2Nd Ave Ne + Beach Drivebus bus 100
    14h 2m
    $58–103

  6. Shuttle to Fort Lauderdale–Hollywood International Airport, fly to Tampa

    1. Take a shuttle bus from Key Largo, FL to Fort Lauderdale, FL - International Airportshuttle bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Tampa (TPA)plane plane FLL - TPA
    6h 48m
    $233–651

  7. Shuttle to Miami International Airport, fly to Sarasota–Bradenton International Airport

    1. Take a shuttle bus from Key Largo, FL to Miami, FL - International Airportshuttle bus
    2. Fly from Miami International Airport (MIA) to Sarasota–Bradenton International Airport (SRQ)plane plane MIA - SRQ
    6h 17m
    $167–536

  8. Bus to Key West International Airport, fly to Saint Petersburg–Clearwater International Airport

    1. Take the bus from Key Largo Bus Stop to Key West Airportbus bus
    2. Fly from Key West International Airport (EYW) to Saint Petersburg–Clearwater International Airport (PIE)plane plane EYW - PIE
    7h 4m
    $60–322

  9. Bus to Key West International Airport, fly to Tampa

    1. Take the bus from Key Largo Bus Stop to Key West Airportbus bus
    2. Fly from Key West International Airport (EYW) to Tampa (TPA)plane plane EYW - TPA
    8h 13m
    $85–422

  10. Shuttle to Miami International Airport, fly to Orlando, Amtrak Thruway

    1. Take a shuttle bus from Key Largo, FL to Miami, FL - International Airportshuttle bus
    2. Fly from Miami International Airport (MIA) to Orlando (MCO)plane plane MIA - MCO
    3. Take the bus from Orlando, FL to St. Petersburgbus bus
    8h 50m
    $747–1,279

Key Largo to St. Petersburg by bus

Calendar10Weekly Buses
Duration11h 32mAverage Duration
Ticket$40Cheapest Price
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Questions & Answers

Map of how to get from Key Largo to St. Petersburg.ExpandLaunch map view
  • Distance: 340.6 mi
  • Duration: 8h 53m

What companies run services between Key Largo, FL, USA and St. Petersburg, FL, USA?

You can take a bus from Key Largo Bus Stop to 34Th St S Nb/1St Av S via Miami Airport Station, Sarasota Cattlemen Transfer Center, Cattlemen Transit Station, Downtown Transfer Station, 301 Blvd W @ 9Th St Ext Ns, and Desoto Station Parking For 12 & 203 in around 11h 32m.

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