How to get fromKey West to Santo Domingoby plane, bus, or shuttle

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There are 3 ways to get from Key West to Santo Domingo by plane, bus, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly to Las Américas International Airport
best
1. Fly from Key West International Airport (EYW) to Las Américas International Airport (SDQ)plane EYW - SDQ
6h
$132–474
Fly to Cibao International Airport, bus
1. Fly from Key West International Airport (EYW) to Cibao International Airport (STI)plane EYW - STI
2. Take the bus from La Vega to Santo Domingobus
6h 54m
$275–1,170
Fly to Punta Cana International Airport, shuttle
1. Fly from Key West International Airport (EYW) to Punta Cana International Airport (PUJ)plane EYW - PUJ
2. Take a shuttle bus from Punta Cana Airport to Santo Domingoshuttle
7h 24m
$242–549

Key West International Airport (EYW) to Las Américas International Airport (SDQ) flights

21Weekly Planes

6h 6mAverage Duration

$91Cheapest Price

Questions & Answers

Map of how to get from Key West to Santo Domingo.

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Distance: 1,453.2 km
Duration: 6h

What companies run services between Key West, FL, USA and Santo Domingo, Dominican Republic?

American Airlines and United Airlines fly from Key West International Airport (EYW) to Las Américas International Airport (SDQ) 3 times a day.

Airlines

Bus operators

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Santo Domingo(opens in a new window), Dominican Republic(opens in a new window)

Santo Domingo, once known as Santo Domingo de Guzmán, known as Ciudad Trujillo between 1936 and 1961, is the capital and largest city of the Dominican Republic and the largest metropolitan area in the Caribbean by population. the city and immediate surrounding area (the Distrito Nacional) had a population of 1,029,110 while the total population is 3,798,699 when including Greater Santo Domingo (the "metropolitan area"). The city is coterminous with the boundaries of the Distrito Nacional ("D.N.", "National District"), itself bordered on three sides by Santo Domingo Province.

Places to stay in Santo Domingo

Barceló Santo Domingo(Opens in a new window)

8.2Very Good

Hodelpa Nicolás de Ovando(Opens in a new window)

8.5Very Good

Hodelpa Caribe Colonial(Opens in a new window)

8.1Very Good

Billini Hotel, Historic Luxury(Opens in a new window)

8.4Very Good

Rome2Rio makes travelling from Key West to Santo Domingo easy.

Rome2Rio is a door-to-door travel information and booking engine, helping you get to and from any location in the world. Find all the transport options for your trip from Key West to Santo Domingo right here. Rome2Rio displays up to date schedules, route maps, journey times and estimated fares from relevant transport operators, ensuring you can make an informed decision about which option will suit you best. Rome2Rio also offers online bookings for selected operators, making reservations easy and straightforward.