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How to get fromKey West to Florida Panhandleby plane, car, shuttle, bus, or train

Find Transport to Florida Panhandle

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There are 9 ways to get from Key West to Florida Panhandle by plane, car, shuttle, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Tallahassee, drive

    best
    1. Fly from Key West International Airport (EYW) to Tallahassee (TLH)plane plane EYW - TLH
    2. Drive from Tallahassee (TLH) to Florida Panhandlecar car
    5h 29m
    $97–479

  2. Fly to Destin–Fort Walton Beach Airport, drive

    cheapest
    1. Fly from Key West International Airport (EYW) to Destin–Fort Walton Beach Airport (VPS)plane plane EYW - VPS
    2. Drive from Destin–Fort Walton Beach Airport (VPS) to Florida Panhandlecar car
    7h 10m
    $90–401

  3. Shuttle, bus, drive

    1. Take a shuttle bus from Key West, FL to Miami, FL - International Airportshuttle bus
    2. Take the bus from Miami Airport to Tallahassee - FSU - Old St Augustine at Intramural Fieldbus bus
    3. Drive from Tallahassee - FSU - Old St Augustine at Intramural Field to Florida Panhandlecar car
    16h 36m
    $302–389

  4. Drive  660 mi

    1. Drive from Key West to Florida Panhandlecar car 660 mi
    13h 9m
    $121–174

  5. Fly to Northwest Florida Beaches International Airport, drive

    1. Fly from Key West International Airport (EYW) to Northwest Florida Beaches International Airport (ECP)plane plane EYW - ECP
    2. Drive from Northwest Florida Beaches International Airport (ECP) to Florida Panhandlecar car
    5h 48m
    $97–439

  6. Fly to Dothan Regional Airport, drive

    1. Fly from Key West International Airport (EYW) to Dothan Regional Airport (DHN)plane plane EYW - DHN
    2. Drive from Dothan Regional Airport (DHN) to Florida Panhandlecar car
    6h 44m
    $101–436

  7. Bus, drive

    1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport to Tallahassee - FSU - Old St Augustine at Intramural Fieldbus bus
    4. Drive from Tallahassee - FSU - Old St Augustine at Intramural Field to Florida Panhandlecar car
    17h 7m
    $152–224

  8. Bus, train, drive

    1. Take the bus from N Roosevelt & 4th Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the train from Miami to Orlandotrain train
    4. Take the bus from Orlando - RedCoach Station, FL to Tallahassee - FSU - Old St Augustine at Intramural Fieldbus bus
    5. Drive from Tallahassee - FSU - Old St Augustine at Intramural Field to Florida Panhandlecar car
    17h 57m
    $160–341

  9. Bus, drive via Tallahassee

    1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Tallahasseebus bus
    4. Drive from Capital Circle NW and Commonwealth Boulevard to Florida Panhandlecar car
    22h 45m
    $119–196

Key West International Airport (EYW) to Tallahassee (TLH) flights

Calendar62Weekly Planes
Duration5h 35mAverage Duration
Ticket$76Cheapest Price
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Comparing Your Travel Options

Map of how to get from Key West to Florida Panhandle.ExpandLaunch map view
  • Distance: 492.4 mi
  • Duration: 5h 29m

What companies run services between Key West, FL, USA and Florida Panhandle, FL, USA?

There is no direct connection from Key West to Florida Panhandle. However, you can take the taxi to Key West International Airport (EYW) airport, fly to Tallahassee (TLH), then drive to Florida Panhandle. Alternatively, you can take a bus from Palm Ave & Charter Row to Florida Panhandle via Whitehead & Eaton, Key West, FL, Miami, FL - International Airport, Miami Airport, and Tallahassee - FSU - Old St Augustine at Intramural Field in around 16h 36m.

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