There are 3 ways to get from Key West to San Diego by plane, bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Key West International Airport (EYW) to San Diego International Airport (SAN)plane EYW - SAN
7h 38m$192–764Bus, train
- Take the bus from N Roosevelt & 4th Street to Big Pine Key - Auto Store / NAPA MM30bus
- Take the bus from Big Pine Key to Miami Airport Stationbus
- Take the train from Miami Amtrak Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain
- Take the train from Fullerton Amtrak Station to San Diegotrain
4d 4h$1,435–3,052Drive 2,773.5 mi
- Drive from Key West to San Diegocar 2,773.5 mi
45h 53m$507–732
Key West to San Diego by bus, foot, taxi, and train
Questions & Answers
The cheapest way to get from Key West to San Diego is to fly which costs $190 - $800 and takes 7h 38m.
The fastest way to get from Key West to San Diego is to fly which takes 7h 38m and costs $190 - $800.
The distance between Key West and San Diego is 2226 miles. The road distance is 2789.7 miles.
The best way to get from Key West to San Diego without a car is to bus and train which takes 4 days 4h and costs $1,400 - $3,100.
It takes approximately 7h 38m to get from Key West to San Diego, including transfers.
San Diego is 3h behind Key West. It is currently 1:45 AM in Key West and 10:45 PM in San Diego.
Yes, the driving distance between Key West to San Diego is 2790 miles. It takes approximately 45h 53m to drive from Key West to San Diego.
There are 2187+ hotels available in San Diego.
What companies run services between Key West, FL, USA and San Diego, CA, USA?
American Airlines and Delta fly from Key West International Airport (EYW) to San Diego International Airport (SAN) 5 times a day.
- Website
- delta.com
Flights from Key West International Airport to San Diego International Airport via Atlanta
- Ave. Duration
- 8h 8m
- When
- Every day
- Estimated price
- $200–800
- Website
- aa.com
Flights from Key West International Airport to San Diego International Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 33m
- When
- Every day
- Estimated price
- $180–750
Flights from Key West International Airport to San Diego International Airport via Charlotte
- Ave. Duration
- 10h 21m
- When
- Sunday
- Estimated price
- $220–850
Flights from Key West International Airport to San Diego International Airport via Miami
- Ave. Duration
- 11h 11m
- When
- Wednesday
- Estimated price
- $190–750
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Miami Amtrak Station to Chicago Union Station
- Ave. Duration
- 46h 40m
- Frequency
- Once daily
- Estimated price
- $650–1,400
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Fullerton Amtrak Station
- Ave. Duration
- 42h 44m
- Frequency
- Once daily
- Estimated price
- $700–1,500
- Website
- https://www.amtrak.com/home.html
Train from Fullerton Amtrak Station to San Diego
- Ave. Duration
- 2h 26m
- Frequency
- Hourly
- Estimated price
- $30–70
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from N Roosevelt & 4th Street to Big Pine Key - Auto Store / NAPA MM30
- Ave. Duration
- 53 min
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Big Pine Key to Miami Airport Station
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $20–40
- Website
- https://www.greyhound.com/
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Big Pine Key to Miami Airport Station
- Ave. Duration
- 3h 35m
- Frequency
- Twice daily
- Estimated price
- $35–55
- Book at
- https://www.jeffersonlines.com
- Adult
- $35–55
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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