What is the cheapest way to get from Key West to Port Saint Lucie?

The cheapest way to get from Key West to Port Saint Lucie is to drive which costs $45 - $75 and takes 5h 23m.

What is the fastest way to get from Key West to Port Saint Lucie?

The fastest way to get from Key West to Port Saint Lucie is to fly and drive which takes 3h 49m and costs $75 - $320.

Is there a direct bus between Key West and Port Saint Lucie?

No, there is no direct bus from Key West to Port Saint Lucie. However, there are services departing from N Roosevelt & 3rd Street and arriving at Fort Pierce via Big Pine Key and Miami Airport. The journey, including transfers, takes approximately 8h 48m.

How far is it from Key West to Port Saint Lucie?

The distance between Key West and Port Saint Lucie is 393 miles. The road distance is 273.9 miles.

How do I travel from Key West to Port Saint Lucie without a car?

The best way to get from Key West to Port Saint Lucie without a car is to bus which takes 8h 48m and costs $50 - $85.

How long does it take to get from Key West to Port Saint Lucie?

It takes approximately 4h 37m to get from Key West to Port Saint Lucie, including transfers.

Where do I catch the Key West to Port Saint Lucie bus from?

Key West to Port Saint Lucie bus services, operated by Key West Transit, depart from N Roosevelt & 3rd Street station.

Where does the Key West to Port Saint Lucie bus arrive?

Key West to Port Saint Lucie bus services, operated by Key West Transit, arrive at Big Pine Key - Auto Store / NAPA MM30 station.

Can I drive from Key West to Port Saint Lucie?

Yes, the driving distance between Key West to Port Saint Lucie is 274 miles. It takes approximately 5h 23m to drive from Key West to Port Saint Lucie.

How do I get a bus ticket from Key West to Port Saint Lucie?

Book your Key West to Port Saint Lucie bus tickets online with Omio.

Where can I stay near Port Saint Lucie?

There are 412+ hotels available in Port Saint Lucie.

Key West to Port Saint Lucie - 7 ways to travel via train, plane, bus, and car

How to get fromKey West to Port Saint Lucie

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There are 7 ways to get from Key West to Port Saint Lucie by plane, bus, bus (Greyhound), car, shuttle, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly to Orlando, bus
best
1. Fly from Key West International Airport (EYW) to Orlando (MCO)plane EYW - MCO
2. Take the bus from Orlando RedCoach Station to Fort Piercebus
4h 37m
$107–721
Drive 272.3 mi
cheapest
1. Drive from Key West to Port Saint Luciecar 272.3 mi
5h 23m
$50–72
Bus
1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus Lks
2. Take the bus from Big Pine Key to Miami Airport Stationbus
3. Take the bus from Miami Airport to Fort Piercebus
8h 48m
$52–84
Shuttle, bus
1. Take a shuttle bus from Key West, FL to Fort Lauderdale, FL - International Airportshuttle To the Airports
2. Take the bus from Fort Lauderdale Airport to Fort Piercebus Miami–Tallahassee via Orlando
8h 23m
$216–269
Fly to Miami International Airport, train, bus
1. Fly from Key West International Airport (EYW) to Miami International Airport (MIA)plane EYW - MIA
2. Take the train from Miami Airport Station to Fort Lauderdale Stationtrain
3. Take the bus from Fort Lauderdale - Broward Blvd Park and Ride to Fort Piercebus
5h 5m
$75–290
Fly to Orlando Sanford, drive
1. Fly from Key West International Airport (EYW) to Orlando Sanford (SFB)plane EYW - SFB
2. Drive from Orlando-Sanford-Airport-SFB to Port Saint Luciecar
3h 49m
$76–319
Bus, train
1. Take the bus from N Roosevelt & 4th Street to Big Pine Key - Auto Store / NAPA MM30bus Lks
2. Take the bus from Big Pine Key to Miami Airport Stationbus
3. Take the train from Miami Airport Station to Fort Lauderdale Stationtrain
4. Take the bus from Fort Lauderdale - Broward Blvd Park and Ride to Fort Piercebus
9h 30m
$55–90

Key West to Port Saint Lucie by bus, foot, and tram

31Weekly Services

8h 48mAverage Duration

$52Cheapest Price

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Questions & Answers

Map of how to get from Key West to Port Saint Lucie.

Launch map view

Distance: 390.5 mi
Duration: 4h 37m

What companies run services between Key West, FL, USA and Port Saint Lucie, FL, USA?

You can take a bus from N Roosevelt & 3rd Street to Fort Pierce via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami, Airport Intermodal Station, Miami Airport Station, Miami International Airport, and Miami Airport in around 8h 48m.

Airlines

Train operators

Bus operators

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How to get fromKey West to Port Saint Lucieby plane, bus, bus (Greyhound), car, shuttle, or train

There are 7 ways to get from Key West to Port Saint Lucie by plane, bus, bus (Greyhound), car, shuttle, or train

Fly to Orlando, bus

Drive 272.3 mi

Bus

Shuttle, bus

Fly to Miami International Airport, train, bus

Fly to Orlando Sanford, drive

Bus, train