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How to get fromKey West to San Diegoby plane, bus, train, or car

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There are 3 ways to get from Key West to San Diego by plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Key West International Airport (EYW) to San Diego International Airport (SAN)plane plane EYW - SAN
    7h 39m
    $152–664
  2. Bus, train

    1. Take the bus from N Roosevelt & 4th Street to Big Pine Key - Auto Store / NAPA MM30bus bus
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the train from Miami Amtrak Station to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain train
    5. Take the train from Fullerton Amtrak Station to San Diegotrain train
    4d 4h
    $2,398–3,852
  3. Drive  2,783.2 mi

    1. Drive from Key West to San Diegocar car 2,783.2 mi
    45h 29m
    $476–688

Key West to San Diego by bus, foot, taxi, and train

Calendar7Weekly Services
Duration4d 4hAverage Duration
Ticket$2,398Cheapest Price
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Comparing Your Travel Options

What companies run services between Key West, FL, USA and San Diego, CA, USA?

United Airlines, American Airlines, and three other airlines fly from Key West International Airport (EYW) to San Diego International Airport (SAN) 5 times a day.

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Train operators
Bus operators

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