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How to get fromKey West to Great Smoky Mountainsby plane, car, shuttle, bus, or train

Find Transport to Great Smoky Mountains

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There are 9 ways to get from Key West to Great Smoky Mountains by plane, car, shuttle, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Mcghee Tyson Airport, drive

    best
    1. Fly from Key West International Airport (EYW) to Mcghee Tyson Airport (TYS)plane plane EYW - TYS
    2. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    4h 12m
    $152–730

  2. Fly to Asheville Regional Airport, drive

    cheapest
    1. Fly from Key West International Airport (EYW) to Asheville Regional Airport (AVL)plane plane EYW - AVL
    2. Drive from Asheville-Airport-AVL to Great Smoky Mountainscar car
    4h 16m
    $96–406

  3. Shuttle, bus, drive

    1. Take a shuttle bus from Key West, FL to Miami, FL - International Airportshuttle bus
    2. Take the bus from Miami to Fayetteville Bus Stationbus bus
    3. Take the bus from Fayetteville to Winston-Salembus bus
    4. Take the bus from Winston Salem(Trans Center) to Asheville, NCbus bus
    5. Drive from New Leicester Hwy at Walgreens to Great Smoky Mountainscar car
    33h 11m
    $368–556

  4. Bus, train, drive

    1. Take the bus from N Roosevelt & 4th Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the train from Hollywood Amtrak Station to Carytrain train
    4. Take the train from Cary to Greensborotrain train
    5. Take the bus from Greensboro Bus Stop to Asheville, NCbus bus
    6. Drive from Asheville, NC to Great Smoky Mountainscar car
    37h 9m
    $396–820

  5. Drive 948.9 mi

    1. Drive from Key West to Great Smoky Mountainscar car 948.9 mi
    19h 16m
    $174–251

  6. Fly to Greenville–Spartanburg International Airport, drive

    1. Fly from Key West International Airport (EYW) to Greenville–Spartanburg International Airport (GSP)plane plane EYW - GSP
    2. Drive from Greenville–Spartanburg International Airport (GSP) to Great Smoky Mountainscar car
    7h 9m
    $146–599

  7. Fly to Hartsfield-Jackson Atlanta International Airport, drive

    1. Fly from Key West International Airport (EYW) to Hartsfield-Jackson Atlanta International Airport (ATL)plane plane EYW - ATL
    2. Drive from Atlanta-Airport-ATL to Great Smoky Mountainscar car
    6h 19m
    $132–529

  8. Fly to Chattanooga Metropolitan Airport, drive

    1. Fly from Key West International Airport (EYW) to Chattanooga Metropolitan Airport (CHA)plane plane EYW - CHA
    2. Drive from Chattanooga Metropolitan Airport (CHA) to Great Smoky Mountainscar car
    8h 5m
    $179–804

  9. Bus, drive

    1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Ft Lauderdale Broward Park & Ridebus bus
    4. Take the bus from Ft Lauderdale Broward Park & Ride to Fayetteville Bus Stationbus bus
    5. Take the bus from Fayetteville Bus Station to Raleigh Bus Stationbus bus
    6. Take the bus from Raleigh Bus Station to Asheville, NCbus bus
    7. Drive from Asheville, NC to Great Smoky Mountainscar car
    33h 16m
    $202–377

Key West International Airport (EYW) to Mcghee Tyson Airport (TYS) flights

Calendar30Weekly Planes
Duration4h 41mAverage Duration
Ticket$135Cheapest Price
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Questions & Answers

Map of how to get from Key West to Great Smoky Mountains.ExpandLaunch map view
  • Distance: 850.2 mi
  • Duration: 4h 12m

What companies run services between Key West, FL, USA and Great Smoky Mountains, TN, USA?

There is no direct connection from Key West to Great Smoky Mountains. However, you can take the taxi to Key West International Airport (EYW) airport, fly to Mcghee Tyson Airport (TYS), then drive to Great Smoky Mountains. Alternatively, you can take a bus from Palm Ave & Charter Row to Great Smoky Mountains via Whitehead & Eaton, Key West, FL, Miami, FL - International Airport, Miami, Fayetteville Bus Station, Fayetteville, Winston Salem(Trans Center), Asheville, NC, ART Station, and New Leicester Hwy at Walgreens in around 33h 11m.

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