There are 2 ways to get from Key West to Maine by bus, train, or bus (Greyhound, Flixbus, Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, train
best- Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus Lks
- Take the bus from Big Pine Key to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Newark Penn Stationbus
- Take the train from Newark Penn Station to Bostontrain
- Take the bus from Boston, MA - South Station to Portland, MEbus
39h 51m$365–588Bus
cheapest- Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus Lks
- Take the bus from Big Pine Key to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Washington Union Stationbus
- Take the bus from Washington Union Station to Bostonbus
- Take the bus from Boston, MA - South Station to Portland, MEbus
41h 14m$265–438
Key West to Maine by bus, foot, and train
Comparing Your Travel Options
The cheapest way to get from Key West to Maine is to bus which costs $260 - $440 and takes 41h 14m.
The fastest way to get from Key West to Maine is to bus and train which takes 39h 51m and costs $360 - $600.
No, there is no direct bus from Key West to Maine. However, there are services departing from N Roosevelt & 3rd Street and arriving at Congress St + Center St via Big Pine Key, Miami Airport Station, Washington Union Station, Boston, MA - South Station and Ptc. The journey, including transfers, takes approximately 41h 14m.
The distance between Key West and Maine is 1705 miles.
The best way to get from Key West to Maine without a car is to bus and train which takes 39h 51m and costs $360 - $600.
It takes approximately 39h 51m to get from Key West to Maine, including transfers.
Key West to Maine bus services, operated by Key West Transit, depart from N Roosevelt & 3rd Street station.
Key West to Maine bus services, operated by Key West Transit, arrive at Big Pine Key - Auto Store / NAPA MM30 station.
There are 391+ hotels available in Maine.
What companies run services between Key West, FL, USA and Maine, USA?
You can take a bus from N Roosevelt & 3rd Street to Congress St + Center St via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, Washington Union Station, Boston, Boston, MA - South Station, and Ptc in around 41h 14m.
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Newark Penn Station to Boston
- Ave. Duration
- 4h 14m
- Frequency
- Every 4 hours
- Estimated price
- $55–750
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $55–490
- First Class
- $210–750
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Newark Penn Station to Boston
- Ave. Duration
- 5h 17m
- Frequency
- Every 3 hours
- Estimated price
- $130–210
- Website
- Amtrak
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30
- Ave. Duration
- 54 min
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- Key West Transit
Bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30
- Ave. Duration
- 54 min
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- Key West Transit
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Big Pine Key to Miami Airport Station
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $20–35
- Website
- Greyhound
Bus from Big Pine Key to Miami Airport Station
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $20–35
- Website
- Greyhound
Bus from Washington Union Station to Boston
- Ave. Duration
- 9h 45m
- Frequency
- Once daily
- Estimated price
- $70–110
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Miami Airport Station to Newark Penn Station
- Ave. Duration
- 25h 35m
- Frequency
- 4 times a week
- Estimated price
- $190–290
- Schedules at
- Flixbus USA
Bus from Miami Airport Station to Washington Union Station
- Ave. Duration
- 21h 35m
- Frequency
- 4 times a week
- Estimated price
- $160–240
- Schedules at
- Flixbus USA
Bus from Washington Union Station to Boston
- Ave. Duration
- 9h 25m
- Frequency
- Twice daily
- Estimated price
- $60–95
- Schedules at
- Flixbus USA
- Phone
- +1 800 639 3317
- [email protected]
- Website
- Concord Coach Lines
Bus from Boston, MA - South Station to Portland, ME
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- $23–35
- Website
- Concord Coach Lines
Bus from Boston, MA - South Station to Portland, ME
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- $23–35
- Website
- Concord Coach Lines
Rome2Rio's guide to Amtrak Thruway
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Boston, MA - South Station to Portland, ME
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- $21–45
- Website
- Amtrak
- Adult
- $21–45
Bus from Boston, MA - South Station to Portland, ME
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- $21–45
- Website
- Amtrak
- Adult
- $21–45
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