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How to get fromKey West, FL to New Orleansby plane, ferry, bus, car, shuttle, train, or bus (Greyhound, Flixbus)

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There are 8 ways to get from Key West, FL to New Orleans by plane, ferry, bus, car, shuttle, train, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Key West International Airport to Louis Armstrong New Orleans International Airport

    best
    1. Fly from Key West International Airport (EYW) to Louis Armstrong New Orleans International Airport (MSY)plane plane EYW - MSY
    6h 35m
    $177–690

  2. Drive  1,003.1 mi

    cheapest
    1. Drive from Key West, FL to New Orleanscar car 1,003.1 mi
    17h 53m
    $172–248

  3. Ferry, bus

    1. Take the ferry from Key West, FL to Fort Myers Beach, FLferry ferry
    2. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    3. Take the bus from Tampa Bus Station to Tallahasseebus bus
    4. Take the bus from Tallahassee to Mobile Bus Stationbus bus
    5. Take the bus from Mobile Bus Station to New Orleans Bus Stationbus bus
    25h 6m
    $297–395

  4. Shuttle to Miami International Airport, fly to Louis Armstrong New Orleans International Airport

    1. Take a shuttle bus from Key West, FL to Miami, FL - International Airportshuttle bus
    2. Fly from Miami International Airport (MIA) to Louis Armstrong New Orleans International Airport (MSY)plane plane MIA - MSY
    8h 25m
    $774–1,301

  5. Fly Key West International Airport to Gulfport-Biloxi Regional Airport, train

    1. Fly from Key West International Airport (EYW) to Gulfport-Biloxi Regional Airport (GPT)plane plane EYW - GPT
    2. Take the train from Gulfport, MS to New Orleans, LA - Union Passenger Terminaltrain train
    8h 22m
    $218–618

  6. Shuttle to Fort Lauderdale–Hollywood International Airport, fly to Louis Armstrong New Orleans International Airport

    1. Take a shuttle bus from Key West, FL to Fort Lauderdale, FL - International Airportshuttle bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Louis Armstrong New Orleans International Airport (MSY)plane plane FLL - MSY
    8h 46m
    $291–820

  7. Shuttle, bus

    1. Take a shuttle bus from Key West, FL to Miami, FL - International Airportshuttle bus
    2. Take the bus from Miami Airport to Tallahassee - FSU - Old St Augustine at Intramural Fieldbus bus
    3. Take the bus from Tallahassee to Mobile Bus Stationbus bus
    4. Take the bus from Mobile Bus Station to New Orleans Bus Stationbus bus
    25h 19m
    $362–485

  8. Bus

    1. Take the bus from Whitehead & Eaton to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Tallahasseebus bus
    4. Take the bus from Tallahassee to Mobile Bus Stationbus bus
    5. Take the bus from Mobile Bus Station to New Orleans Bus Stationbus bus
    30h 53m
    $192–314

Key West, FL to New Orleans by bus and foot

Calendar14Weekly Services
Duration30h 53mAverage Duration
Ticket$192Cheapest Price
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Comparing Your Travel Options

Map of how to get from Key West, FL to New Orleans.ExpandLaunch map view
  • Distance: 659.1 mi
  • Duration: 6h 35m

What companies run services between Key West, FL, USA and New Orleans, LA, USA?

American Airlines, Delta, and two other airlines fly from Key West International Airport (EYW) to Louis Armstrong New Orleans International Airport (MSY) every 4 hours. Alternatively, you can take a bus from Whitehead & Eaton to New Orleans Bus Station via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, Tallahassee, and Mobile Bus Station in around 30h 53m.

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