There are 3 ways to get from Key West to Santo Domingo by plane, bus, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Las Américas International Airport
best- Fly from Key West International Airport (EYW) to Las Américas International Airport (SDQ)plane EYW - SDQ
6h 1m$137–524Fly to Cibao International Airport, bus
- Fly from Key West International Airport (EYW) to Cibao International Airport (STI)plane EYW - STI
- Take the bus from La Vega to Santo Domingobus
6h 22m$300–1,370Fly to Punta Cana International Airport, shuttle
- Fly from Key West International Airport (EYW) to Punta Cana International Airport (PUJ)plane EYW - PUJ
- Take a shuttle bus from Punta Cana Airport to Santo Domingo
7h$242–599
Key West International Airport (EYW) to Las Américas International Airport (SDQ) flights
Comparing Your Travel Options
The cheapest way to get from Key West to Santo Domingo is to fly which costs $130 - $550 and takes 6h 1m.
The fastest way to get from Key West to Santo Domingo is to fly which takes 6h 1m and costs $130 - $550.
The distance between Key West and Santo Domingo is 1453 km.
It takes approximately 6h 1m to get from Key West to Santo Domingo, including transfers.
There are 1006+ hotels available in Santo Domingo.
What companies run services between Key West, FL, USA and Santo Domingo, Dominican Republic?
American Airlines, United Airlines, and two other airlines fly from Key West International Airport (EYW) to Las Américas International Airport (SDQ) 4 times a day.
- Website
- aa.com
Flights from Key West International Airport to Las Américas International Airport via Miami
- Ave. Duration
- 7h 24m
- When
- Every day
- Estimated price
- $95–480
Flights from Key West International Airport to Cibao International Airport via Miami
- Ave. Duration
- 3h 48m
- When
- Every day
- Estimated price
- $250–1,300
Flights from Key West International Airport to Punta Cana International Airport via Miami
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- $85–440
- Website
- united.com
Flights from Key West International Airport to Las Américas International Airport via Newark
- Ave. Duration
- 8h 31m
- When
- Every day
- Estimated price
- $210–850
- Website
- jetblue.com
Flights from Key West International Airport to Las Américas International Airport via Orlando
- Ave. Duration
- 5h 11m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $110–550
- Website
- delta.com
Flights from Key West International Airport to Punta Cana International Airport via Atlanta
- Ave. Duration
- 7h
- When
- Every day
- Estimated price
- $140–650
- Phone
- (809) 221 - 4422
- [email protected]
- Website
- caribetours.com.do
Bus from La Vega to Santo Domingo
- Ave. Duration
- 2h
- Frequency
- Every 20 minutes
- Estimated price
- $3–6
- Schedules at
- caribetours.com.do
- Book at
- caribetours.com.do
- Phone
- (407) 420-7646
- [email protected]
- Website
- Dominican Airport Transfers
Shuttle from Punta Cana Airport to Santo Domingo
- Ave. Duration
- 2h
- Frequency
- On demand
- Estimated price
- $145
- Website
- Dominican Airport Transfers
Want to know more about travelling around the world?
Rome2Rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including Heading to Europe? Read this before you buy a Eurail Pass, Need to know: Eurostar, and How to get from Southend Airport into central London - to help you get the most out of your next trip.