There are 4 ways to get from Key West to Santo Domingo by plane, bus, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Las Américas International Airport
best- Fly from Key West International Airport (EYW) to Las Américas International Airport (SDQ)plane EYW - SDQ
5h 45m$127–484Fly to Cibao International Airport, bus
- Fly from Key West International Airport (EYW) to Cibao International Airport (STI)plane EYW - STI
- Take the bus from La Vega to Santo Domingobus
7h 5m$275–1,270Fly to Punta Cana International Airport, shuttle
- Fly from Key West International Airport (EYW) to Punta Cana International Airport (PUJ)plane EYW - PUJ
- Take a shuttle bus from Punta Cana Airport to Santo Domingo
6h 53m$242–579Fly to La Romana International Airport, shuttle
- Fly from Key West International Airport (EYW) to La Romana International Airport (LRM)plane EYW - LRM
- Take a shuttle bus from Altos de Chavón to Santo Domingo Airport
12h 4m$296–861
Key West International Airport (EYW) to Las Américas International Airport (SDQ) flights
Comparing Your Travel Options
The cheapest way to get from Key West to Santo Domingo is to fly which costs $120 - $490 and takes 5h 45m.
The fastest way to get from Key West to Santo Domingo is to fly which takes 5h 45m and costs $120 - $490.
The distance between Key West and Santo Domingo is 1453 km.
It takes approximately 5h 45m to get from Key West to Santo Domingo, including transfers.
Santo Domingo is 1h ahead of Key West. It is currently 7:13 AM in Key West and 8:13 AM in Santo Domingo.
There are 1011+ hotels available in Santo Domingo.
What companies run services between Key West, FL, USA and Santo Domingo, Dominican Republic?
American Airlines, Breeze Airways, and JetBlue Airways fly from Key West International Airport (EYW) to Las Américas International Airport (SDQ) twice daily.
- Website
- aa.com
Flights from Key West International Airport to Las Américas International Airport via Miami
- Ave. Duration
- 5h 18m
- When
- Monday, Thursday, Saturday, Friday, and Sunday
- Estimated price
- $85–440
Flights from Key West International Airport to Cibao International Airport via Miami
- Ave. Duration
- 4h 31m
- When
- Monday, Thursday, and Saturday
- Estimated price
- $220–1,200
Flights from Key West International Airport to Punta Cana International Airport via Miami
- Ave. Duration
- 4h 33m
- When
- Monday, Thursday, and Saturday
- Estimated price
- $85–420
Flights from Key West International Airport to La Romana International Airport via Miami
- Ave. Duration
- 18h 25m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–700
- Website
- neosair.it
Flights from Key West International Airport to La Romana International Airport via Miami, Havana
- Ave. Duration
- 9h 22m
- When
- Saturday
- Estimated price
- $250–2,000
- Website
- jetblue.com
Flights from Key West International Airport to Las Américas International Airport via Orlando
- Ave. Duration
- 4h 54m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $100–490
- Website
- united.com
Flights from Key West International Airport to Cibao International Airport via Newark
- Ave. Duration
- 8h 1m
- When
- Every day
- Estimated price
- $500–2,000
- Website
- delta.com
Flights from Key West International Airport to Punta Cana International Airport via Atlanta
- Ave. Duration
- 7h
- When
- Every day
- Estimated price
- $140–600
- Website
- arajet.com
Flights from Key West International Airport to Punta Cana International Airport via Orlando Sanford
- Ave. Duration
- 7h 15m
- When
- Friday
- Estimated price
- $170–900
- Phone
- (809) 221 - 4422
- [email protected]
- Website
- caribetours.com.do
Bus from La Vega to Santo Domingo
- Ave. Duration
- 2h
- Frequency
- Every 20 minutes
- Estimated price
- $3–6
- Schedules at
- caribetours.com.do
- Book at
- caribetours.com.do
- Phone
- (407) 420-7646
- [email protected]
- Website
- Dominican Airport Transfers
Shuttle from Punta Cana Airport to Santo Domingo
- Ave. Duration
- 2h
- Frequency
- On demand
- Estimated price
- $145
- Website
- Dominican Airport Transfers
Shuttle from Altos de Chavón to Santo Domingo Airport
- Ave. Duration
- 1h 15m
- Frequency
- On demand
- Estimated price
- $99
- Website
- Dominican Airport Transfers
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