Rome2Rio

How to get fromKey West to San Franciscoby plane, bus, train, car, or shuttle

Find Transport to San Francisco

See all options

There are 6 ways to get from Key West to San Francisco by plane, bus, train, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to San Francisco International Airport

    best
    1. Fly from Key West International Airport (EYW) to San Francisco International Airport (SFO)plane plane EYW - SFO
    9h 1m
    $151–526

  2. Fly to Sonoma County Airport, shuttle

    cheapest
    1. Fly from Key West International Airport (EYW) to Sonoma County Airport (STS)plane plane EYW - STS
    2. Take a shuttle bus from Santa Rosa Airport to San Francisco Pier 27shuttle bus
    21h 42m
    $147–514

  3. Bus, train

    1. Take the bus from N Roosevelt & 4th Street to Big Pine Key - Auto Store / NAPA MM30bus bus
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the train from Miami Amtrak Station to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to Richmondtrain train
    4d 12h
    $1,444–3,074

  4. Drive 3,165.5 mi

    1. Drive from Key West to San Franciscocar car 3,165.5 mi
    2d 5h
    $578–835

  5. Fly to Norman Y. Mineta San José International Airport, Caltrain

    1. Fly from Key West International Airport (EYW) to Norman Y. Mineta San José International Airport (SJC)plane plane EYW - SJC
    2. Take the train from Santa Clara Caltrain Northbound to San Francisco Caltrain Northboundtrain train
    9h 55m
    $214–779

  6. Fly to Sacramento International Airport, train

    1. Fly from Key West International Airport (EYW) to Sacramento International Airport (SMF)plane plane EYW - SMF
    2. Take the train from Sacramento to Richmondtrain train
    12h 11m
    $253–875

Key West to San Francisco by bus, foot, taxi, train, and subway

Calendar7Weekly Services
Duration4d 12hAverage Duration
Ticket$1,444Cheapest Price
See schedules

Questions & Answers

Map of how to get from Key West to San Francisco.ExpandLaunch map view
  • Distance: 2,560.8 mi
  • Duration: 9h 1m

What companies run services between Key West, FL, USA and San Francisco, CA, USA?

Delta and American Airlines fly from Key West International Airport (EYW) to San Francisco International Airport (SFO) every 4 hours.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound