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How to get fromKey West to San Franciscoby plane, bus, train, car, or shuttle

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There are 6 ways to get from Key West to San Francisco by plane, bus, train, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to San Francisco International Airport

    best
    1. Fly from Key West International Airport (EYW) to San Francisco International Airport (SFO)plane plane EYW - SFO
    9h 7m
    $141–576

  2. Bus, train

    1. Take the bus from N Roosevelt & 4th Street to Big Pine Key - Auto Store / NAPA MM30bus bus
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the train from Miami Amtrak Station to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to Richmondtrain train
    4d 12h
    $2,447–3,969

  3. Drive  3,165.5 mi

    1. Drive from Key West to San Franciscocar car 3,165.5 mi
    2d 5h
    $541–782

  4. Fly to Norman Y. Mineta San José International Airport, Caltrain

    1. Fly from Key West International Airport (EYW) to Norman Y. Mineta San José International Airport (SJC)plane plane EYW - SJC
    2. Take the train from Santa Clara Caltrain Northbound to San Francisco Caltrain Northboundtrain train
    11h 46m
    $204–779

  5. Fly to Sonoma County Airport, shuttle

    1. Fly from Key West International Airport (EYW) to Sonoma County Airport (STS)plane plane EYW - STS
    2. Take a shuttle bus from Santa Rosa Airport to San Francisco Pier 27shuttle bus
    22h
    $167–624

  6. Fly to Sacramento International Airport, train

    1. Fly from Key West International Airport (EYW) to Sacramento International Airport (SMF)plane plane EYW - SMF
    2. Take the train from Sacramento to Richmondtrain train
    12h 37m
    $238–890

Key West to San Francisco by bus, foot, taxi, train, and subway

Calendar7Weekly Services
Duration4d 12hAverage Duration
Ticket$2,447Cheapest Price
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Comparing Your Travel Options

Map of how to get from Key West to San Francisco.ExpandLaunch map view
  • Distance: 2,560.8 mi
  • Duration: 9h 7m

What companies run services between Key West, FL, USA and San Francisco, CA, USA?

Delta, American Airlines, and United Airlines fly from Key West International Airport (EYW) to San Francisco International Airport (SFO) every 4 hours.

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Want to know more about travelling around United States

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