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How to get fromKey West to South Padre Islandby plane, taxi, ferry, bus, car, bus (Greyhound), or bus (Greyhound, Flixbus)

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There are 8 ways to get from Key West to South Padre Island by plane, taxi, ferry, bus, car, bus (Greyhound), or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Rio Grande Valley International Airport, taxi

    best
    1. Fly from Key West International Airport (EYW) to Rio Grande Valley International Airport (HRL)plane plane EYW - HRL
    2. Take the taxi from Rio Grande Valley International Airport (HRL) to South Padre Islandtaxi taxi
    7h 58m
    $212–634

  2. Fly to Brownsville-South Padre Island International Airport

    cheapest
    1. Fly from Key West International Airport (EYW) to Brownsville-South Padre Island International Airport (BRO)plane plane EYW - BRO
    7h 55m
    $129–525

  3. Ferry, bus, taxi

    1. Take the ferry from Key West, FL to Marco Island, FLferry ferry
    2. Take the bus from Naples, FL to Tallahassee, FLbus bus
    3. Take the bus from Tallahassee to Houston Bus Stationbus bus
    4. Take the bus from Houston - Telephone Rd to Brownsville Bus Stationbus bus
    5. Take the taxi from Brownsville Bus Station to South Padre Islandtaxi taxi
    39h 25m
    $561–770

  4. Drive  1,692.7 mi

    1. Drive from Key West to South Padre Islandcar car 1,692.7 mi
    30h 23m
    $300–432

  5. Fly to Mcallen Miller International Airport, bus

    1. Fly from Key West International Airport (EYW) to Mcallen Miller International Airport (MFE)plane plane EYW - MFE
    2. Take the bus from McAllen Central Station to La Plaza at Brownsvillebus bus
    10h 36m
    $143–549

  6. Ferry, bus

    1. Take the ferry from Key West, FL to Fort Myers Beach, FLferry ferry
    2. Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus bus
    3. Take the bus from Tampa Bus Station to Tallahasseebus bus
    4. Take the bus from Tallahassee to Houston Bus Stationbus bus
    5. Take the bus from Houston - Harrisburg Blvd to Brownsville Bus Stationbus bus
    41h
    $452–601

  7. Bus via Houston

    1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Tallahasseebus bus
    4. Take the bus from Tallahassee to Houston Bus Stationbus bus
    5. Take the bus from Houston - Harrisburg Blvd to Brownsville Bus Stationbus bus
    46h 58m
    $347–515

  8. Bus

    1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Tallahasseebus bus
    4. Take the bus from Tallahassee to Houston Bus Stationbus bus
    5. Take the bus from Houston Bus Station to La Plaza at Brownsvillebus bus
    47h 48m
    $337–540

Key West International Airport (EYW) to Rio Grande Valley International Airport (HRL) flights

Calendar8Weekly Planes
Duration8h 14mAverage Duration
Ticket$103Cheapest Price
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Comparing Your Travel Options

Map of how to get from Key West to South Padre Island.ExpandLaunch map view
  • Distance: 1,040.6 mi
  • Duration: 7h 58m

What companies run services between Key West, FL, USA and South Padre Island, TX, USA?

American Airlines and United Airlines fly from Key West International Airport (EYW) to Brownsville-South Padre Island International Airport (BRO) twice daily. Alternatively, you can take a bus from N Roosevelt & 3rd Street to South Padre Island via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, Tallahassee, Houston Bus Station, Houston - Harrisburg Blvd, La Plaza at Brownsville, and Las Palmas Port Isabel in around 46h 58m.

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