There are 7 ways to get from Key West to Mississippi by plane, bus (Greyhound, Flixbus), car, shuttle, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Memphis
best- Fly from Key West International Airport (EYW) to Memphis (MEM)plane EYW - MEM
4h 40m$184–841Fly to Golden Triangle Regional Airport, drive
cheapest- Fly from Key West International Airport (EYW) to Golden Triangle Regional Airport (GTR)plane EYW - GTR
- Drive from Golden Triangle Regional Airport (GTR) to Tupelocar
5h 49m$98–441Bus
- Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus Lks
- Take the bus from Big Pine Key to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Jacksonbus
28h 32m$182–304Drive 1,043.8 mi
- Drive from Key West to Jacksoncar 1,043.8 mi
18h 53m$191–276Fly to Gulfport-Biloxi Regional Airport
- Fly from Key West International Airport (EYW) to Gulfport-Biloxi Regional Airport (GPT)plane EYW - GPT
5h 18m$118–518Fly to Jackson/Vicksburg
- Fly from Key West International Airport (EYW) to Jackson/Vicksburg (JAN)plane EYW - JAN
4h 50m$127–474Shuttle, bus
- Take a shuttle bus from Key West, FL to Miami, FL - International Airport
- Take the bus from Miami Airport to Tallahassee - FSU - Old St Augustine at Intramural Fieldbus
- Take the bus from Tallahassee to Baton Rouge Bus Stationbus
- Take the bus from Baton Rouge Bus Station to Jacksonbus
34h 1m$404–566
Key West to Mississippi by bus and foot
Comparing Your Travel Options
The cheapest way to get from Key West to Mississippi is to bus which costs $180 - $310 and takes 28h 32m.
The fastest way to get from Key West to Mississippi is to fly which takes 4h 40m and costs $180 - $850.
No, there is no direct bus from Key West to Mississippi. However, there are services departing from N Roosevelt & 3rd Street and arriving at Jackson via Big Pine Key, Miami Airport Station and Atlanta Bus Station. The journey, including transfers, takes approximately 28h 32m.
The distance between Key West and Mississippi is 890 miles. The road distance is 1049.9 miles.
The best way to get from Key West to Mississippi without a car is to bus which takes 28h 32m and costs $180 - $310.
It takes approximately 4h 40m to get from Key West to Mississippi, including transfers.
Key West to Mississippi bus services, operated by Key West Transit, depart from N Roosevelt & 3rd Street station.
The best way to get from Key West to Mississippi is to fly which takes 4h 40m and costs $180 - $850. Alternatively, you can bus, which costs $180 - $310 and takes 28h 32m.
Key West to Mississippi bus services, operated by Key West Transit, arrive at Big Pine Key - Auto Store / NAPA MM30 station.
Mississippi is 1h behind Key West. It is currently 3:39 AM in Key West and 2:39 AM in Mississippi.
What companies run services between Key West, FL, USA and Mississippi, USA?
Allegiant Air, Delta, and two other airlines fly from Key West International Airport (EYW) to Memphis (MEM) every 3 hours. Alternatively, you can take a bus from N Roosevelt & 3rd Street to Jackson via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, and Atlanta Bus Station in around 28h 32m.
- Website
- delta.com
Flights from Key West International Airport to Memphis via Atlanta
- Ave. Duration
- 4h 50m
- When
- Every day
- Estimated price
- $160–800
Flights from Key West International Airport to Gulfport-Biloxi Regional Airport via Atlanta
- Ave. Duration
- 6h 56m
- When
- Every day
- Estimated price
- $95–490
Flights from Key West International Airport to Jackson/Vicksburg via Atlanta
- Ave. Duration
- 5h 20m
- When
- Every day
- Estimated price
- $85–430
Flights from Key West International Airport to Golden Triangle Regional Airport via Atlanta
- Ave. Duration
- 6h 50m
- When
- Every day
- Estimated price
- $75–410
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30
- Ave. Duration
- 54 min
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- Key West Transit
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Booking & Getting There
Yes, the driving distance between Key West to Mississippi is 1050 miles. It takes approximately 18h 53m to drive from Key West to Mississippi.
There are 221+ hotels available in Mississippi.