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How to get fromKey West to San Antonioby plane, bus (Greyhound, Flixbus), car, bus, or ferry

Find Transport to San Antonio

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There are 5 ways to get from Key West to San Antonio by plane, bus (Greyhound, Flixbus), car, bus, or ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to San Antonio International Airport

    best
    1. Fly from Key West International Airport (EYW) to San Antonio International Airport (SAT)plane plane EYW - SAT
    5h 37m
    $154–716

  2. Fly to Austin-Bergstrom International Airport, bus

    cheapest
    1. Fly from Key West International Airport (EYW) to Austin-Bergstrom International Airport (AUS)plane plane EYW - AUS
    2. Take the bus from Austin, TX - UT Austin to San Antonio, TX - E Commerce Stbus bus
    8h 54m
    $152–644

  3. Bus

    1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Tallahasseebus bus
    4. Take the bus from Tallahassee to Houston Bus Stationbus bus
    5. Take the bus from Houston Bus Station to San Antonio Bus Stationbus bus
    41h 22m
    $251–419

  4. Drive  1,519.1 mi

    1. Drive from Key West to San Antoniocar car 1,519.1 mi
    26h 14m
    $278–401

  5. Ferry, bus, drive

    1. Take the ferry from Key West, FL to Fort Myers Beach, FLferry ferry
    2. Take the bus from Fort Myers to Clewistonbus bus
    3. Drive from Clewiston to Port St Luciecar car
    4. Take the bus from Port St Lucie to Atlanta Bus Stationbus bus
    5. Take the bus from Atlanta Bus Station to Houston Bus Stationbus bus
    6. Take the bus from Hyatt Regency Galleria Houston to San Antoniobus bus
    41h 31m
    $561–749

Key West to San Antonio by bus and foot

Calendar7Weekly Services
Duration41h 22mAverage Duration
Ticket$251Cheapest Price
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Comparing Your Travel Options

Map of how to get from Key West to San Antonio.ExpandLaunch map view
  • Distance: 1,094.3 mi
  • Duration: 5h 37m

What companies run services between Key West, FL, USA and San Antonio, TX, USA?

American Airlines, Delta, and three other airlines fly from Key West International Airport (EYW) to San Antonio International Airport (SAT) every 3 hours. Alternatively, you can take a bus from N Roosevelt & 3rd Street to San Antonio Bus Station via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, Tallahassee, and Houston Bus Station in around 41h 22m.

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