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How to get fromKey West to Columbusby plane, bus (Greyhound, Flixbus), bus, train, or car

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There are 5 ways to get from Key West to Columbus by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to John Glenn Columbus International Airport

    best
    1. Fly from Key West International Airport (EYW) to John Glenn Columbus International Airport (CMH)plane plane EYW - CMH
    6h 3m
    $154–667

  2. Bus

    1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Columbusbus bus
    35h 52m
    $221–434

  3. Bus, train

    1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the train from Miami Amtrak Station to Pittsburgh Amtrak Stationtrain train
    4. Take the bus from Pittsburgh Intermodal Station to Columbusbus bus
    47h 26m
    $566–1,222

  4. Drive 1,303.6 mi

    1. Drive from Key West to Columbuscar car 1,303.6 mi
    22h 45m
    $238–344

  5. Fly to Covington, bus

    1. Fly from Key West International Airport (EYW) to Covington (CVG)plane plane EYW - CVG
    2. Take the bus from Cincinnati - Downtown to Columbus - Downtown - Mound Stbus bus
    7h 21m
    $155–711

Key West to Columbus by bus and foot

Calendar7Weekly Services
Duration35h 52mAverage Duration
Ticket$221Cheapest Price
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Questions & Answers

Map of how to get from Key West to Columbus.ExpandLaunch map view
  • Distance: 1,084.7 mi
  • Duration: 6h 3m

What companies run services between Key West, FL, USA and Columbus, OH, USA?

Delta, United Airlines, and American Airlines fly from Key West International Airport (EYW) to John Glenn Columbus International Airport (CMH) every 3 hours. Alternatively, you can take a bus from N Roosevelt & 3rd Street to Columbus via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, and Atlanta Bus Station in around 35h 52m.

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