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How to get fromKey West (Island) to San Franciscoby plane, bus (Greyhound, Flixbus), shuttle, train, or car

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There are 7 ways to get from Key West (Island) to San Francisco by plane, bus (Greyhound, Flixbus), shuttle, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to San Francisco International Airport

    best
    1. Fly from Key West International Airport (EYW) to San Francisco International Airport (SFO)plane plane EYW - SFO
    8h 56m
    $145–525

  2. Fly to Sonoma County Airport, shuttle

    cheapest
    1. Fly from Key West International Airport (EYW) to Sonoma County Airport (STS)plane plane EYW - STS
    2. Take a shuttle bus from Santa Rosa Airport to San Francisco Pier 27shuttle bus
    21h 37m
    $142–503

  3. Bus

    1. Take the bus from Key West Airport to Miami Airport Stationbus bus
    2. Take the bus from Miami Airport Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Dallas Bus Stationbus bus
    4. Take the bus from Dallas Bus Station to Los Angeles Union Stationbus bus
    5. Take the bus from Los Angeles Union Station to San Francisco Bus Stationbus bus
    3d 5h
    $514–1,025

  4. Shuttle, train

    1. Take a shuttle bus from Key West, FL to Miami, FL - International Airportshuttle bus
    2. Take the train from Miami Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Richmondtrain train
    4d 10h
    $1,602–3,235

  5. Drive 3,165.5 mi

    1. Drive from Key West to San Franciscocar car 3,165.5 mi
    2d 5h
    $578–835

  6. Fly to Norman Y. Mineta San José International Airport, Caltrain

    1. Fly from Key West International Airport (EYW) to Norman Y. Mineta San José International Airport (SJC)plane plane EYW - SJC
    2. Take the train from Santa Clara Caltrain Northbound to San Francisco Caltrain Northboundtrain train
    9h 50m
    $209–763

  7. Fly to Sacramento International Airport, train

    1. Fly from Key West International Airport (EYW) to Sacramento International Airport (SMF)plane plane EYW - SMF
    2. Take the train from Sacramento to Richmondtrain train
    12h 5m
    $243–873

Key West (Island) to San Francisco by bus

Calendar10Weekly Buses
Duration3d 5hAverage Duration
Ticket$514Cheapest Price
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Questions & Answers

Map of how to get from Key West (Island) to San Francisco.ExpandLaunch map view
  • Distance: 2,558.7 mi
  • Duration: 8h 56m

What companies run services between Key West (Island), FL, USA and San Francisco, CA, USA?

Delta and American Airlines fly from Key West International Airport (EYW) to San Francisco International Airport (SFO) every 4 hours. Alternatively, you can take a bus from Key West Airport to San Francisco Bus Station via Miami Airport Station, Atlanta Bus Station, Dallas Bus Station, and Los Angeles Union Station in around 3d 5h.

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