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How to get fromKey West, FL to Jacksonvilleby plane, bus (Greyhound, Flixbus), bus, train, car, or ferry

Find Transport to Jacksonville

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There are 6 ways to get from Key West, FL to Jacksonville by plane, bus (Greyhound, Flixbus), bus, train, car, or ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Jacksonville

    best
    1. Fly from Key West International Airport (EYW) to Jacksonville (JAX)plane plane EYW - JAX
    6h 3m
    $137–450

  2. Bus

    cheapest
    1. Take the bus from Whitehead & Eaton to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Jacksonvillebus bus
    15h 48m
    $82–149

  3. Bus, train

    1. Take the bus from Whitehead & Eaton to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the train from Miami Airport Station to Fort Lauderdale Stationtrain train
    4. Take the train from Fort Lauderdale Amtrak Station to Jacksonvilletrain train
    16h 51m
    $127–278

  4. Drive  504.3 mi

    1. Drive from Key West, FL to Jacksonvillecar car 504.3 mi
    9h 12m
    $92–133

  5. Fly to Orlando Sanford, drive

    1. Fly from Key West International Airport (EYW) to Orlando Sanford (SFB)plane plane EYW - SFB
    2. Drive from Orlando-Sanford-Airport-SFB to Jacksonvillecar car
    4h 35m
    $138–412

  6. Ferry, bus

    1. Take the ferry from Key West, FL to Fort Myers Beach, FLferry ferry
    2. Take the bus from Fort Myers Bus Stop to Orlando Bus Stationbus bus
    3. Take the bus from Orlando Bus Station to Jacksonvillebus bus
    17h 31m
    $184–224

Key West, FL to Jacksonville by bus and foot

Calendar19Weekly Services
Duration15h 48mAverage Duration
Ticket$82Cheapest Price
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Comparing Your Travel Options

Map of how to get from Key West, FL to Jacksonville.ExpandLaunch map view
  • Distance: 432.1 mi
  • Duration: 6h 3m

What companies run services between Key West, FL, USA and Jacksonville, FL, USA?

American Airlines and Delta fly from Key West International Airport (EYW) to Jacksonville (JAX) every 4 hours. Alternatively, you can take a bus from Whitehead & Eaton to Jacksonville via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, and Miami Airport Station in around 15h 48m.

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