There are 8 ways to get from Key West to Boston by plane, bus, bus (Greyhound, Flixbus), shuttle, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Manchester Airport, bus
best- Fly from Key West International Airport (EYW) to Manchester Airport (MHT)plane EYW - MHT
- Take the bus from Boston Manchester Airport to Bostonbus
7h 58m$131–578Fly to Theodore Francis Green State Airport, train
cheapest- Fly from Key West International Airport (EYW) to Theodore Francis Green State Airport (PVD)plane EYW - PVD
- Take the train from TF Green Airport to South Stationtrain
8h 4m$106–420Bus
- Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus Lks
- Take the bus from Big Pine Key to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Newark Penn Stationbus
- Take the bus from Newark Penn Station to Bostonbus
38h 12m$275–419Shuttle, train
- Take a shuttle bus from Key West, FL to Miami, FL - International Airport
- Take the train from Miami Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain
38h 31m$1,067–1,634Drive 1,637.9 mi
- Drive from Key West to Bostoncar 1,637.9 mi
28h 53m$299–432Fly to Worcester Regional Airport, bus
- Fly from Key West International Airport (EYW) to Worcester Regional Airport (ORH)plane EYW - ORH
- Take the bus from Worcester Union Station to Bostonbus
18h 49m$130–580Fly to Laguardia Airport, train
- Fly from Key West International Airport (EYW) to Laguardia Airport (LGA)plane EYW - LGA
- Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain
8h 34m$275–920Fly to Newark Liberty International Airport, train
- Fly from Key West International Airport (EYW) to Newark Liberty International Airport (EWR)plane EYW - EWR
- Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain
8h 28m$239–653
Key West to Boston by bus and foot
Comparing Your Travel Options
The cheapest way to get from Key West to Boston is to fly and train which costs $100 - $420 and takes 8h 4m.
The fastest way to get from Key West to Boston is to fly and bus which takes 7h 58m and costs $130 - $600.
No, there is no direct bus from Key West to Boston. However, there are services departing from N Roosevelt & 3rd Street and arriving at Boston via Big Pine Key, Miami Airport Station and Newark Penn Station. The journey, including transfers, takes approximately 38h 12m.
The distance between Key West and Boston is 1461 miles. The road distance is 1647.5 miles.
The best way to get from Key West to Boston without a car is to bus which takes 38h 12m and costs $270 - $420.
It takes approximately 7h 58m to get from Key West to Boston, including transfers.
Key West to Boston bus services, operated by Key West Transit, depart from N Roosevelt & 3rd Street station.
Key West to Boston bus services, operated by Key West Transit, arrive at Big Pine Key - Auto Store / NAPA MM30 station.
Yes, the driving distance between Key West to Boston is 1647 miles. It takes approximately 28h 53m to drive from Key West to Boston.
Book your Key West to Boston bus tickets online with Omio.
What companies run services between Key West, FL, USA and Boston, MA, USA?
You can take a bus from N Roosevelt & 3rd Street to Boston via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, and Newark Penn Station in around 38h 12m.
- Website
- aa.com
Flights from Key West International Airport to Manchester Airport via Reagan Washington
- Ave. Duration
- 5h 23m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–550
Flights from Key West International Airport to Manchester Airport via Philadelphia
- Ave. Duration
- 6h 1m
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- $110–550
Flights from Key West International Airport to Manchester Airport via Charlotte
- Ave. Duration
- 6h 8m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–550
Flights from Key West International Airport to Manchester Airport via Chicago O'Hare
- Ave. Duration
- 10h 59m
- When
- Every day
- Estimated price
- $150–650
Flights from Key West International Airport to Theodore Francis Green State Airport via Charlotte
- Ave. Duration
- 5h 44m
- When
- Every day
- Estimated price
- $85–400
Flights from Key West International Airport to Theodore Francis Green State Airport via Reagan Washington
- Ave. Duration
- 6h 16m
- When
- Friday and Saturday
- Estimated price
- $85–390
Flights from Key West International Airport to Worcester Regional Airport via Philadelphia
- Ave. Duration
- 23h 14m
- When
- Every day
- Estimated price
- $110–550
Flights from Key West International Airport to Worcester Regional Airport via Miami, Philadelphia
- Ave. Duration
- 20h 46m
- When
- Every day
- Estimated price
- $110–550
Flights from Key West International Airport to Laguardia Airport
- Ave. Duration
- 3h 23m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–700
Flights from Key West International Airport to Laguardia Airport via Miami
- Ave. Duration
- 5h 14m
- When
- Every day
- Estimated price
- $140–700
Flights from Key West International Airport to Newark Liberty International Airport via Miami
- Ave. Duration
- 5h 27m
- When
- Every day
- Estimated price
- $85–410
- Website
- delta.com
Flights from Key West International Airport to Worcester Regional Airport via Laguardia Airport
- Ave. Duration
- 25h 27m
- When
- Monday, Tuesday, Wednesday, Thursday, Saturday, and Sunday
- Estimated price
- $110–550
Flights from Key West International Airport to Worcester Regional Airport via Miami, Laguardia Airport
- Ave. Duration
- 19h 24m
- When
- Monday, Tuesday, Wednesday, Thursday, Saturday, and Sunday
- Estimated price
- $110–550
Flights from Key West International Airport to Laguardia Airport
- Ave. Duration
- 3h 10m
- When
- Every day
- Estimated price
- $140–700
Flights from Key West International Airport to Newark Liberty International Airport via Atlanta
- Ave. Duration
- 6h 7m
- When
- Every day
- Estimated price
- $95–440
- Website
- united.com
Flights from Key West International Airport to Manchester Airport via Washington Dulles
- Ave. Duration
- 10h 24m
- When
- Every day
- Estimated price
- $110–550
Flights from Key West International Airport to Theodore Francis Green State Airport via Washington Dulles
- Ave. Duration
- 5h 23m
- When
- Every day
- Estimated price
- $85–390
Flights from Key West International Airport to Laguardia Airport via Washington Dulles
- Ave. Duration
- 5h 10m
- When
- Every day
- Estimated price
- $140–700
Flights from Key West International Airport to Newark Liberty International Airport
- Ave. Duration
- 3h 9m
- When
- Every day
- Estimated price
- $85–410
Flights from Key West International Airport to Newark Liberty International Airport via Washington Dulles
- Ave. Duration
- 5h 52m
- When
- Every day
- Estimated price
- $85–420
- Website
- jetblue.com
Flights from Key West International Airport to Worcester Regional Airport via Orlando
- Ave. Duration
- 24h 45m
- When
- Thursday, Friday, and Sunday
- Estimated price
- $110–550
Flights from Key West International Airport to Worcester Regional Airport via Miami, Orlando
- Ave. Duration
- 15h 41m
- When
- Wednesday to Sunday
- Estimated price
- $110–550
- Website
- southwest.com
Flights from Key West International Airport to Manchester Airport via Tampa
- Ave. Duration
- 7h 1m
- When
- Saturday
- Estimated price
- $110–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Miami Amtrak Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 27h 45m
- Frequency
- Once daily
- Estimated price
- $750–1,200
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Boston
- Ave. Duration
- 4h 21m
- Frequency
- Every 3 hours
- Estimated price
- $120–200
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Boston
- Ave. Duration
- 4h 21m
- Frequency
- Every 3 hours
- Estimated price
- $120–200
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Boston
- Ave. Duration
- 4h 21m
- Frequency
- Every 3 hours
- Estimated price
- $120–200
- Website
- Amtrak
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Boston
- Ave. Duration
- 3h 47m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $50–490
- First Class
- $200–750
Train from Ny Moynihan Train Hall At Penn Station to Boston
- Ave. Duration
- 3h 47m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $50–490
- First Class
- $200–750
Train from Ny Moynihan Train Hall At Penn Station to Boston
- Ave. Duration
- 3h 47m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $50–490
- First Class
- $200–750
Train from TF Green Airport to South Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $9–16
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $9–16
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Boston Manchester Airport to Boston
- Ave. Duration
- 1h 30m
- Frequency
- Twice daily
- Estimated price
- $9–14
- Website
- Greyhound
Bus from Big Pine Key to Miami Airport Station
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $23–35
- Website
- Greyhound
Bus from Newark Penn Station to Boston
- Ave. Duration
- 5h 5m
- Frequency
- 4 times a day
- Estimated price
- $45–70
- Website
- Greyhound
Bus from Worcester Union Station to Boston
- Ave. Duration
- 45 min
- Frequency
- Every 4 hours
- Estimated price
- $7–11
- Website
- Greyhound
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30
- Ave. Duration
- 54 min
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- Key West Transit
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Miami Airport Station to Newark Penn Station
- Ave. Duration
- 25h 35m
- Frequency
- 4 times a week
- Estimated price
- $210–310
- Schedules at
- Flixbus USA
Bus from Newark Penn Station to Boston
- Ave. Duration
- 4h 30m
- Frequency
- 3 times a day
- Estimated price
- $40–65
- Schedules at
- Flixbus USA
Bus from Worcester Union Station to Boston
- Ave. Duration
- 55 min
- Frequency
- 5 times a week
- Estimated price
- $6–10
- Schedules at
- Flixbus USA
- Phone
- +1 (305) 289-9997
- [email protected]
- Website
- Keys Shuttle
Shuttle from Key West, FL to Miami, FL - International Airport
- Ave. Duration
- 4h
- Frequency
- 3 times a day
- Estimated price
- $170–200
- Website
- Keys Shuttle
- Phone
- 1-800-343-9999
- Website
- Peter Pan
Bus from Worcester Union Station to Boston
- Ave. Duration
- 1h 15m
- Frequency
- Every 4 hours
- Estimated price
- $8–14
- Website
- Peter Pan
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
Booking & Getting There
There are 1794+ hotels available in Boston.
















