What is the cheapest way to get from Key West to Des Moines?

The cheapest way to get from Key West to Des Moines is to fly which costs $130 - $550 and takes 5h 46m.

What is the fastest way to get from Key West to Des Moines?

The fastest way to get from Key West to Des Moines is to fly which takes 5h 46m and costs $130 - $550.

How far is it from Key West to Des Moines?

The distance between Key West and Des Moines is 1374 miles. The road distance is 1692.3 miles.

How do I travel from Key West to Des Moines without a car?

The best way to get from Key West to Des Moines without a car is to bus and train which takes 2 days 13h and costs $550 - $1,400.

How long does it take to get from Key West to Des Moines?

It takes approximately 5h 46m to get from Key West to Des Moines, including transfers.

What is the time difference between Key West and Des Moines?

Des Moines is 1h behind Key West. It is currently 12:37 PM in Key West and 11:37 AM in Des Moines.

Can I drive from Key West to Des Moines?

Yes, the driving distance between Key West to Des Moines is 1692 miles. It takes approximately 30h 21m to drive from Key West to Des Moines.

Where can I stay near Des Moines?

There are 251+ hotels available in Des Moines.

Key West to Des Moines - 5 ways to travel via train, plane, bus, and car

How to get fromKey West to Des Moines

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There are 5 ways to get from Key West to Des Moines by plane, bus, train, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly
best
1. Fly from Key West International Airport (EYW) to Des Moines (DSM)plane EYW - DSM
5h 46m
$130–537
Bus, train
1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus Lks
2. Take the bus from Big Pine Key to Miami Airport Stationbus
3. Take the train from Miami Amtrak Station to Chicago Union Stationtrain
4. Take the bus from Chicago Bus Station to Des Moinesbus
2d 13h
$590–1,347
Bus, train via Newark
1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus Lks
2. Take the bus from Big Pine Key to Miami Airport Stationbus
3. Take the train from Miami Amtrak Station to Newark Penn Stationtrain
4. Take the bus from Newark Penn Station to Indianapolis Union Stationbus
5. Take the bus from Indianapolis Union Station to Des Moinesbus
2d 14h
$560–1,172
Drive 1,682.5 mi
1. Drive from Key West to Des Moinescar 1,682.5 mi
30h 21m
$307–444
Shuttle, train, bus
1. Take a shuttle bus from Key West, FL to Miami, FL - International Airportshuttle
2. Take the train from Miami Amtrak Station to Chicago Union Stationtrain
3. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain
4. Take the bus from Galesburg to Des Moinesbus
2d 14h
$767–1,584

Key West to Des Moines by bus, foot, taxi, and train

7Weekly Services

2d 13hAverage Duration

$590Cheapest Price

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Comparing Your Travel Options

Map of how to get from Key West to Des Moines.

Launch map view

Distance: 1,366 mi
Duration: 5h 46m

What companies run services between Key West, FL, USA and Des Moines, IA, USA?

Delta, United Airlines, and American Airlines fly from Key West International Airport (EYW) to Des Moines (DSM) every 4 hours.

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