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How to get fromKey West to Jacksonvilleby plane, bus (Greyhound, Flixbus), bus, train, car, or shuttle

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There are 5 ways to get from Key West to Jacksonville by plane, bus (Greyhound, Flixbus), bus, train, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Key West International Airport (EYW) to Jacksonville (JAX)plane plane EYW - JAX
    5h 52m
    $373–817

  2. Bus

    cheapest
    1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Jacksonvillebus bus
    15h 42m
    $81–164

  3. Bus, train

    1. Take the bus from N Roosevelt & 4th Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the train from Hollywood Amtrak Station to Jacksonvilletrain train
    16h 46m
    $145–313

  4. Drive 502.8 mi

    1. Drive from Key West to Jacksonvillecar car 502.8 mi
    9h 8m
    $92–133

  5. Shuttle, bus

    1. Take a shuttle bus from Plaza Hotel to Bayside Marketplaceshuttle bus
    2. Take the bus from Miami Golden Glades to Jacksonvillebus bus FlixBus 2431
    16h 11m
    $125–167

Key West to Jacksonville by bus and foot

Calendar18Weekly Services
Duration15h 42mAverage Duration
Ticket$81Cheapest Price
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Questions & Answers

Map of how to get from Key West to Jacksonville.ExpandLaunch map view
  • Distance: 430.3 mi
  • Duration: 5h 52m

What companies run services between Key West, FL, USA and Jacksonville, FL, USA?

Delta and American Airlines fly from Key West International Airport (EYW) to Jacksonville (JAX) every 4 hours. Alternatively, you can take a bus from N Roosevelt & 3rd Street to Jacksonville via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, and Miami Airport Station in around 15h 42m.

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