There are 6 ways to get from Key West to Saint James City by ferry, taxi, bus (Greyhound, Flixbus), car, plane, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Ferry, taxi
best- Take the ferry from Key West, FL to Fort Myers Beach, FLferry Key West
- Take the taxi from Fort Myers Beach, FL to Saint James Citytaxi
4h 58m$230–250Drive 296.9 mi
cheapest- Drive from Key West to Saint James Citycar 296.9 mi
6h 40m$55–79Bus
- Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus Lks
- Take the bus from Big Pine Key to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Fort Myers Bus Stopbus
12h 7m$116–167Fly to Ft. Myers, taxi
- Fly from Key West International Airport (EYW) to Ft. Myers (RSW)plane EYW - RSW
- Take the taxi from Ft-Myers-Airport-RSW to Saint James Citytaxi
5h 58m$252–804Fly to Miami International Airport, bus, taxi
- Fly from Key West International Airport (EYW) to Miami International Airport (MIA)plane EYW - MIA
- Take the bus from Miami Airport to Fort Myers 7-11bus
- Take the taxi from Fort Myers 7-11 to Saint James Citytaxi
5h 37m$172–474Fly to Sarasota–Bradenton International Airport, bus, taxi
- Fly from Key West International Airport (EYW) to Sarasota–Bradenton International Airport (SRQ)plane EYW - SRQ
- Take the bus from Sarasota Cattlemen Transfer Center to Fort Myers Bus Stopbus
- Take the taxi from Fort Myers Bus Stop to Saint James Citytaxi
8h 4m$150–470
Key West International Airport (EYW) to Ft. Myers (RSW) flights
Comparing Your Travel Options
The cheapest way to get from Key West to Saint James City is to drive which costs $50 - $80 and takes 6h 40m.
The fastest way to get from Key West to Saint James City is to ferry and taxi which takes 4h 58m and costs $230 - $250.
No, there is no direct bus from Key West to Saint James City. However, there are services departing from N Roosevelt & 3rd Street and arriving at Cape Coral Transfer Center via Big Pine Key, Miami Airport Station and Rosa Parks Transportation Ctr. The journey, including transfers, takes approximately 12h 7m.
The distance between Key West and Saint James City is 173 miles. The road distance is 298.6 miles.
The best way to get from Key West to Saint James City without a car is to ferry and taxi which takes 4h 58m and costs $230 - $250.
It takes approximately 4h 58m to get from Key West to Saint James City, including transfers.
Key West to Saint James City bus services, operated by Key West Transit, depart from N Roosevelt & 3rd Street station.
Key West to Saint James City bus services, operated by Key West Transit, arrive at Big Pine Key - Auto Store / NAPA MM30 station.
Yes, the driving distance between Key West to Saint James City is 299 miles. It takes approximately 6h 40m to drive from Key West to Saint James City.
There are 3767+ hotels available in Saint James City.
What companies run services between Key West, FL, USA and Saint James City, FL, USA?
You can take a bus from N Roosevelt & 3rd Street to Saint James City via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, Rosa Parks Transportation Ctr, and Cape Coral Transfer Center in around 12h 7m.
- Website
- aa.com
Flights from Key West International Airport to Ft. Myers via Charlotte
- Ave. Duration
- 5h 26m
- When
- Every day
- Estimated price
- $140–700
Flights from Key West International Airport to Miami International Airport
- Ave. Duration
- 52 min
- When
- Every day
- Estimated price
- $35–290
Flights from Key West International Airport to Sarasota–Bradenton International Airport via Miami International Airport
- Ave. Duration
- 3h 56m
- When
- Every day
- Estimated price
- $50–340
Flights from Key West International Airport to Sarasota–Bradenton International Airport via Charlotte
- Ave. Duration
- 5h 22m
- When
- Tuesday
- Estimated price
- $110–550
- Website
- delta.com
Flights from Key West International Airport to Ft. Myers via Atlanta
- Ave. Duration
- 5h 32m
- When
- Every day
- Estimated price
- $130–650
Flights from Key West International Airport to Sarasota–Bradenton International Airport via Atlanta
- Ave. Duration
- 5h 32m
- When
- Every day
- Estimated price
- $100–490
- Website
- allegiantair.com
Flights from Key West International Airport to Sarasota–Bradenton International Airport via Covington
- Ave. Duration
- 6h 56m
- When
- Friday
- Estimated price
- $150–650
Flights from Key West International Airport to Sarasota–Bradenton International Airport via Asheville
- Ave. Duration
- 7h 2m
- When
- Sunday
- Estimated price
- $110–550
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30
- Ave. Duration
- 54 min
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- Key West Transit
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Big Pine Key to Miami Airport Station
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $23–35
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Miami Airport Station to Fort Myers Bus Stop
- Ave. Duration
- 3h 25m
- Frequency
- 3 times a day
- Estimated price
- $25–40
- Schedules at
- Flixbus USA
Bus from Sarasota Cattlemen Transfer Center to Fort Myers Bus Stop
- Ave. Duration
- 1h 20m
- Frequency
- 3 times a day
- Estimated price
- $11–17
- Schedules at
- Flixbus USA
- Phone
- +1 877 733 0724
- Website
- RedCoach
Bus from Miami Airport to Fort Myers 7-11
- Ave. Duration
- 2h 50m
- Frequency
- Once daily
- Estimated price
- $40–60
- Website
- RedCoach
- Phone
- +1 239-463-5733
- Website
- Key West Express
Ferry from Key West, FL to Fort Myers Beach, FL
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $130
- Website
- Key West Express
- Ave. Duration
- 54 min
- Estimated price
- $75–140
Island Taxi
- Phone
- +1 239-472-4888
- Website
- islandtaxi.com
CT TAXI Transportation LLC
- Phone
- +1 239-218-9590
Gulf Coast Car Service
- Phone
- +1 941-391-8800
- Website
- gulfcoastcarservice.com
EJ Taxi
CT TAXI Transportation LLC
- Phone
- +1 239-218-9590
Gulf Coast Car Service
- Phone
- +1 941-391-8800
- Website
- gulfcoastcarservice.com
Island Taxi
- Phone
- +1 239-472-4888
- Website
- islandtaxi.com
CT TAXI Transportation LLC
- Phone
- +1 239-218-9590
Gulf Coast Car Service
- Phone
- +1 941-391-8800
- Website
- gulfcoastcarservice.com
EJ Taxi
CT TAXI Transportation LLC
- Phone
- +1 239-218-9590
Gulf Coast Car Service
- Phone
- +1 941-391-8800
- Website
- gulfcoastcarservice.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide











