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How to get fromKey West to New Orleansby plane, shuttle, bus, car, train, or bus (Greyhound, Flixbus)

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There are 5 ways to get from Key West to New Orleans by plane, shuttle, bus, car, train, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Louis Armstrong New Orleans International Airport

    best
    1. Fly from Key West International Airport (EYW) to Louis Armstrong New Orleans International Airport (MSY)plane plane EYW - MSY
    5h 9m
    $453–867

  2. Fly to Gulfport-Biloxi Regional Airport, train

    cheapest
    1. Fly from Key West International Airport (EYW) to Gulfport-Biloxi Regional Airport (GPT)plane plane EYW - GPT
    2. Take the train from Gulfport, MS to New Orleans, LA - Union Passenger Terminaltrain train
    9h 8m
    $150–550

  3. Shuttle, bus

    1. Take a shuttle bus from Key West, FL to Miami, FL - International Airportshuttle bus
    2. Take the bus from Miami Airport to Tallahassee - FSU - Old St Augustine at Intramural Fieldbus bus
    3. Take the bus from Tallahassee to Mobile Bus Stationbus bus
    4. Take the bus from Mobile Bus Station to New Orleans Bus Stationbus bus
    26h 51m
    $356–571

  4. Drive 1,001.6 mi

    1. Drive from Key West to New Orleanscar car 1,001.6 mi
    17h 49m
    $183–264

  5. Bus

    1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Tallahasseebus bus
    4. Take the bus from Tallahassee to Mobile Bus Stationbus bus
    5. Take the bus from Mobile Bus Station to New Orleans Bus Stationbus bus
    31h 12m
    $169–339

Key West to New Orleans by bus and foot

Calendar12Weekly Services
Duration31h 12mAverage Duration
Ticket$169Cheapest Price
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Questions & Answers

Map of how to get from Key West to New Orleans.ExpandLaunch map view
  • Distance: 657.2 mi
  • Duration: 5h 9m

What companies run services between Key West, FL, USA and New Orleans, LA, USA?

American Airlines, Delta, and Breeze Airways fly from Key West International Airport (EYW) to Louis Armstrong New Orleans International Airport (MSY) every 4 hours. Alternatively, you can take a bus from N Roosevelt & 3rd Street to New Orleans Bus Station via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, Tallahassee, and Mobile Bus Station in around 31h 12m.

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