Rome2Rio

How to get fromKey West to Gainesvilleby plane, bus, train, car, bus (Greyhound, Flixbus), or ferry

Find Transport to Gainesville

See all options

There are 8 ways to get from Key West to Gainesville by plane, bus, train, car, bus (Greyhound, Flixbus), or ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Gainesville Regional Airport

    best
    1. Fly from Key West International Airport (EYW) to Gainesville Regional Airport (GNV)plane plane EYW - GNV
    5h 32m
    $64–346

  2. Bus, train

    1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the train from Miami Airport Station to West Palm Beach Stationtrain train
    4. Take the bus from West Palm Beach, FL to University of Florida - 1956 Gale Lemerand Drbus bus
    13h 54m
    $96–195

  3. Drive 474.6 mi

    1. Drive from Key West to Gainesvillecar car 474.6 mi
    9h 22m
    $87–126

  4. Fly to Orlando, bus

    1. Fly from Key West International Airport (EYW) to Orlando (MCO)plane plane EYW - MCO
    2. Take the bus from Orlando - RedCoach Station, FL to University of Florida - 1956 Gale Lemerand Drbus bus
    5h 3m
    $113–721

  5. Fly to Jacksonville, bus

    1. Fly from Key West International Airport (EYW) to Jacksonville (JAX)plane plane EYW - JAX
    2. Take the bus from Jacksonville to Gainesvillebus bus
    8h 21m
    $383–834

  6. Bus

    1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Gainesvillebus bus
    14h 7m
    $71–129

  7. Ferry, bus

    1. Take the ferry from Key West, FL to Fort Myers Beach, FLferry ferry
    2. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    3. Take the bus from Tampa Bus Station to Gainesvillebus bus
    14h 48m
    $172–209

  8. Bus, train via Tampa

    1. Take the bus from N Roosevelt & 4th Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the train from Hollywood Amtrak Station to Tampatrain train
    4. Take the bus from Tampa Bus Station to Gainesvillebus bus
    16h 4m
    $117–249

Key West to Gainesville by bus, foot, and train

Calendar19Weekly Services
Duration13h 54mAverage Duration
Ticket$96Cheapest Price
See schedules

Questions & Answers

Map of how to get from Key West to Gainesville.ExpandLaunch map view
  • Distance: 365.5 mi
  • Duration: 5h 32m

What companies run services between Key West, FL, USA and Gainesville, FL, USA?

American Airlines and Delta fly from Key West International Airport (EYW) to Gainesville Regional Airport (GNV) 5 times a day. Alternatively, you can take a bus from N Roosevelt & 3rd Street to Gainesville via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, and Miami Airport Station in around 14h 7m.

Airlines
Train operators
Bus operators
Ferry operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers