What is the cheapest way to get from Key West to Charleston?

The cheapest way to get from Key West to Charleston is to drive which costs $130 - $200 and takes 13h 15m.

What is the fastest way to get from Key West to Charleston?

The fastest way to get from Key West to Charleston is to fly which takes 5h 45m and costs $85 - $450.

How far is it from Key West to Charleston?

The distance between Key West and Charleston is 605 miles. The road distance is 745 miles.

How do I travel from Key West to Charleston without a car?

The best way to get from Key West to Charleston without a car is to bus and train which takes 20h 44m and costs $200 - $470.

How long does it take to get from Key West to Charleston?

It takes approximately 5h 45m to get from Key West to Charleston, including transfers.

Can I drive from Key West to Charleston?

Yes, the driving distance between Key West to Charleston is 745 miles. It takes approximately 13h 15m to drive from Key West to Charleston.

Where can I stay near Charleston?

There are 1914+ hotels available in Charleston.

Key West to Charleston - 4 ways to travel via train, plane, bus, and car

How to get fromKey West to Charleston

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There are 4 ways to get from Key West to Charleston by plane, bus, train, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly
best
1. Fly from Key West International Airport (EYW) to Charleston International Airport (CHS)plane EYW - CHS
5h 45m
$89–446
Bus, train
1. Take the bus from N Roosevelt & 4th Street to Big Pine Key - Auto Store / NAPA MM30bus Lks
2. Take the bus from Big Pine Key to Miami Airport Stationbus
3. Take the train from Hollywood Amtrak Station to Charleston Amtrak Stationtrain
20h 44m
$205–465
Drive 740.7 mi
1. Drive from Key West to Charlestoncar 740.7 mi
13h 15m
$136–196
Shuttle, bus, train
1. Take a shuttle bus from Key West, FL to Fort Lauderdale, FL - International Airportshuttle
2. Take the bus from Fort Lauderdale Airport to West Palm Beach, FLbus
3. Take the train from West Palm Beach Amtrak Station to Charleston Amtrak Stationtrain
22h 7m
$347–595

Key West to Charleston by bus, shuttle, and train

7Weekly Services

22h 7mAverage Duration

$347Cheapest Price

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Comparing Your Travel Options

Map of how to get from Key West to Charleston.

Launch map view

Distance: 601.3 mi
Duration: 5h 45m

What companies run services between Key West, FL, USA and Charleston, SC, USA?

American Airlines, Delta, and United Airlines fly from Key West International Airport (EYW) to Charleston International Airport (CHS) every 3 hours.

Airlines

Train operators

Bus operators

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