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How to get fromKey West (Island) to Louisvilleby plane, bus (Greyhound, Flixbus, Amtrak), car, bus, or shuttle

Find Transport to Louisville

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There are 6 ways to get from Key West (Island) to Louisville by plane, bus (Greyhound, Flixbus, Amtrak), car, bus, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Louisville International Airport

    best
    1. Fly from Key West International Airport (EYW) to Louisville International Airport (SDF)plane plane EYW - SDF
    5h 38m
    $160–796

  2. Fly to Blue Grass Airport, drive

    cheapest
    1. Fly from Key West International Airport (EYW) to Blue Grass Airport (LEX)plane plane EYW - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    5h 10m
    $104–476

  3. Bus

    1. Take the bus from Key West Airport to Miami Airport Stationbus bus
    2. Take the bus from Miami Airport Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Nashville Bus Stationbus bus
    4. Take the bus from Nashville to Louisville, KYbus bus
    28h 30m
    $190–324

  4. Drive  1,174.7 mi

    1. Drive from Key West to Louisvillecar car 1,174.7 mi
    22h 8m
    $215–310

  5. Fly to Evansville, bus

    1. Fly from Key West International Airport (EYW) to Evansville (EVV)plane plane EYW - EVV
    2. Take the bus from Evansville, IN to Louisville, KYbus bus
    8h 25m
    $149–621

  6. Shuttle, bus

    1. Take a shuttle bus from Key West, FL to Miami, FL - International Airportshuttle bus
    2. Take the bus from Miami Airport to Tallahassee - FSU - Old St Augustine at Intramural Fieldbus bus
    3. Take the bus from Tallahassee to Nashville Bus Stationbus bus
    4. Take the bus from Nashville to Louisville, KYbus bus
    30h 49m
    $405–550

Key West (Island) to Louisville by bus

Calendar14Weekly Buses
Duration28h 30mAverage Duration
Ticket$190Cheapest Price
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Comparing Your Travel Options

Map of how to get from Key West (Island) to Louisville.ExpandLaunch map view
  • Distance: 976.7 mi
  • Duration: 5h 38m

What companies run services between Key West (Island), FL, USA and Louisville, KY, USA?

Delta, American Airlines, and Breeze Airways fly from Key West International Airport (EYW) to Louisville International Airport (SDF) every 4 hours. Alternatively, you can take a bus from Key West Airport to Louisville, KY via Miami Airport Station, Atlanta Bus Station, and Nashville in around 28h 30m.

Airlines
Bus operators

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