There are 2 ways to get from Key West to Guantánamo by plane or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Antonio Maceo International Airport, bus
best- Fly from Key West International Airport (EYW) to Antonio Maceo International Airport (SCU)plane EYW - SCU
- Take the bus from Santiago de Cuba to Guantanamobus
12h 23m$101–487Fly to Frank País International Airport, bus
- Fly from Key West International Airport (EYW) to Frank País International Airport (HOG)plane EYW - HOG
- Take the bus from Holguin Airport to Terminal de Ómnibus Nacionales Santiago de Cubabus
- Take the bus from Santiago de Cuba to Guantanamobus
9h 57m$113–506
Key West International Airport (EYW) to Antonio Maceo International Airport (SCU) flights
Comparing Your Travel Options
The cheapest way to get from Key West to Guantánamo is to fly and bus which costs $100 - $490 and takes 12h 23m.
The fastest way to get from Key West to Guantánamo is to fly and bus which takes 9h 57m and costs $110 - $550.
The distance between Key West and Guantánamo is 884 km.
It takes approximately 12h 23m to get from Key West to Guantánamo, including transfers.
What companies run services between Key West, FL, USA and Guantánamo, Cuba?
There is no direct connection from Key West to Guantánamo. However, you can take the taxi to Key West International Airport (EYW) airport, fly to Antonio Maceo International Airport (SCU), walk to Santiago Airport, take the bus to La Colonia, walk to Santiago de Cuba, then take the bus to Guantanamo. Alternatively, you can take the taxi to Key West International Airport (EYW) airport, fly to Frank País International Airport (HOG), walk to Holguin Airport, take the bus to Terminal de Ómnibus Nacionales Santiago de Cuba, walk to Mercado Ferrocarriles, take the bus to Ferrocaribe, walk to Santiago de Cuba, then take the bus to Guantanamo.
- Website
- aa.com
Flights from Key West International Airport to Antonio Maceo International Airport via Miami
- Ave. Duration
- 15h 29m
- When
- Wednesday to Sunday
- Estimated price
- $70–410
Flights from Key West International Airport to Frank País International Airport via Miami
- Ave. Duration
- 3h 36m
- When
- Every day
- Estimated price
- $70–410
- Website
- intercaribbean.com
Flights from Key West International Airport to Antonio Maceo International Airport via Miami, Kingston
- Ave. Duration
- 9h 21m
- When
- Wednesday
- Estimated price
- $90–460
- Phone
- +(537) 206 9590
- [email protected]
- Website
- ecured.cu
Bus from Santiago de Cuba to Guantanamo
- Ave. Duration
- 1h
- Frequency
- Once a week
- Estimated price
- $16–60
- Schedules at
- viajescubanacan.cu
Bus from Santiago de Cuba to Guantanamo
- Ave. Duration
- 1h
- Frequency
- Once a week
- Estimated price
- $16–60
- Schedules at
- viajescubanacan.cu
- Phone
- +53 59 89 0616
- [email protected]
- Website
- Viazul
Bus from Holguin Airport to Terminal de Ómnibus Nacionales Santiago de Cuba
- Ave. Duration
- 2h 47m
- Frequency
- 5 times a day
- Estimated price
- $15–22
- Website
- Viazul
Want to know more about travelling around the world?
Rome2Rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including How to get from Luton Airport into central London, Slovenia: Getting from Ljubljana to Lake Bled, and How to get from London City Airport into central London - to help you get the most out of your next trip.







