There are 7 ways to get from Key West to Louisville by plane, bus (Greyhound, Flixbus), car, bus, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Louisville International Airport
best- Fly from Key West International Airport (EYW) to Louisville International Airport (SDF)plane EYW - SDF
5h 43m$153–767Fly to Blue Grass Airport, drive
cheapest- Fly from Key West International Airport (EYW) to Blue Grass Airport (LEX)plane EYW - LEX
- Drive from Lexington-Airport-LEX to Louisvillecar
5h 16m$105–453Bus
- Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus Lks
- Take the bus from Big Pine Key to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Louisville Bus Stationbus
30h 2m$182–319Drive 1,174.7 mi
- Drive from Key West to Louisvillecar 1,174.7 mi
22h 8m$215–310Fly to Covington, bus
- Fly from Key West International Airport (EYW) to Covington (CVG)plane EYW - CVG
- Take the bus from Cincinnati to Louisvillebus
6h 33m$163–811Fly to Evansville, bus
- Fly from Key West International Airport (EYW) to Evansville (EVV)plane EYW - EVV
- Take the bus from Evansville, IN to Louisville, KYbus
8h 37m$152–599Bus via Tallahassee
- Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus Lks
- Take the bus from Big Pine Key to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Tallahasseebus
- Take the bus from Tallahassee to Montgomery Intermodal Centerbus
- Take the bus from Montgomery Intermodal Center to Louisville Bus Stationbus
37h 52m$212–359
Key West to Louisville by bus and foot
Comparing Your Travel Options
The cheapest way to get from Key West to Louisville is to bus which costs $180 - $320 and takes 30h 2m.
The fastest way to get from Key West to Louisville is to fly and drive which takes 5h 16m and costs $100 - $460.
No, there is no direct bus from Key West to Louisville station. However, there are services departing from N Roosevelt & 3rd Street and arriving at Louisville Bus Station via Big Pine Key, Miami Airport Station and Atlanta Bus Station. The journey, including transfers, takes approximately 30h 2m.
The distance between Key West and Louisville is 985 miles. The road distance is 1181.5 miles.
The best way to get from Key West to Louisville without a car is to bus which takes 30h 2m and costs $180 - $320.
It takes approximately 5h 43m to get from Key West to Louisville, including transfers.
Key West to Louisville bus services, operated by Key West Transit, depart from N Roosevelt & 3rd Street station.
The best way to get from Key West to Louisville is to fly which takes 5h 43m and costs $150 - $800. Alternatively, you can bus, which costs $180 - $320 and takes 30h 2m.
Key West to Louisville bus services, operated by Key West Transit, arrive at Big Pine Key - Auto Store / NAPA MM30 station.
Yes, the driving distance between Key West to Louisville is 1182 miles. It takes approximately 22h 8m to drive from Key West to Louisville.
What companies run services between Key West, FL, USA and Louisville, KY, USA?
Delta, American Airlines, and Breeze Airways fly from Key West International Airport (EYW) to Louisville International Airport (SDF) every 4 hours. Alternatively, you can take a bus from N Roosevelt & 3rd Street to Louisville Bus Station via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, and Atlanta Bus Station in around 30h 2m.
- Website
- delta.com
Flights from Key West International Airport to Louisville International Airport via Atlanta
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- $140–750
Flights from Key West International Airport to Blue Grass Airport via Atlanta
- Ave. Duration
- 5h 19m
- When
- Every day
- Estimated price
- $80–420
Flights from Key West International Airport to Covington via Atlanta
- Ave. Duration
- 5h 26m
- When
- Every day
- Estimated price
- $140–750
Flights from Key West International Airport to Evansville via Atlanta
- Ave. Duration
- 6h 1m
- When
- Every day
- Estimated price
- $85–430
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30
- Ave. Duration
- 54 min
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- Key West Transit
Bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30
- Ave. Duration
- 54 min
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- Key West Transit
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Booking & Getting There
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