There are 3 ways to get from Key West to Santo Domingo by plane, bus, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Las Américas International Airport
best- Fly from Key West International Airport (EYW) to Las Américas International Airport (SDQ)plane EYW - SDQ
5h 11m$132–504Fly to Cibao International Airport, bus
- Fly from Key West International Airport (EYW) to Cibao International Airport (STI)plane EYW - STI
- Take the bus from La Vega to Santo Domingobus
6h 22m$295–1,370Fly to Punta Cana International Airport, shuttle
- Fly from Key West International Airport (EYW) to Punta Cana International Airport (PUJ)plane EYW - PUJ
- Take a shuttle bus from Punta Cana Airport to Santo Domingo
6h 47m$242–589
Key West International Airport (EYW) to Las Américas International Airport (SDQ) flights
Comparing Your Travel Options
The cheapest way to get from Key West to Santo Domingo is to fly which costs $130 - $550 and takes 5h 11m.
The fastest way to get from Key West to Santo Domingo is to fly which takes 5h 11m and costs $130 - $550.
The distance between Key West and Santo Domingo is 1453 km.
It takes approximately 5h 11m to get from Key West to Santo Domingo, including transfers.
There are 969+ hotels available in Santo Domingo.
What companies run services between Key West, FL, USA and Santo Domingo, Dominican Republic?
American Airlines, Breeze Airways, and JetBlue Airways fly from Key West International Airport (EYW) to Las Américas International Airport (SDQ) 3 times a day.
- Website
- aa.com
Flights from Key West International Airport to Las Américas International Airport via Miami
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- $90–460
Flights from Key West International Airport to Cibao International Airport via Miami
- Ave. Duration
- 3h 48m
- When
- Every day
- Estimated price
- $240–1,300
Flights from Key West International Airport to Punta Cana International Airport via Miami
- Ave. Duration
- 4h 27m
- When
- Every day
- Estimated price
- $85–430
- Website
- jetblue.com
Flights from Key West International Airport to Las Américas International Airport via Orlando
- Ave. Duration
- 5h 4m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $110–550
- Website
- united.com
Flights from Key West International Airport to Cibao International Airport via Newark
- Ave. Duration
- 8h 1m
- When
- Every day
- Estimated price
- $550–2,200
- Website
- delta.com
Flights from Key West International Airport to Punta Cana International Airport via Atlanta
- Ave. Duration
- 7h
- When
- Every day
- Estimated price
- $140–600
- Website
- arajet.com
Flights from Key West International Airport to Punta Cana International Airport via Orlando Sanford
- Ave. Duration
- 7h 11m
- When
- Friday
- Estimated price
- $180–900
- Phone
- (809) 221 - 4422
- [email protected]
- Website
- caribetours.com.do
Bus from La Vega to Santo Domingo
- Ave. Duration
- 2h
- Frequency
- Every 20 minutes
- Estimated price
- $3–6
- Schedules at
- caribetours.com.do
- Book at
- caribetours.com.do
- Phone
- (407) 420-7646
- [email protected]
- Website
- Dominican Airport Transfers
Shuttle from Punta Cana Airport to Santo Domingo
- Ave. Duration
- 2h
- Frequency
- On demand
- Estimated price
- $145
- Website
- Dominican Airport Transfers
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