Rome2Rio

How to get fromKey West to Charleston Amtrak Stationby plane, bus, train, or car

Find Transport to Charleston Amtrak Station

See all options

There are 5 ways to get from Key West to Charleston Amtrak Station by plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Charleston International Airport

    best
    1. Fly from Key West International Airport (EYW) to Charleston International Airport (CHS)plane plane EYW - CHS
    5h 43m
    $286–518

  2. Drive 741.5 mi

    cheapest
    1. Drive from Key West to Charleston Amtrak Stationcar car 741.5 mi
    13h 14m
    $136–196

  3. Bus, train

    1. Take the bus from N Roosevelt & 4th Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the train from Hollywood Amtrak Station to Charleston Amtrak Stationtrain train
    20h 30m
    $224–480

  4. Fly to Savannah, train

    1. Fly from Key West International Airport (EYW) to Savannah (SAV)plane plane EYW - SAV
    2. Take the train from Savannah Station to Charleston Amtrak Stationtrain train
    6h 45m
    $442–784

  5. Fly to Myrtle Beach, bus

    1. Fly from Key West International Airport (EYW) to Myrtle Beach (MYR)plane plane EYW - MYR
    2. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    8h 33m
    $388–657

Key West to Charleston Amtrak Station by bus, foot, and train

Calendar7Weekly Services
Duration20h 30mAverage Duration
Ticket$224Cheapest Price
See schedules

Questions & Answers

Map of how to get from Key West to Charleston Amtrak Station.ExpandLaunch map view
  • Distance: 592.6 mi
  • Duration: 5h 43m

What companies run services between Key West, FL, USA and Charleston Amtrak Station, SC, USA?

American Airlines, Delta, and United Airlines fly from Key West International Airport (EYW) to Charleston International Airport (CHS) every 4 hours.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound