There are 5 ways to get from Key West to Sanibel Island by ferry, bus (Greyhound, Flixbus), car, plane, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Ferry
best- Take the ferry from Key West, FL to Fort Myers Beach, FLferry Key West
4h 17m$160–175Drive 278.7 mi
cheapest- Drive from Key West to Sanibel Islandcar 278.7 mi
6h 10m$51–74Bus
- Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus Lks
- Take the bus from Big Pine Key to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Fort Myers Bus Stopbus
11h 51m$93–147Fly to Ft. Myers
- Fly from Key West International Airport (EYW) to Ft. Myers (RSW)plane EYW - RSW
5h 36m$557–904Fly to Miami International Airport, bus
- Fly from Key West International Airport (EYW) to Miami International Airport (MIA)plane EYW - MIA
- Take the bus from Miami Airport to Fort Myersbus
5h 29m$152–414
Key West International Airport (EYW) to Ft. Myers (RSW) flights
Questions & Answers
The cheapest way to get from Key West to Sanibel Island is to drive which costs $50 - $75 and takes 6h 10m.
The fastest way to get from Key West to Sanibel Island is to ferry which takes 4h 17m and costs $160 - $180.
No, there is no direct bus from Key West to Sanibel Island. However, there are services departing from N Roosevelt & 3rd Street and arriving at Cape Coral Transfer Center via Big Pine Key, Miami Airport Station and Rosa Parks Transportation Ctr. The journey, including transfers, takes approximately 11h 51m.
No, there is no direct ferry from Key West to Sanibel Island. However, there are services departing from Key West, FL and arriving at Fort Myers Beach, FL via . The journey, including transfers, takes approximately 4h 17m.
The distance between Key West and Sanibel Island is 148 miles. The road distance is 280.3 miles.
The best way to get from Key West to Sanibel Island without a car is to ferry which takes 4h 17m and costs $160 - $180.
It takes approximately 4h 17m to get from Key West to Sanibel Island, including transfers.
Key West to Sanibel Island bus services, operated by Key West Transit, depart from N Roosevelt & 3rd Street station.
The best way to get from Key West to Sanibel Island is to bus which takes 11h 51m and costs $90 - $150. Alternatively, you can fly, which costs $550 - $950 and takes 5h 36m.
Key West to Sanibel Island bus services, operated by Key West Transit, arrive at Big Pine Key - Auto Store / NAPA MM30 station.
What companies run services between Key West, FL, USA and Sanibel Island, FL, USA?
Key West Express operates a ferry from Key West, FL to Fort Myers Beach, FL once daily. Tickets cost $130 and the journey takes 4h. Alternatively, you can take a bus from N Roosevelt & 3rd Street to Sanibel Island via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, Rosa Parks Transportation Ctr, and Cape Coral Transfer Center in around 11h 51m.
- Website
- aa.com
Flights from Key West International Airport to Ft. Myers via Charlotte
- Ave. Duration
- 7h 58m
- When
- Every day
- Estimated price
- $110–500
Flights from Key West International Airport to Miami International Airport
- Ave. Duration
- 58 min
- When
- Every day
- Estimated price
- $30–230
- Website
- delta.com
Flights from Key West International Airport to Ft. Myers via Atlanta
- Ave. Duration
- 5h 46m
- When
- Every day
- Estimated price
- $100–470
- Website
- flybreeze.com
Flights from Key West International Airport to Ft. Myers via Raleigh/Durham
- Ave. Duration
- 6h 12m
- When
- Monday and Friday
- Estimated price
- $470–800
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30
- Ave. Duration
- 54 min
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Big Pine Key to Miami Airport Station
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $20–40
- Website
- https://www.greyhound.com/
- Website
- greyhound.com
Bus from Big Pine Key to Miami Airport Station
- Ave. Duration
- 3h 35m
- Frequency
- Twice daily
- Schedules at
- greyhound.com
- Website
- flixbus.com
Bus from Miami Airport Station to Fort Myers Bus Stop
- Ave. Duration
- 3h 25m
- Frequency
- 3 times a day
- Schedules at
- flixbus.com
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Miami Airport Station to Fort Myers Bus Stop
- Ave. Duration
- 3h 25m
- Frequency
- 3 times a day
- Estimated price
- $25–45
- Schedules at
- flixbus.com
- Phone
- +1 877 733 0724
- Website
- redcoachusa.com
Bus from Miami Airport to Fort Myers
- Ave. Duration
- 2h 55m
- Frequency
- 4 times a day
- Estimated price
- $40–80
- Website
- https://www.redcoachusa.com
- Phone
- +1 239-463-5733
- Website
- keywestexpress.net
Ferry from Key West, FL to Fort Myers Beach, FL
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $130
- Website
- https://www.keywestexpress.net
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More Questions & Answers
Yes, the driving distance between Key West to Sanibel Island is 280 miles. It takes approximately 6h 10m to drive from Key West to Sanibel Island.
There are 3626+ hotels available in Sanibel Island.