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How to get fromKey West (Island) to Jacksonvilleby plane, bus, train, car, shuttle, bus (Greyhound, Flixbus), or ferry

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There are 8 ways to get from Key West (Island) to Jacksonville by plane, bus, train, car, shuttle, bus (Greyhound, Flixbus), or ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Jacksonville

    best
    1. Fly from Key West International Airport (EYW) to Jacksonville (JAX)plane plane EYW - JAX
    5h 4m
    $72–420
  2. Fly to Orlando Sanford, drive

    cheapest
    1. Fly from Key West International Airport (EYW) to Orlando Sanford (SFB)plane plane EYW - SFB
    2. Drive from Orlando-Sanford-Airport-SFB to Jacksonvillecar car
    3h 33m
    $71–355
  3. Bus, train via Orlando

    1. Take the bus from Key West Airport to Miami Airport Stationbus bus
    2. Take the train from Miami Airport Station to Fort Lauderdale Stationtrain train
    3. Take the bus from Ft Lauderdale Broward Park & Ride to Orlando Bus Stationbus bus
    4. Take the bus from Orlando Bus Station to Jacksonvillebus bus
    13h 44m
    $84–143
  4. Bus, train

    1. Take the bus from Key West Airport to Miami Airport Stationbus bus Greyhound US0720s
    2. Take the train from Hollywood Amtrak Station to Jacksonvilletrain train Silver Meteor / ...
    14h 50m
    $254–405
  5. Drive  502.8 mi

    1. Drive from Key West to Jacksonvillecar car 502.8 mi
    9h 8m
    $86–125
  6. Shuttle, bus

    1. Take a shuttle bus from Key West, FL to Miami, FL - International Airportshuttle bus
    2. Take the bus from Miami Airport to Orlando - RedCoach Station, FLbus bus
    3. Take the bus from Orlando Bus Station to Jacksonvillebus bus
    14h 9m
    $252–315
  7. Bus

    1. Take the bus from Key West Airport to Miami Airport Stationbus bus Greyhound US0720s
    2. Take the bus from Miami Airport Station to Jacksonvillebus bus FlixBus 2431 / ...
    14h 25m
    $93–162
  8. Ferry, bus

    1. Take the ferry from Key West, FL to Fort Myers Beach, FLferry ferry
    2. Take the bus from Fort Myers Bus Stop to Orlando Bus Stationbus bus
    3. Take the bus from Orlando Bus Station to Jacksonvillebus bus
    16h 45m
    $190–229

Key West (Island) to Jacksonville by bus, train, and foot

Calendar19Weekly Services
Duration13h 44mAverage Duration
Ticket$84Cheapest Price
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Comparing Your Travel Options

What companies run services between Key West (Island), FL, USA and Jacksonville, FL, USA?

American Airlines and Delta fly from Key West International Airport (EYW) to Jacksonville (JAX) every 4 hours. Alternatively, you can take a bus from Key West Airport to Jacksonville via Miami Airport Station in around 14h 25m.

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Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

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