There are 6 ways to get from Key West to Louisville by plane, bus (Greyhound, Flixbus, Amtrak), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Louisville International Airport
best- Fly from Key West International Airport (EYW) to Louisville International Airport (SDF)plane EYW - SDF
5h 58m$123–567Bus
- Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus Lks
- Take the bus from Big Pine Key to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Nashville Bus Stationbus
- Take the bus from Nashville to Louisville, KYbus
29h 32m$187–369Drive 1,176 mi
- Drive from Key West to Louisvillecar 1,176 mi
22h 7m$215–310Fly to Blue Grass Airport, drive
- Fly from Key West International Airport (EYW) to Blue Grass Airport (LEX)plane EYW - LEX
- Drive from Lexington-Airport-LEX to Louisvillecar
5h 56m$185–833Fly to Covington, bus
- Fly from Key West International Airport (EYW) to Covington (CVG)plane EYW - CVG
- Take the bus from Cincinnati - Downtown to Louisville, KY Bus Stationbus
6h 40m$143–661Fly to Evansville, bus
- Fly from Key West International Airport (EYW) to Evansville (EVV)plane EYW - EVV
- Take the bus from Evansville, IN to Louisville, KYbus
9h 55m$147–484
Key West to Louisville by bus and foot
Questions & Answers
The cheapest way to get from Key West to Louisville is to bus which costs $180 - $370 and takes 29h 32m.
The fastest way to get from Key West to Louisville is to fly and drive which takes 5h 56m and costs $180 - $850.
No, there is no direct bus from Key West to Louisville. However, there are services departing from N Roosevelt & 3rd Street and arriving at Louisville, KY via Big Pine Key, Miami Airport Station, Atlanta Bus Station and Nashville. The journey, including transfers, takes approximately 29h 32m.
The distance between Key West and Louisville is 985 miles. The road distance is 1182.9 miles.
The best way to get from Key West to Louisville without a car is to bus which takes 29h 32m and costs $180 - $370.
It takes approximately 5h 58m to get from Key West to Louisville, including transfers.
Key West to Louisville bus services, operated by Key West Transit, depart from N Roosevelt & 3rd Street station.
The best way to get from Key West to Louisville is to fly which takes 5h 58m and costs $120 - $600. Alternatively, you can bus, which costs $180 - $370 and takes 29h 32m.
Key West to Louisville bus services, operated by Key West Transit, arrive at Big Pine Key - Auto Store / NAPA MM30 station.
Yes, the driving distance between Key West to Louisville is 1183 miles. It takes approximately 22h 7m to drive from Key West to Louisville.
What companies run services between Key West, FL, USA and Louisville, KY, USA?
Delta and American Airlines fly from Key West International Airport (EYW) to Louisville International Airport (SDF) every 4 hours. Alternatively, you can take a bus from N Roosevelt & 3rd Street to Louisville, KY via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, Atlanta Bus Station, and Nashville in around 29h 32m.
- Website
- aa.com
Flights from Key West International Airport to Louisville International Airport via Miami
- Ave. Duration
- 6h 52m
- When
- Tuesday, Saturday, and Wednesday
- Estimated price
- $110–550
Flights from Key West International Airport to Louisville International Airport via Charlotte
- Ave. Duration
- 7h 3m
- When
- Every day
- Estimated price
- $110–550
Flights from Key West International Airport to Blue Grass Airport via Charlotte
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- $170–850
Flights from Key West International Airport to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 6h 50m
- When
- Every day
- Estimated price
- $240–1,100
Flights from Key West International Airport to Blue Grass Airport via Philadelphia
- Ave. Duration
- 9h 27m
- When
- Every day
- Estimated price
- $240–1,100
Flights from Key West International Airport to Covington via Charlotte
- Ave. Duration
- 5h 54m
- When
- Every day
- Estimated price
- $130–600
Flights from Key West International Airport to Covington via Miami
- Ave. Duration
- 5h 36m
- When
- Wednesday to Sunday
- Estimated price
- $130–600
Flights from Key West International Airport to Evansville via Charlotte
- Ave. Duration
- 7h 25m
- When
- Every day
- Estimated price
- $90–420
Flights from Key West International Airport to Evansville via Chicago O'Hare
- Ave. Duration
- 8h 31m
- When
- Every day
- Estimated price
- $110–490
Flights from Key West International Airport to Evansville via Dallas/Ft.Worth
- Ave. Duration
- 10h 6m
- When
- Every day
- Estimated price
- $120–550
- Website
- delta.com
Flights from Key West International Airport to Louisville International Airport via Atlanta
- Ave. Duration
- 5h 20m
- When
- Every day
- Estimated price
- $110–550
Flights from Key West International Airport to Blue Grass Airport via Atlanta
- Ave. Duration
- 4h 54m
- When
- Every day
- Estimated price
- $160–800
Flights from Key West International Airport to Covington via Atlanta
- Ave. Duration
- 5h 9m
- When
- Every day
- Estimated price
- $120–600
Flights from Key West International Airport to Evansville via Atlanta
- Ave. Duration
- 7h 6m
- When
- Every day
- Estimated price
- $80–390
- Website
- allegiantair.com
Flights from Key West International Airport to Covington
- Ave. Duration
- 2h 43m
- When
- Monday and Friday
- Estimated price
- $120–600
Flights from Key West International Airport to Covington via St. Petersburg
- Ave. Duration
- 4h 17m
- When
- Thursday, Monday, and Friday
- Estimated price
- $120–600
- Website
- united.com
Flights from Key West International Airport to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 7h 55m
- When
- Every day
- Estimated price
- $240–1,100
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30
- Ave. Duration
- 54 min
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Big Pine Key to Miami Airport Station
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $20–40
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Atlanta Bus Station
- Ave. Duration
- 16h
- Frequency
- Once daily
- Estimated price
- $100–200
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Nashville Bus Station
- Ave. Duration
- 4h 15m
- Frequency
- Every 4 hours
- Estimated price
- $35–75
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Miami Airport Station to Atlanta Bus Station
- Ave. Duration
- 13h 5m
- Frequency
- Once daily
- Estimated price
- $100–180
- Schedules at
- flixbus.com
Bus from Atlanta Bus Station to Nashville Bus Station
- Ave. Duration
- 4h 35m
- Frequency
- Twice daily
- Estimated price
- $35–65
- Schedules at
- flixbus.com
Rome2Rio's guide to Amtrak Thruway
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Nashville to Louisville, KY
- Ave. Duration
- 3h 40m
- Frequency
- Twice daily
- Estimated price
- $30–50
- Website
- https://www.amtrak.com/home.html
- Adult
- $30–50
- Phone
- +1 888-378-3823
- [email protected]
- Website
- baronsbus.com
Bus from Cincinnati - Downtown to Louisville, KY Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $9–45
- Website
- https://baronsbus.com
- Phone
- +1 502-368-5644 x 135
- Website
- ridewithmiller.com
Bus from Evansville, IN to Louisville, KY
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $35–55
- Website
- https://ridewithmiller.com
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