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How to get fromKey West to Destinby plane, bus, taxi, or car

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There are 6 ways to get from Key West to Destin by plane, bus, taxi, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Destin–Fort Walton Beach Airport

    best
    1. Fly from Key West International Airport (EYW) to Destin–Fort Walton Beach Airport (VPS)plane plane EYW - VPS
    5h 25m
    $112–429

  2. Bus, taxi via Sandy Springs

    1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta to Mobilebus bus
    5. Take the bus from Loxley to Crestviewbus bus
    6. Take the taxi from Crestview to Destintaxi taxi
    29h 30m
    $320–467

  3. Drive  745.9 mi

    1. Drive from Key West to Destincar car 745.9 mi
    14h 49m
    $137–197

  4. Fly to Pensacola International Airport, taxi

    1. Fly from Key West International Airport (EYW) to Pensacola International Airport (PNS)plane plane EYW - PNS
    2. Take the taxi from Pensacola-Airport-PNS to Destintaxi taxi
    5h 43m
    $182–464

  5. Fly to Northwest Florida Beaches International Airport, taxi

    1. Fly from Key West International Airport (EYW) to Northwest Florida Beaches International Airport (ECP)plane plane EYW - ECP
    2. Take the taxi from Northwest Florida Beaches International Airport (ECP) to Destintaxi taxi
    5h 31m
    $227–604

  6. Bus, taxi

    1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Tallahasseebus bus
    4. Take the bus from Tallahassee to Montgomery Intermodal Centerbus bus
    5. Take the bus from Montgomery Intermodal Center to Biloxi Transit Centerbus bus
    6. Take the bus from Biloxi to Crestviewbus bus
    7. Take the taxi from Crestview to Destintaxi taxi
    36h 17m
    $307–464

Key West International Airport (EYW) to Destin–Fort Walton Beach Airport (VPS) flights

Calendar47Weekly Planes
Duration6h 31mAverage Duration
Ticket$64Cheapest Price
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Comparing Your Travel Options

Map of how to get from Key West to Destin.ExpandLaunch map view
  • Distance: 523 mi
  • Duration: 5h 25m

What companies run services between Key West, FL, USA and Destin, FL, USA?

American Airlines, Delta, and Allegiant Air fly from Key West International Airport (EYW) to Destin–Fort Walton Beach Airport (VPS) every 4 hours.

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