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How to get fromKey West, FL to Orlandoby plane, shuttle, bus, train, car, or bus (Greyhound, Flixbus)

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There are 8 ways to get from Key West, FL to Orlando by plane, shuttle, bus, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Orlando

    best
    1. Fly from Key West International Airport (EYW) to Orlando (MCO)plane plane EYW - MCO
    2h 45m
    $148–739

  2. Bus

    cheapest
    1. Take the bus from Whitehead & Eaton to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Orlandobus bus
    11h 20m
    $52–96

  3. Shuttle, bus

    1. Take a shuttle bus from Key West, FL to Miami, FL - International Airportshuttle bus To the Airports
    2. Take the bus from Miami International Airport to Orlandobus bus Miami to Orlando
    10h 35m
    $208–248

  4. Bus, train

    1. Take the bus from Whitehead & Eaton to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the train from Hollywood Amtrak Station to Orlandotrain train
    12h 34m
    $93–205

  5. Drive 371.9 mi

    1. Drive from Key West, FL to Orlandocar car 371.9 mi
    7h 46m
    $68–98

  6. Fly to Orlando Sanford

    1. Fly from Key West International Airport (EYW) to Orlando Sanford (SFB)plane plane EYW - SFB
    2h 53m
    $181–462

  7. Fly to Tampa, train

    1. Fly from Key West International Airport (EYW) to Tampa (TPA)plane plane EYW - TPA
    2. Take the train from Tampa to Orlandotrain train
    6h 20m
    $172–543

  8. Bus, train via West Palm Beach

    1. Take the bus from Whitehead & Eaton to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the train from Miami Airport Station to West Palm Beach Stationtrain train
    4. Take the bus from West Palm Beach, FL to Orlando - RedCoach Station, FLbus bus
    11h 40m
    $65–125

Key West, FL to Orlando by shuttle and bus

Calendar14Weekly Services
Duration10h 35mAverage Duration
Ticket$208Cheapest Price
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Questions & Answers

Map of how to get from Key West, FL to Orlando.ExpandLaunch map view
  • Distance: 279.2 mi
  • Duration: 2h 45m

What companies run services between Key West, FL, USA and Orlando, FL, USA?

Breeze Airways flies from Key West International Airport (EYW) to Orlando (MCO) 4 times a week. Alternatively, you can take a bus from Whitehead & Eaton to Mccoy Rd & Central Ave via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, Orlando, and Florida Mall in around 11h 20m.

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